Folding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imaging

Handle URI:
http://hdl.handle.net/10754/623137
Title:
Folding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imaging
Authors:
Liu, Yijing; He, Jie; Yang, Kuikun; Yi, Chenglin; Liu, Yi; Nie, Liming; Khashab, Niveen M. ( 0000-0003-2728-0666 ) ; Chen, Xiaoyuan; Nie, Zhihong
Abstract:
The stepwise self-assembly of hollow plasmonic vesicles with vesicular membranes containing strings of gold nanoparticles (NPs) is reported. The formation of chain vesicles can be controlled by tuning the density of the polymer ligands on the surface of the gold NPs. The strong absorption of the chain vesicles in the near-infrared (NIR) region leads to a much higher efficiency in photoacoustic (PA) imaging than for non-chain vesicles. The chain vesicles were further employed for the encapsulation of drugs and the NIR light triggered release of payloads. This work not only offers a new platform for controlling the hierarchical self-assembly of NPs, but also demonstrates that the physical properties of the materials can be tailored by controlling the spatial arrangement of NPs within assemblies to achieve a better performance in biomedical applications.
KAUST Department:
Advanced Membranes and Porous Materials Research Center; Chemical Science Program; Smart Hybrid Materials (SHMs) lab
Citation:
Liu Y, He J, Yang K, Yi C, Liu Y, et al. (2015) Folding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imaging. Angewandte Chemie International Edition 54: 15809–15812. Available: http://dx.doi.org/10.1002/anie.201508616.
Publisher:
Wiley-Blackwell
Journal:
Angewandte Chemie International Edition
Issue Date:
11-Nov-2015
DOI:
10.1002/anie.201508616; 10.1002/ange.201508616
Type:
Article
ISSN:
1433-7851
Sponsors:
This work was funded by a National Science Foundation (NSF) CAREER award (DMR-1255377), the ACS Petroleum Research Fund (PRF 53461-DNI7), a 3M non-tenured faculty award, and the Intramural Research Program of the National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health. We acknowledge support by the Maryland NanoCenter and its NispLab.
Appears in Collections:
Articles; Advanced Membranes and Porous Materials Research Center; Controlled Release and Delivery Laboratory; Chemical Science Program

Full metadata record

DC FieldValue Language
dc.contributor.authorLiu, Yijingen
dc.contributor.authorHe, Jieen
dc.contributor.authorYang, Kuikunen
dc.contributor.authorYi, Chenglinen
dc.contributor.authorLiu, Yien
dc.contributor.authorNie, Limingen
dc.contributor.authorKhashab, Niveen M.en
dc.contributor.authorChen, Xiaoyuanen
dc.contributor.authorNie, Zhihongen
dc.date.accessioned2017-04-13T11:50:56Z-
dc.date.available2017-04-13T11:50:56Z-
dc.date.issued2015-11-11en
dc.identifier.citationLiu Y, He J, Yang K, Yi C, Liu Y, et al. (2015) Folding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imaging. Angewandte Chemie International Edition 54: 15809–15812. Available: http://dx.doi.org/10.1002/anie.201508616.en
dc.identifier.issn1433-7851en
dc.identifier.doi10.1002/anie.201508616en
dc.identifier.doi10.1002/ange.201508616en
dc.identifier.urihttp://hdl.handle.net/10754/623137-
dc.description.abstractThe stepwise self-assembly of hollow plasmonic vesicles with vesicular membranes containing strings of gold nanoparticles (NPs) is reported. The formation of chain vesicles can be controlled by tuning the density of the polymer ligands on the surface of the gold NPs. The strong absorption of the chain vesicles in the near-infrared (NIR) region leads to a much higher efficiency in photoacoustic (PA) imaging than for non-chain vesicles. The chain vesicles were further employed for the encapsulation of drugs and the NIR light triggered release of payloads. This work not only offers a new platform for controlling the hierarchical self-assembly of NPs, but also demonstrates that the physical properties of the materials can be tailored by controlling the spatial arrangement of NPs within assemblies to achieve a better performance in biomedical applications.en
dc.description.sponsorshipThis work was funded by a National Science Foundation (NSF) CAREER award (DMR-1255377), the ACS Petroleum Research Fund (PRF 53461-DNI7), a 3M non-tenured faculty award, and the Intramural Research Program of the National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health. We acknowledge support by the Maryland NanoCenter and its NispLab.en
dc.publisherWiley-Blackwellen
dc.subjectBlock copolymersen
dc.subjectGold nanoparticlesen
dc.subjectPhotoacoustic imagingen
dc.subjectSelf-assemblyen
dc.subjectVesiclesen
dc.titleFolding Up of Gold Nanoparticle Strings into Plasmonic Vesicles for Enhanced Photoacoustic Imagingen
dc.typeArticleen
dc.contributor.departmentAdvanced Membranes and Porous Materials Research Centeren
dc.contributor.departmentChemical Science Programen
dc.contributor.departmentSmart Hybrid Materials (SHMs) laben
dc.identifier.journalAngewandte Chemie International Editionen
dc.contributor.institutionDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD, United Statesen
dc.contributor.institutionLaboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health, United Statesen
kaust.authorKhashab, Niveen M.en
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