Transfer Hydrogenation: Employing a Simple, In Situ Prepared Catalytic System

Handle URI:
http://hdl.handle.net/10754/623471
Title:
Transfer Hydrogenation: Employing a Simple, In Situ Prepared Catalytic System
Authors:
Ang, Eleanor Pei Ling ( 0000-0002-0875-7783 )
Abstract:
Transfer hydrogenation has been recognized to be an important synthetic method in both academic and industrial research to obtain valuable products including alcohols. Transition metal catalysts based on precious metals, such as Ru, Rh and Ir, are typically employed for this process. In recent years, iron-based catalysts have attracted considerable attention as a greener and more sustainable alternative since iron is earth abundant, inexpensive and non-toxic. In this work, a combination of iron disulfide with chelating bipyridine ligand was found to be effective for the transfer hydrogenation of a variety of ketones to the corresponding alcohols in the presence of a simple base. It provided a convenient and economical way to conduct transfer hydrogenation. A plausible role of sulfide next to the metal center in facilitating the catalytic reaction is demonstrated.
Advisors:
Huang, Kuo-Wei ( 0000-0003-1900-2658 )
Committee Member:
Eppinger, Jorg ( 0000-0001-7886-7059 ) ; Lai, Zhiping ( 0000-0001-9555-6009 )
KAUST Department:
Physical Sciences and Engineering (PSE) Division
Program:
Chemical Sciences
Issue Date:
Apr-2017
Type:
Thesis
Appears in Collections:
Theses

Full metadata record

DC FieldValue Language
dc.contributor.advisorHuang, Kuo-Weien
dc.contributor.authorAng, Eleanor Pei Lingen
dc.date.accessioned2017-05-11T09:19:15Z-
dc.date.available2017-05-11T09:19:15Z-
dc.date.issued2017-04-
dc.identifier.urihttp://hdl.handle.net/10754/623471-
dc.description.abstractTransfer hydrogenation has been recognized to be an important synthetic method in both academic and industrial research to obtain valuable products including alcohols. Transition metal catalysts based on precious metals, such as Ru, Rh and Ir, are typically employed for this process. In recent years, iron-based catalysts have attracted considerable attention as a greener and more sustainable alternative since iron is earth abundant, inexpensive and non-toxic. In this work, a combination of iron disulfide with chelating bipyridine ligand was found to be effective for the transfer hydrogenation of a variety of ketones to the corresponding alcohols in the presence of a simple base. It provided a convenient and economical way to conduct transfer hydrogenation. A plausible role of sulfide next to the metal center in facilitating the catalytic reaction is demonstrated.en
dc.language.isoenen
dc.subjectTransfer hydrogenationen
dc.subjectReductionen
dc.subjectKetonesen
dc.subjectIron-catalyzeden
dc.subjectIn situen
dc.titleTransfer Hydrogenation: Employing a Simple, In Situ Prepared Catalytic Systemen
dc.typeThesisen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
thesis.degree.grantorKing Abdullah University of Science and Technologyen_GB
dc.contributor.committeememberEppinger, Jorgen
dc.contributor.committeememberLai, Zhipingen
thesis.degree.disciplineChemical Sciencesen
thesis.degree.nameMaster of Scienceen
dc.person.id146200en
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