Chromatin architecture: A new dimension in the dynamic control of gene expression

Handle URI:
http://hdl.handle.net/10754/622885
Title:
Chromatin architecture: A new dimension in the dynamic control of gene expression
Authors:
Ramirez Prado, Juan Sebastian; Rodriguez-Granados, Natalia Yaneth; Ariel, Federico; Raynaud, Cécile; Benhamed, Moussa
Abstract:
As the most recent evidence of eukaryotic cell complexity, genome architecture has astounded the scientific community and prompted a variety of technical and cognitive challenges. Several technologies have emerged and evidenced the integration of chromatin packaging and topology, epigenetic processes, and transcription for the pertinent regulation of gene expression. In the present addendum we present and discuss some of our recent research, directed toward the holistic comprehension of the processes by which plants respond to environmental and developmental stimuli. We propose that the study of genome topology and genomic interactions is essential for the understanding of the molecular mechanisms behind a phenotype. Even though our knowledge and understanding of genome architecture and hierarchy has improved substantially in the last few years -in Arabidopsis and other eukaryotes -, there is still a long way ahead in this relatively new field of study. For this, it is necessary to take advantage of the high resolution of the emerging available techniques, and perform integrative approaches with which it will be possible to depict the role of chromatin architecture in the regulation of transcription and ultimately, physiological processes.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division
Citation:
Ramirez-Prado JS, Rodriguez-Granados NY, Ariel F, Raynaud C, Benhamed M (2016) Chromatin architecture: A new dimension in the dynamic control of gene expression. Plant Signaling & Behavior 11: e1232224. Available: http://dx.doi.org/10.1080/15592324.2016.1232224.
Publisher:
Informa UK Limited
Journal:
Plant Signaling & Behavior
Issue Date:
10-Sep-2016
DOI:
10.1080/15592324.2016.1232224
Type:
Article
ISSN:
1559-2324
Additional Links:
http://www.tandfonline.com/doi/full/10.1080/15592324.2016.1232224
Appears in Collections:
Articles; Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorRamirez Prado, Juan Sebastianen
dc.contributor.authorRodriguez-Granados, Natalia Yanethen
dc.contributor.authorAriel, Federicoen
dc.contributor.authorRaynaud, Cécileen
dc.contributor.authorBenhamed, Moussaen
dc.date.accessioned2017-02-15T08:32:14Z-
dc.date.available2017-02-15T08:32:14Z-
dc.date.issued2016-09-10en
dc.identifier.citationRamirez-Prado JS, Rodriguez-Granados NY, Ariel F, Raynaud C, Benhamed M (2016) Chromatin architecture: A new dimension in the dynamic control of gene expression. Plant Signaling & Behavior 11: e1232224. Available: http://dx.doi.org/10.1080/15592324.2016.1232224.en
dc.identifier.issn1559-2324en
dc.identifier.doi10.1080/15592324.2016.1232224en
dc.identifier.urihttp://hdl.handle.net/10754/622885-
dc.description.abstractAs the most recent evidence of eukaryotic cell complexity, genome architecture has astounded the scientific community and prompted a variety of technical and cognitive challenges. Several technologies have emerged and evidenced the integration of chromatin packaging and topology, epigenetic processes, and transcription for the pertinent regulation of gene expression. In the present addendum we present and discuss some of our recent research, directed toward the holistic comprehension of the processes by which plants respond to environmental and developmental stimuli. We propose that the study of genome topology and genomic interactions is essential for the understanding of the molecular mechanisms behind a phenotype. Even though our knowledge and understanding of genome architecture and hierarchy has improved substantially in the last few years -in Arabidopsis and other eukaryotes -, there is still a long way ahead in this relatively new field of study. For this, it is necessary to take advantage of the high resolution of the emerging available techniques, and perform integrative approaches with which it will be possible to depict the role of chromatin architecture in the regulation of transcription and ultimately, physiological processes.en
dc.publisherInforma UK Limiteden
dc.relation.urlhttp://www.tandfonline.com/doi/full/10.1080/15592324.2016.1232224en
dc.subjectGene Expressionen
dc.subjectGene Loopsen
dc.subjectChromatin Architectureen
dc.subjectLncrnasen
dc.subjectGenome Topologyen
dc.subjectGenomic Interactionsen
dc.titleChromatin architecture: A new dimension in the dynamic control of gene expressionen
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.identifier.journalPlant Signaling & Behavioren
dc.contributor.institutionInstitute of Plant Sciences Paris-Saclay (IPS2), CNRS, INRA, University Paris-Sud, University of Evry, University Paris-Diderot, Sorbonne Paris-Cite, University of Paris-Saclay , Batiment, Orsay , France.en
dc.contributor.institutionInstituto de Agrobiotecnología del Litoral, CONICET, Universidad Nacional del Litoral , 3000 Santa Fe , Argentina.en
kaust.authorRamirez Prado, Juan Sebastianen
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