Amide to Alkyne Interconversion via a Nickel/Copper-Catalyzed Deamidative Cross-Coupling of Aryl and Alkenyl Amides

Handle URI:
http://hdl.handle.net/10754/625075
Title:
Amide to Alkyne Interconversion via a Nickel/Copper-Catalyzed Deamidative Cross-Coupling of Aryl and Alkenyl Amides
Authors:
Srimontree, Watchara; Chatupheeraphat, Adisak; Liao, Hsuan-Hung; Rueping, Magnus ( 0000-0003-4580-5227 )
Abstract:
A nickel-catalyzed deamidative cross-coupling reaction of amides with terminal alkynes as coupling partners was disclosed. This newly developed methodology allows the direct interconversion of amides to alkynes and enables a facile route for C(sp2)-C(sp) bond formation in a straightforward and mild fashion.
KAUST Department:
KAUST Catalysis Center (KCC)
Citation:
Srimontree W, Chatupheeraphat A, Liao H-H, Rueping M (2017) Amide to Alkyne Interconversion via a Nickel/Copper-Catalyzed Deamidative Cross-Coupling of Aryl and Alkenyl Amides. Organic Letters 19: 3091–3094. Available: http://dx.doi.org/10.1021/acs.orglett.7b01194.
Publisher:
American Chemical Society (ACS)
Journal:
Organic Letters
Issue Date:
5-Jun-2017
DOI:
10.1021/acs.orglett.7b01194
Type:
Article
ISSN:
1523-7060; 1523-7052
Sponsors:
H.-H.L. acknowledges the DAAD for a doctoral fellowship.
Additional Links:
http://pubs.acs.org/doi/full/10.1021/acs.orglett.7b01194
Appears in Collections:
Articles; KAUST Catalysis Center (KCC)

Full metadata record

DC FieldValue Language
dc.contributor.authorSrimontree, Watcharaen
dc.contributor.authorChatupheeraphat, Adisaken
dc.contributor.authorLiao, Hsuan-Hungen
dc.contributor.authorRueping, Magnusen
dc.date.accessioned2017-06-21T06:42:07Z-
dc.date.available2017-06-21T06:42:07Z-
dc.date.issued2017-06-05en
dc.identifier.citationSrimontree W, Chatupheeraphat A, Liao H-H, Rueping M (2017) Amide to Alkyne Interconversion via a Nickel/Copper-Catalyzed Deamidative Cross-Coupling of Aryl and Alkenyl Amides. Organic Letters 19: 3091–3094. Available: http://dx.doi.org/10.1021/acs.orglett.7b01194.en
dc.identifier.issn1523-7060en
dc.identifier.issn1523-7052en
dc.identifier.doi10.1021/acs.orglett.7b01194en
dc.identifier.urihttp://hdl.handle.net/10754/625075-
dc.description.abstractA nickel-catalyzed deamidative cross-coupling reaction of amides with terminal alkynes as coupling partners was disclosed. This newly developed methodology allows the direct interconversion of amides to alkynes and enables a facile route for C(sp2)-C(sp) bond formation in a straightforward and mild fashion.en
dc.description.sponsorshipH.-H.L. acknowledges the DAAD for a doctoral fellowship.en
dc.publisherAmerican Chemical Society (ACS)en
dc.relation.urlhttp://pubs.acs.org/doi/full/10.1021/acs.orglett.7b01194en
dc.titleAmide to Alkyne Interconversion via a Nickel/Copper-Catalyzed Deamidative Cross-Coupling of Aryl and Alkenyl Amidesen
dc.typeArticleen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.identifier.journalOrganic Lettersen
dc.contributor.institutionInstitute of Organic Chemistry, RWTH Aachen University , Landoltweg 1, 52074 Aachen, Germany.en
kaust.authorRueping, Magnusen
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