Catalytic Intermolecular Cross-Couplings of Azides and LUMO-Activated Unsaturated Acyl Azoliums

Handle URI:
http://hdl.handle.net/10754/623804
Title:
Catalytic Intermolecular Cross-Couplings of Azides and LUMO-Activated Unsaturated Acyl Azoliums
Authors:
Li, Wenjun; Ajitha, Manjaly John; Lang, Ming; Huang, Kuo-Wei ( 0000-0003-1900-2658 ) ; Wang, Jian
Abstract:
An example for the catalytic synthesis of densely functionalized 1,2,3-triazoles through a LUMO activation mode has been developed. The protocol is enabled by intermolecular cross coupling reactions of azides with in situ-generated alpha,beta-unsaturated acyl azoliums. High yields and broad scope as well as the investigation of reaction mechanism are reported.
KAUST Department:
KAUST Catalysis Center (KCC); Physical Sciences and Engineering (PSE) Division
Citation:
Li W, Ajitha MJ, Lang M, Huang K-W, Wang J (2017) Catalytic Intermolecular Cross-Couplings of Azides and LUMO-Activated Unsaturated Acyl Azoliums. ACS Catalysis 7: 2139–2144. Available: http://dx.doi.org/10.1021/acscatal.6b03674.
Publisher:
American Chemical Society (ACS)
Journal:
ACS Catalysis
Issue Date:
15-Feb-2017
DOI:
10.1021/acscatal.6b03674
Type:
Article
ISSN:
2155-5435; 2155-5435
Sponsors:
Generous financial supports are provided by the National Natural Science Foundation of China (21672121, 21502043), the
Additional Links:
http://pubs.acs.org/doi/abs/10.1021/acscatal.6b03674
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; KAUST Catalysis Center (KCC)

Full metadata record

DC FieldValue Language
dc.contributor.authorLi, Wenjunen
dc.contributor.authorAjitha, Manjaly Johnen
dc.contributor.authorLang, Mingen
dc.contributor.authorHuang, Kuo-Weien
dc.contributor.authorWang, Jianen
dc.date.accessioned2017-05-31T11:23:06Z-
dc.date.available2017-05-31T11:23:06Z-
dc.date.issued2017-02-15en
dc.identifier.citationLi W, Ajitha MJ, Lang M, Huang K-W, Wang J (2017) Catalytic Intermolecular Cross-Couplings of Azides and LUMO-Activated Unsaturated Acyl Azoliums. ACS Catalysis 7: 2139–2144. Available: http://dx.doi.org/10.1021/acscatal.6b03674.en
dc.identifier.issn2155-5435en
dc.identifier.issn2155-5435en
dc.identifier.doi10.1021/acscatal.6b03674en
dc.identifier.urihttp://hdl.handle.net/10754/623804-
dc.description.abstractAn example for the catalytic synthesis of densely functionalized 1,2,3-triazoles through a LUMO activation mode has been developed. The protocol is enabled by intermolecular cross coupling reactions of azides with in situ-generated alpha,beta-unsaturated acyl azoliums. High yields and broad scope as well as the investigation of reaction mechanism are reported.en
dc.description.sponsorshipGenerous financial supports are provided by the National Natural Science Foundation of China (21672121, 21502043), theen
dc.publisherAmerican Chemical Society (ACS)en
dc.relation.urlhttp://pubs.acs.org/doi/abs/10.1021/acscatal.6b03674en
dc.subject1,2,3-triazolesen
dc.subjectazidesen
dc.subject1,3-dipolar cycloadditionen
dc.subjectorganocatalysisen
dc.subjectunsaturated acyl azoliumen
dc.titleCatalytic Intermolecular Cross-Couplings of Azides and LUMO-Activated Unsaturated Acyl Azoliumsen
dc.typeArticleen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.identifier.journalACS Catalysisen
dc.contributor.institutionSchool of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, Chinaen
kaust.authorAjitha, Manjaly Johnen
kaust.authorHuang, Kuo-Weien
All Items in KAUST are protected by copyright, with all rights reserved, unless otherwise indicated.