Fluorescent multiplex cell flow systems and methods

Handle URI:
http://hdl.handle.net/10754/625141
Title:
Fluorescent multiplex cell flow systems and methods
Authors:
Merzaban, Jasmeen ( 0000-0002-7276-2907 ) ; Abuelela, Ayman F.; Mohammad, Amal Jehad
Assignee:
King Abdullah University Of Science And Technology
Abstract:
Systems and methods are provided for simultaneously assaying cell adhesion or cell rolling for multiple cell specimens. One embodiment provides a system for assaying adhesion or cell rolling of multiple cell specimens that includes a confocal imaging system containing a parallel plate flow chamber, a pump in fluid communication with the parallel plate flow chamber via a flow chamber inlet line and a cell suspension in fluid communication with the parallel plate flow chamber via a flow chamber outlet line. The system also includes a laser scanning system in electronic communication with the confocal imaging system, and a computer in communication with the confocal imaging system and laser scanning system. In certain embodiments, the laser scanning system emits multiple electromagnetic wavelengths simultaneously it cause multiple fluorescent labels having different excitation wavelength maximums to fluoresce. The system can simultaneously capture real-time fluorescence images from at least seven cell specimens in the parallel plate flow chamber.
KAUST Department:
Biological, Environmental Sciences & Engineering Division
Issue Date:
1-Jun-2017
Submitted date:
2015-11-29
Type:
Patent
Application Number:
WO 2017089888 A1
Patent Status:
Published Application
Additional Links:
http://www.google.com/patents/WO2017089888A1; http://worldwide.espacenet.com/publicationDetails/biblio?CC=WO&NR=2017089888A1&KC=A1&FT=D
Appears in Collections:
Patents

Full metadata record

DC FieldValue Language
dc.contributor.authorMerzaban, Jasmeenen
dc.contributor.authorAbuelela, Ayman F.en
dc.contributor.authorMohammad, Amal Jehaden
dc.date.accessioned2017-07-03T10:14:52Z-
dc.date.available2017-07-03T10:14:52Z-
dc.date.issued2017-06-01-
dc.date.submitted2015-11-29-
dc.identifier.urihttp://hdl.handle.net/10754/625141-
dc.description.abstractSystems and methods are provided for simultaneously assaying cell adhesion or cell rolling for multiple cell specimens. One embodiment provides a system for assaying adhesion or cell rolling of multiple cell specimens that includes a confocal imaging system containing a parallel plate flow chamber, a pump in fluid communication with the parallel plate flow chamber via a flow chamber inlet line and a cell suspension in fluid communication with the parallel plate flow chamber via a flow chamber outlet line. The system also includes a laser scanning system in electronic communication with the confocal imaging system, and a computer in communication with the confocal imaging system and laser scanning system. In certain embodiments, the laser scanning system emits multiple electromagnetic wavelengths simultaneously it cause multiple fluorescent labels having different excitation wavelength maximums to fluoresce. The system can simultaneously capture real-time fluorescence images from at least seven cell specimens in the parallel plate flow chamber.en
dc.relation.urlhttp://www.google.com/patents/WO2017089888A1en
dc.relation.urlhttp://worldwide.espacenet.com/publicationDetails/biblio?CC=WO&NR=2017089888A1&KC=A1&FT=Den
dc.titleFluorescent multiplex cell flow systems and methodsen
dc.typePatenten
dc.contributor.departmentBiological, Environmental Sciences & Engineering Divisionen
dc.description.statusPublished Applicationen
dc.contributor.assigneeKing Abdullah University Of Science And Technologyen
dc.description.countryWorld Intellectual Property Organization (WIPO)en
dc.identifier.applicationnumberWO 2017089888 A1en
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