Quorum Sensing and the Use of Quorum Quenchers as Natural Biocides to Inhibit Sulfate-Reducing Bacteria

Handle URI:
http://hdl.handle.net/10754/622844
Title:
Quorum Sensing and the Use of Quorum Quenchers as Natural Biocides to Inhibit Sulfate-Reducing Bacteria
Authors:
Scarascia, Giantommaso ( 0000-0003-3202-9871 ) ; Wang, Tiannyu; Hong, Pei Ying
Abstract:
Sulfate-reducing bacteria (SRB) are one of the main protagonist groups of biocorrosion in the seawater environment. Given their principal role in biocorrosion, it remains a crucial task to develop strategies to reduce the abundance of SRBs. Conventional approaches include the use of biocides and antibiotics, which can impose health, safety, and environmental concerns. This review examines an alternative approach to this problem. This is achieved by reviewing the role of quorum sensing (QS) in SRB populations and its impact on the biofilm formation process. Genome databases of SRBs are mined to look for putative QS systems and homologous protein sequences representative of autoinducer receptors or synthases. Subsequently, this review puts forward the potential use of quorum quenchers as natural biocides against SRBs and outlines the potential strategies for the implementation of this approach.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division; Water Desalination and Reuse Research Center (WDRC)
Citation:
Scarascia G, Wang T, Hong P-Y (2016) Quorum Sensing and the Use of Quorum Quenchers as Natural Biocides to Inhibit Sulfate-Reducing Bacteria. Antibiotics 5: 39. Available: http://dx.doi.org/10.3390/antibiotics5040039.
Publisher:
MDPI AG
Journal:
Antibiotics
KAUST Grant Number:
BAS/1/1033-01-01
Issue Date:
15-Dec-2016
DOI:
10.3390/antibiotics5040039
Type:
Article
ISSN:
2079-6382
Sponsors:
The work detailed in this review and the costs to publish in open access are both funded by King Abdullah University of Science and Technology (KAUST) baseline funding BAS/1/1033-01-01 awarded to Pei-Ying Hong. The authors would like to express gratitude to Moustapha Harb for proofreading and editing the review.
Additional Links:
http://www.mdpi.com/2079-6382/5/4/39
Appears in Collections:
Articles; Water Desalination and Reuse Research Center (WDRC); Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorScarascia, Giantommasoen
dc.contributor.authorWang, Tiannyuen
dc.contributor.authorHong, Pei Yingen
dc.date.accessioned2017-02-07T08:28:38Z-
dc.date.available2017-02-07T08:28:38Z-
dc.date.issued2016-12-15en
dc.identifier.citationScarascia G, Wang T, Hong P-Y (2016) Quorum Sensing and the Use of Quorum Quenchers as Natural Biocides to Inhibit Sulfate-Reducing Bacteria. Antibiotics 5: 39. Available: http://dx.doi.org/10.3390/antibiotics5040039.en
dc.identifier.issn2079-6382en
dc.identifier.doi10.3390/antibiotics5040039en
dc.identifier.urihttp://hdl.handle.net/10754/622844-
dc.description.abstractSulfate-reducing bacteria (SRB) are one of the main protagonist groups of biocorrosion in the seawater environment. Given their principal role in biocorrosion, it remains a crucial task to develop strategies to reduce the abundance of SRBs. Conventional approaches include the use of biocides and antibiotics, which can impose health, safety, and environmental concerns. This review examines an alternative approach to this problem. This is achieved by reviewing the role of quorum sensing (QS) in SRB populations and its impact on the biofilm formation process. Genome databases of SRBs are mined to look for putative QS systems and homologous protein sequences representative of autoinducer receptors or synthases. Subsequently, this review puts forward the potential use of quorum quenchers as natural biocides against SRBs and outlines the potential strategies for the implementation of this approach.en
dc.description.sponsorshipThe work detailed in this review and the costs to publish in open access are both funded by King Abdullah University of Science and Technology (KAUST) baseline funding BAS/1/1033-01-01 awarded to Pei-Ying Hong. The authors would like to express gratitude to Moustapha Harb for proofreading and editing the review.en
dc.publisherMDPI AGen
dc.relation.urlhttp://www.mdpi.com/2079-6382/5/4/39en
dc.rightsThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectBiocorrosionen
dc.subjectBiofilmen
dc.subjectBiofoulingen
dc.subjectDissimilatory sulfate reductionen
dc.subjectExtremophilesen
dc.titleQuorum Sensing and the Use of Quorum Quenchers as Natural Biocides to Inhibit Sulfate-Reducing Bacteriaen
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.contributor.departmentWater Desalination and Reuse Research Center (WDRC)en
dc.identifier.journalAntibioticsen
dc.eprint.versionPublisher's Version/PDFen
kaust.authorScarascia, Giantommasoen
kaust.authorWang, Tiannyuen
kaust.authorHong, Pei Yingen
kaust.grant.numberBAS/1/1033-01-01en
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