A LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) for biological tissue impedance analysis and equivalent circuit modelling

Handle URI:
http://hdl.handle.net/10754/623245
Title:
A LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) for biological tissue impedance analysis and equivalent circuit modelling
Authors:
Bera, Tushar Kanti; Jampana, Nagaraju; Lubineau, Gilles ( 0000-0002-7370-6093 )
Abstract:
Under an alternating electrical signal, biological tissues produce a complex electrical bioimpedance that is a function of tissue composition and applied signal frequencies. By studying the bioimpedance spectra of biological tissues over a wide range of frequencies, we can noninvasively probe the physiological properties of these tissues to detect possible pathological conditions. Electrical impedance spectroscopy (EIS) can provide the spectra that are needed to calculate impedance parameters within a wide range of frequencies. Before impedance parameters can be calculated and tissue information extracted, impedance spectra should be processed and analyzed by a dedicated software program. National Instruments (NI) Inc. offers LabVIEW, a fast, portable, robust, user-friendly platform for designing dataanalyzing software. We developed a LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) to analyze the electrical impedance spectra for tissue characterization in medical, biomedical and biological applications. Here, we test, calibrate and evaluate the performance of LEBISDI on the impedance data obtained from simulation studies as well as the practical EIS experimentations conducted on electronic circuit element combinations and the biological tissue samples. We analyze the Nyquist plots obtained from the EIS measurements and compare the equivalent circuit parameters calculated by LEBISDI with the corresponding original circuit parameters to assess the accuracy of the program developed. Calibration studies show that LEBISDI not only interpreted the simulated and circuitelement data accurately, but also successfully interpreted tissues impedance data and estimated the capacitive and resistive components produced by the compositions biological cells. Finally, LEBISDI efficiently calculated and analyzed variation in bioimpedance parameters of different tissue compositions, health and temperatures. LEBISDI can also be used for human tissue impedance analysis for electrical impedance-based tissue characterization, health analysis and disease diagnosis.
KAUST Department:
King Abdullah University of Science and Technology (KAUST), COHMAS Laboratory, Thuwal, 23955-6900, , Saudi Arabia
Citation:
Bera, T. K., Nagaraju, J., & Lubineau, G. (2016). A LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) for biological tissue impedance analysis and equivalent circuit modelling. Journal of Electrical Bioimpedance, 7(1), 35. doi:10.5617/jeb.2978
Publisher:
University of Oslo Library
Journal:
Journal of Electrical Bioimpedance
Issue Date:
5-Dec-2016
DOI:
10.5617/jeb.2978
Type:
Article
ISSN:
1891-5469
Sponsors:
All the authors thank King Abdullah University of Science and Technology (KAUST), Saudi Arabia, and the Indian Institute of Science (IISc), Bangalore, India, for providing research facilities required to complete this work.
Additional Links:
http://www.journals.uio.no/index.php/bioimpedance/article/view/2978
Appears in Collections:
Articles

Full metadata record

DC FieldValue Language
dc.contributor.authorBera, Tushar Kantien
dc.contributor.authorJampana, Nagarajuen
dc.contributor.authorLubineau, Gillesen
dc.date.accessioned2017-04-17T11:33:46Z-
dc.date.available2017-04-17T11:33:46Z-
dc.date.issued2016-12-05en
dc.identifier.citationBera, T. K., Nagaraju, J., & Lubineau, G. (2016). A LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) for biological tissue impedance analysis and equivalent circuit modelling. Journal of Electrical Bioimpedance, 7(1), 35. doi:10.5617/jeb.2978en
dc.identifier.issn1891-5469en
dc.identifier.doi10.5617/jeb.2978en
dc.identifier.urihttp://hdl.handle.net/10754/623245-
dc.description.abstractUnder an alternating electrical signal, biological tissues produce a complex electrical bioimpedance that is a function of tissue composition and applied signal frequencies. By studying the bioimpedance spectra of biological tissues over a wide range of frequencies, we can noninvasively probe the physiological properties of these tissues to detect possible pathological conditions. Electrical impedance spectroscopy (EIS) can provide the spectra that are needed to calculate impedance parameters within a wide range of frequencies. Before impedance parameters can be calculated and tissue information extracted, impedance spectra should be processed and analyzed by a dedicated software program. National Instruments (NI) Inc. offers LabVIEW, a fast, portable, robust, user-friendly platform for designing dataanalyzing software. We developed a LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) to analyze the electrical impedance spectra for tissue characterization in medical, biomedical and biological applications. Here, we test, calibrate and evaluate the performance of LEBISDI on the impedance data obtained from simulation studies as well as the practical EIS experimentations conducted on electronic circuit element combinations and the biological tissue samples. We analyze the Nyquist plots obtained from the EIS measurements and compare the equivalent circuit parameters calculated by LEBISDI with the corresponding original circuit parameters to assess the accuracy of the program developed. Calibration studies show that LEBISDI not only interpreted the simulated and circuitelement data accurately, but also successfully interpreted tissues impedance data and estimated the capacitive and resistive components produced by the compositions biological cells. Finally, LEBISDI efficiently calculated and analyzed variation in bioimpedance parameters of different tissue compositions, health and temperatures. LEBISDI can also be used for human tissue impedance analysis for electrical impedance-based tissue characterization, health analysis and disease diagnosis.en
dc.description.sponsorshipAll the authors thank King Abdullah University of Science and Technology (KAUST), Saudi Arabia, and the Indian Institute of Science (IISc), Bangalore, India, for providing research facilities required to complete this work.en
dc.publisherUniversity of Oslo Libraryen
dc.relation.urlhttp://www.journals.uio.no/index.php/bioimpedance/article/view/2978en
dc.rightsThis journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.en
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/en
dc.subjectCurve Fittingen
dc.subjectElectrical Bioimpedanceen
dc.subjectElectrical Impedance Spectroscopy (EIS)en
dc.subjectEquivalent Circuit Modellingen
dc.subjectLabVIEW-Based Electrical Bioimpedance Spectroscopic Data Interpreter (LEBISDI)en
dc.subjectNyquist Plotsen
dc.titleA LabVIEW-based electrical bioimpedance spectroscopic data interpreter (LEBISDI) for biological tissue impedance analysis and equivalent circuit modellingen
dc.typeArticleen
dc.contributor.departmentKing Abdullah University of Science and Technology (KAUST), COHMAS Laboratory, Thuwal, 23955-6900, , Saudi Arabiaen
dc.identifier.journalJournal of Electrical Bioimpedanceen
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionDepartment of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore, 560012, , Indiaen
kaust.authorBera, Tushar Kantien
kaust.authorLubineau, Gillesen
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