Nanoplasmonic and Microfluidic Devices for Biological Sensing

Handle URI:
http://hdl.handle.net/10754/623189
Title:
Nanoplasmonic and Microfluidic Devices for Biological Sensing
Authors:
Perozziello, G.; Giugni, Andrea; Allione, Marco ( 0000-0003-0757-9791 ) ; Torre, Bruno; Das, Gobind ( 0000-0003-0942-681X ) ; Coluccio, M. L.; Marini, Monica ( 0000-0001-8182-5239 ) ; Tirinato, Luca ( 0000-0001-9826-2129 ) ; Moretti, Manola; Limongi, Tania; Candeloro, P.; Di Fabrizio, Enzo M. ( 0000-0001-5886-4678 )
Abstract:
In this chapter we report about recent advances on the development and application of 2D and 3D plasmonic nanostructures used for sensing of biological samples by Raman spectroscopy at unprecedented resolution of analysis. Besides, we explain how the integration of these nanodevices in a microfluidic apparatus can simplify the analysis of biological samples. In the first part we introduce and motivate the convenience of using nanoplasmonic enhancers and Raman spectroscopy for biological sensing, describing the phenomena and the current approaches to fabricate nanoplasmonic structures. In the second part, we explain how specific multi-element devices produce the optimal enhancement of the Raman scattering. We report cases where biological sensing of DNA was performed at few molecules level with nanometer spatial resolutions. Finally, we show an example of microfluidic device integrating plasmonic nanodevices to sort and drive biological samples, like living cells, towards the optical probe in order to obtain optimal conditions of analysis.
KAUST Department:
Physical Sciences and Engineering (PSE) Division; Biological and Environmental Sciences and Engineering (BESE) Division
Citation:
Perozziello G, Giugni A, Allione M, Torre B, Das G, et al. (2017) Nanoplasmonic and Microfluidic Devices for Biological Sensing. Nano-Optics: Principles Enabling Basic Research and Applications: 247–274. Available: http://dx.doi.org/10.1007/978-94-024-0850-8_12.
Publisher:
Springer Netherlands
Journal:
NATO Science for Peace and Security Series B: Physics and Biophysics
Issue Date:
16-Feb-2017
DOI:
10.1007/978-94-024-0850-8_12
Type:
Book Chapter
ISSN:
1874-6500; 1874-6535
Sponsors:
We acknowledge all contributors that contributed in this work from other institution, in particular the researchers from the previous Nanostructure Division at IIT (Italian Institute of Technology) in Genoa. We thank for the financial support the King Abdullah University of Science and Technology start-up fund and the Italian Minister of Health (projects nos. GR-2010-2320665 and GR-2010-2311677)
Additional Links:
http://link.springer.com/chapter/10.1007/978-94-024-0850-8_12
Appears in Collections:
Physical Sciences and Engineering (PSE) Division; Book Chapters; Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorPerozziello, G.en
dc.contributor.authorGiugni, Andreaen
dc.contributor.authorAllione, Marcoen
dc.contributor.authorTorre, Brunoen
dc.contributor.authorDas, Gobinden
dc.contributor.authorColuccio, M. L.en
dc.contributor.authorMarini, Monicaen
dc.contributor.authorTirinato, Lucaen
dc.contributor.authorMoretti, Manolaen
dc.contributor.authorLimongi, Taniaen
dc.contributor.authorCandeloro, P.en
dc.contributor.authorDi Fabrizio, Enzo M.en
dc.date.accessioned2017-04-13T11:51:00Z-
dc.date.available2017-04-13T11:51:00Z-
dc.date.issued2017-02-16en
dc.identifier.citationPerozziello G, Giugni A, Allione M, Torre B, Das G, et al. (2017) Nanoplasmonic and Microfluidic Devices for Biological Sensing. Nano-Optics: Principles Enabling Basic Research and Applications: 247–274. Available: http://dx.doi.org/10.1007/978-94-024-0850-8_12.en
dc.identifier.issn1874-6500en
dc.identifier.issn1874-6535en
dc.identifier.doi10.1007/978-94-024-0850-8_12en
dc.identifier.urihttp://hdl.handle.net/10754/623189-
dc.description.abstractIn this chapter we report about recent advances on the development and application of 2D and 3D plasmonic nanostructures used for sensing of biological samples by Raman spectroscopy at unprecedented resolution of analysis. Besides, we explain how the integration of these nanodevices in a microfluidic apparatus can simplify the analysis of biological samples. In the first part we introduce and motivate the convenience of using nanoplasmonic enhancers and Raman spectroscopy for biological sensing, describing the phenomena and the current approaches to fabricate nanoplasmonic structures. In the second part, we explain how specific multi-element devices produce the optimal enhancement of the Raman scattering. We report cases where biological sensing of DNA was performed at few molecules level with nanometer spatial resolutions. Finally, we show an example of microfluidic device integrating plasmonic nanodevices to sort and drive biological samples, like living cells, towards the optical probe in order to obtain optimal conditions of analysis.en
dc.description.sponsorshipWe acknowledge all contributors that contributed in this work from other institution, in particular the researchers from the previous Nanostructure Division at IIT (Italian Institute of Technology) in Genoa. We thank for the financial support the King Abdullah University of Science and Technology start-up fund and the Italian Minister of Health (projects nos. GR-2010-2320665 and GR-2010-2311677)en
dc.publisherSpringer Netherlandsen
dc.relation.urlhttp://link.springer.com/chapter/10.1007/978-94-024-0850-8_12en
dc.rightsThe final publication is available at Springer via http://dx.doi.org/10.1007/978-94-024-0850-8_12en
dc.titleNanoplasmonic and Microfluidic Devices for Biological Sensingen
dc.typeBook Chapteren
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.identifier.journalNATO Science for Peace and Security Series B: Physics and Biophysicsen
dc.eprint.versionPost-printen
dc.contributor.institutionBionem Lab, Departement of Experimental Clinics, Campus “Salvatore Venuta”, University Magna Graecia, 88100 Germaneto-Catanzaro, Italyen
kaust.authorGiugni, Andreaen
kaust.authorAllione, Marcoen
kaust.authorTorre, Brunoen
kaust.authorDas, Gobinden
kaust.authorMarini, Monicaen
kaust.authorTirinato, Lucaen
kaust.authorMoretti, Manolaen
kaust.authorLimongi, Taniaen
kaust.authorDi Fabrizio, Enzo M.en
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