pH-Sensitive Amphiphilic Block-Copolymers for Transport and Controlled Release of Oxygen

Handle URI:
http://hdl.handle.net/10754/625089
Title:
pH-Sensitive Amphiphilic Block-Copolymers for Transport and Controlled Release of Oxygen
Authors:
Patil, Yogesh; Almahdali, Sarah; Vu, Khanh B.; Zapsas, Georgios; Hadjichristidis, Nikolaos ( 0000-0003-1442-1714 ) ; Rodionov, Valentin
Abstract:
Saturated fluorocarbons, their derivatives and emulsions are capable of dissolving anomalously high amounts of oxygen and other gases. The mechanistic aspects of this remarkable effect remain to be explored experimentally. Here, the synthesis of a library of amphiphilic fluorous block-copolymers incorporating different fluorinated monomers is described, and the capacity of these copolymers for oxygen transport in water is systematically investigated. The structure of the fluorous monomer employed was found to have a profound effect on both the oxygen-carrying capacity and the gas release kinetics of the polymer emulsions. Furthermore, the release of O2 from the polymer dispersions could be triggered by changing the pH of the solution. This is the first example of a polymer-based system for controlled release of a non-polar, non-covalently entrapped respiratory gas.
KAUST Department:
KAUST Catalysis Center (KCC); Physical Sciences and Engineering (PSE) Division
Citation:
Patil Y, Almahdali S, Vu KB, Zapsas G, Hadjichristidis N, et al. (2017) pH-Sensitive amphiphilic block-copolymers for transport and controlled release of oxygen. Polym Chem. Available: http://dx.doi.org/10.1039/c7py00679a.
Publisher:
Royal Society of Chemistry (RSC)
Journal:
Polym. Chem.
Issue Date:
31-May-2017
DOI:
10.1039/c7py00679a
Type:
Article
ISSN:
1759-9954; 1759-9962
Sponsors:
This research was supported by King Abdullah University of Science and Technology (KAUST).
Additional Links:
http://pubs.rsc.org/en/Content/ArticleLanding/2017/PY/C7PY00679A#!divAbstract
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; KAUST Catalysis Center (KCC)

Full metadata record

DC FieldValue Language
dc.contributor.authorPatil, Yogeshen
dc.contributor.authorAlmahdali, Sarahen
dc.contributor.authorVu, Khanh B.en
dc.contributor.authorZapsas, Georgiosen
dc.contributor.authorHadjichristidis, Nikolaosen
dc.contributor.authorRodionov, Valentinen
dc.date.accessioned2017-06-21T06:42:08Z-
dc.date.available2017-06-21T06:42:08Z-
dc.date.issued2017-05-31en
dc.identifier.citationPatil Y, Almahdali S, Vu KB, Zapsas G, Hadjichristidis N, et al. (2017) pH-Sensitive amphiphilic block-copolymers for transport and controlled release of oxygen. Polym Chem. Available: http://dx.doi.org/10.1039/c7py00679a.en
dc.identifier.issn1759-9954en
dc.identifier.issn1759-9962en
dc.identifier.doi10.1039/c7py00679aen
dc.identifier.urihttp://hdl.handle.net/10754/625089-
dc.description.abstractSaturated fluorocarbons, their derivatives and emulsions are capable of dissolving anomalously high amounts of oxygen and other gases. The mechanistic aspects of this remarkable effect remain to be explored experimentally. Here, the synthesis of a library of amphiphilic fluorous block-copolymers incorporating different fluorinated monomers is described, and the capacity of these copolymers for oxygen transport in water is systematically investigated. The structure of the fluorous monomer employed was found to have a profound effect on both the oxygen-carrying capacity and the gas release kinetics of the polymer emulsions. Furthermore, the release of O2 from the polymer dispersions could be triggered by changing the pH of the solution. This is the first example of a polymer-based system for controlled release of a non-polar, non-covalently entrapped respiratory gas.en
dc.description.sponsorshipThis research was supported by King Abdullah University of Science and Technology (KAUST).en
dc.publisherRoyal Society of Chemistry (RSC)en
dc.relation.urlhttp://pubs.rsc.org/en/Content/ArticleLanding/2017/PY/C7PY00679A#!divAbstracten
dc.titlepH-Sensitive Amphiphilic Block-Copolymers for Transport and Controlled Release of Oxygenen
dc.typeArticleen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.identifier.journalPolym. Chem.en
dc.contributor.institutionNTT Hi-Tech Institute, Nguyen Tat Thanh University, 298-300A Nguyen Tat Thanh Street, Ho Chi Minh City, Vietnamen
kaust.authorPatil, Yogeshen
kaust.authorAlmahdali, Sarahen
kaust.authorZapsas, Georgiosen
kaust.authorHadjichristidis, Nikolaosen
kaust.authorRodionov, Valentinen
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