MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity

Handle URI:
http://hdl.handle.net/10754/625224
Title:
MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity
Authors:
Latrasse, David; Jégu, Teddy; Li, Huchen; Zélicourt, Axel de ( 0000-0003-0797-6308 ) ; Raynaud, Cécile; Legras, Stéphanie; Gust, Andrea; Samajova, Olga; Veluchamy, Alaguraj; Rayapuram, Naganand; Ramirez Prado, Juan Sebastian; Kulikova, Olga; Colcombet, Jean; Bigeard, Jean; Genot, Baptiste; Bisseling, Ton; Benhamed, Moussa ( 0000-0002-4181-1702 ) ; Hirt, Heribert ( 0000-0003-3119-9633 )
Abstract:
Microbial-associated molecular patterns activate several MAP kinases, which are major regulators of the innate immune response in Arabidopsis thaliana that induce large-scale changes in gene expression. Here, we determine whether microbial-associated molecular pattern-triggered gene expression involves modifications at the chromatin level.Histone acetylation and deacetylation are major regulators of microbial-associated molecular pattern-triggered gene expression and implicate the histone deacetylase HD2B in the reprogramming of defence gene expression and innate immunity. The MAP kinase MPK3 directly interacts with and phosphorylates HD2B, thereby regulating the intra-nuclear compartmentalization and function of the histone deacetylase.By studying a number of gene loci that undergo microbial-associated molecular pattern-dependent activation or repression, our data reveal a mechanistic model for how protein kinase signaling directly impacts chromatin reprogramming in plant defense.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division
Citation:
Latrasse D, Jégu T, Li H, de Zelicourt A, Raynaud C, et al. (2017) MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity. Genome Biology 18. Available: http://dx.doi.org/10.1186/s13059-017-1261-8.
Publisher:
Springer Nature
Journal:
Genome Biology
KAUST Grant Number:
CRG4
Issue Date:
6-Jul-2017
DOI:
10.1186/s13059-017-1261-8
Type:
Article
ISSN:
1474-760X
Sponsors:
Funding for the project was provided to HH and MB by a grant of the French National Agency of Research (LabEx Saclay Plant Sciences-SPS ANR-10-LABX-0040-SPS) as well as by grant CRG4 of the King Abdullah University of Science and Technology. Moreover, OS was supported by the Czech Science Foundation GA ČR grant no. GA16-22044S. No ethics approval was required for this project.
Additional Links:
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1261-8
Appears in Collections:
Articles; Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorLatrasse, Daviden
dc.contributor.authorJégu, Teddyen
dc.contributor.authorLi, Huchenen
dc.contributor.authorZélicourt, Axel deen
dc.contributor.authorRaynaud, Cécileen
dc.contributor.authorLegras, Stéphanieen
dc.contributor.authorGust, Andreaen
dc.contributor.authorSamajova, Olgaen
dc.contributor.authorVeluchamy, Alagurajen
dc.contributor.authorRayapuram, Nagananden
dc.contributor.authorRamirez Prado, Juan Sebastianen
dc.contributor.authorKulikova, Olgaen
dc.contributor.authorColcombet, Jeanen
dc.contributor.authorBigeard, Jeanen
dc.contributor.authorGenot, Baptisteen
dc.contributor.authorBisseling, Tonen
dc.contributor.authorBenhamed, Moussaen
dc.contributor.authorHirt, Heriberten
dc.date.accessioned2017-07-19T10:45:01Z-
dc.date.available2017-07-19T10:45:01Z-
dc.date.issued2017-07-06en
dc.identifier.citationLatrasse D, Jégu T, Li H, de Zelicourt A, Raynaud C, et al. (2017) MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity. Genome Biology 18. Available: http://dx.doi.org/10.1186/s13059-017-1261-8.en
dc.identifier.issn1474-760Xen
dc.identifier.doi10.1186/s13059-017-1261-8en
dc.identifier.urihttp://hdl.handle.net/10754/625224-
dc.description.abstractMicrobial-associated molecular patterns activate several MAP kinases, which are major regulators of the innate immune response in Arabidopsis thaliana that induce large-scale changes in gene expression. Here, we determine whether microbial-associated molecular pattern-triggered gene expression involves modifications at the chromatin level.Histone acetylation and deacetylation are major regulators of microbial-associated molecular pattern-triggered gene expression and implicate the histone deacetylase HD2B in the reprogramming of defence gene expression and innate immunity. The MAP kinase MPK3 directly interacts with and phosphorylates HD2B, thereby regulating the intra-nuclear compartmentalization and function of the histone deacetylase.By studying a number of gene loci that undergo microbial-associated molecular pattern-dependent activation or repression, our data reveal a mechanistic model for how protein kinase signaling directly impacts chromatin reprogramming in plant defense.en
dc.description.sponsorshipFunding for the project was provided to HH and MB by a grant of the French National Agency of Research (LabEx Saclay Plant Sciences-SPS ANR-10-LABX-0040-SPS) as well as by grant CRG4 of the King Abdullah University of Science and Technology. Moreover, OS was supported by the Czech Science Foundation GA ČR grant no. GA16-22044S. No ethics approval was required for this project.en
dc.publisherSpringer Natureen
dc.relation.urlhttps://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1261-8en
dc.rightsThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.titleMAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunityen
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.identifier.journalGenome Biologyen
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionInstitute of Plant Sciences Paris-Saclay (IPS2), CNRS, INRA, University Paris-Sud, University of Evry, University Paris-Diderot, Sorbonne Paris-Cite, University of Paris-Saclay, Batiment 630, 91405, Orsay, France.en
dc.contributor.institutionLaboratory of Molecular Biology, Wageningen University, Droevendaalsesteeg 1, 6708PB, Wageningen, The Netherlands.en
dc.contributor.institutionPlateforme Biopuces et séquençage, IGBMC, 1 rue Laurent Fries Parc d'Innovation, 67400, Illkirch, France.en
dc.contributor.institutionCenter for Plant Molecular Biology, University of Tübingen, Auf der Morgenstelle 32, 72076, Tübingen, Germany.en
dc.contributor.institutionCentre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Palacký University Olomouc, Šlechtitelů 27, 783 71, Olomouc, Czech Republic.en
kaust.authorZélicourt, Axel deen
kaust.authorVeluchamy, Alagurajen
kaust.authorRayapuram, Nagananden
kaust.authorRamirez Prado, Juan Sebastianen
kaust.authorBenhamed, Moussaen
kaust.authorHirt, Heriberten
kaust.grant.numberCRG4en
All Items in KAUST are protected by copyright, with all rights reserved, unless otherwise indicated.