Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery

Handle URI:
http://hdl.handle.net/10754/625494
Title:
Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery
Authors:
Rhamani, Saher; Chaix, Arnaud; Aggad, Dina; Hoang, Phuong Mai; Moosa, Basem ( 0000-0002-2350-4100 ) ; Garcia, Marcel; Gary-Bobo, Magali; Charnay, Clarence; Almalik, Abdulaziz; Durand, Jean-Olivier; Khashab, Niveen M. ( 0000-0003-2728-0666 )
Abstract:
The synthesis of gold core degradable mesoporous organosilica shell nanoparticles is described. The nanopaticles were very efficient for two-photon luminescence imaging of cancer cells and for in vitro gemcitabine monophosphate delivery, allowing promising theranostic applications in the nanomedicine field.
KAUST Department:
Advanced Membranes and Porous Materials Research Center
Citation:
Rhamani S, Chaix A, Aggad D, Hoang P, Moosa B, et al. (2017) Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery. Mol Syst Des Eng. Available: http://dx.doi.org/10.1039/c7me00058h.
Publisher:
Royal Society of Chemistry (RSC)
Journal:
Mol. Syst. Des. Eng.
Issue Date:
12-Sep-2017
DOI:
10.1039/c7me00058h
Type:
Article
ISSN:
2058-9689
Sponsors:
We thank King Abdullah University for science and Technology (KAUST) and King Abdulaziz City of Science and Technology (KACST) for the financial support. The Erasmus Mundus grant for S.R. is gratefully acknowledged. The rio imaging platform is acknowledged for technical assistance. The authors thank Dr. G. Mouchaham for Adsorption/Desorption of Nitrogen.
Additional Links:
http://pubs.rsc.org/en/Content/ArticleLanding/2017/ME/C7ME00058H#!divAbstract
Appears in Collections:
Articles; Advanced Membranes and Porous Materials Research Center

Full metadata record

DC FieldValue Language
dc.contributor.authorRhamani, Saheren
dc.contributor.authorChaix, Arnauden
dc.contributor.authorAggad, Dinaen
dc.contributor.authorHoang, Phuong Maien
dc.contributor.authorMoosa, Basemen
dc.contributor.authorGarcia, Marcelen
dc.contributor.authorGary-Bobo, Magalien
dc.contributor.authorCharnay, Clarenceen
dc.contributor.authorAlmalik, Abdulazizen
dc.contributor.authorDurand, Jean-Olivieren
dc.contributor.authorKhashab, Niveen M.en
dc.date.accessioned2017-09-21T09:25:33Z-
dc.date.available2017-09-21T09:25:33Z-
dc.date.issued2017-09-12en
dc.identifier.citationRhamani S, Chaix A, Aggad D, Hoang P, Moosa B, et al. (2017) Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery. Mol Syst Des Eng. Available: http://dx.doi.org/10.1039/c7me00058h.en
dc.identifier.issn2058-9689en
dc.identifier.doi10.1039/c7me00058hen
dc.identifier.urihttp://hdl.handle.net/10754/625494-
dc.description.abstractThe synthesis of gold core degradable mesoporous organosilica shell nanoparticles is described. The nanopaticles were very efficient for two-photon luminescence imaging of cancer cells and for in vitro gemcitabine monophosphate delivery, allowing promising theranostic applications in the nanomedicine field.en
dc.description.sponsorshipWe thank King Abdullah University for science and Technology (KAUST) and King Abdulaziz City of Science and Technology (KACST) for the financial support. The Erasmus Mundus grant for S.R. is gratefully acknowledged. The rio imaging platform is acknowledged for technical assistance. The authors thank Dr. G. Mouchaham for Adsorption/Desorption of Nitrogen.en
dc.publisherRoyal Society of Chemistry (RSC)en
dc.relation.urlhttp://pubs.rsc.org/en/Content/ArticleLanding/2017/ME/C7ME00058H#!divAbstracten
dc.rightsArchived with thanks to Mol. Syst. Des. Eng.en
dc.titleGold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Deliveryen
dc.typeArticleen
dc.contributor.departmentAdvanced Membranes and Porous Materials Research Centeren
dc.identifier.journalMol. Syst. Des. Eng.en
dc.eprint.versionPost-printen
dc.contributor.institutionInstitut Charles Gerhardt Montpellier, UMR-5253 CNRS-UM-ENSCM, cc 1701, Place Eugene Bataillon, 34095 Montpellier cedex 05en
dc.contributor.institutionInstitut de Biomolecules Max Mousseron, UMR 5247, Universite de Montpellier, Avenue Charles Flahault, 34095 Montpellier cedex 05 Franceen
dc.contributor.institutionLife sciences and Environment Research Institute, Center of Excellence in Nanomedicine (CENM), King Abdulaziz City for Science and Technology (KACST), Riyadh 11461, Saudi Arabia.en
kaust.authorRhamani, Saheren
kaust.authorChaix, Arnauden
kaust.authorHoang, Phuong Maien
kaust.authorMoosa, Basemen
kaust.authorKhashab, Niveen M.en
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