Visible-Light Photoredox-Catalyzed Giese Reaction: Decarboxylative Addition of Amino Acid Derived α-Amino Radicals to Electron-Deficient Olefins

Handle URI:
http://hdl.handle.net/10754/621688
Title:
Visible-Light Photoredox-Catalyzed Giese Reaction: Decarboxylative Addition of Amino Acid Derived α-Amino Radicals to Electron-Deficient Olefins
Authors:
Millet, Anthony; Lefebvre, Quentin; Rueping, Magnus ( 0000-0003-4580-5227 )
Abstract:
A tin- and halide-free, visible-light photoredox-catalyzed Giese reaction was developed. Primary and secondary α-amino radicals were generated readily from amino acids in the presence of catalytic amounts of an iridium photocatalyst. The reactivity of the α-amino radicals has been evaluated for the functionalization of a variety of activated olefins. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
KAUST Department:
KAUST Catalysis Center (KCC)
Citation:
Millet A, Lefebvre Q, Rueping M (2016) Visible-Light Photoredox-Catalyzed Giese Reaction: Decarboxylative Addition of Amino Acid Derived α-Amino Radicals to Electron-Deficient Olefins. Chemistry - A European Journal 22: 13464–13468. Available: http://dx.doi.org/10.1002/chem.201602257.
Publisher:
Wiley-Blackwell
Journal:
Chemistry - A European Journal
Issue Date:
20-Jun-2016
DOI:
10.1002/chem.201602257
Type:
Article
ISSN:
0947-6539
Sponsors:
European Research Council; European Union[617044]
Appears in Collections:
Articles; KAUST Catalysis Center (KCC)

Full metadata record

DC FieldValue Language
dc.contributor.authorMillet, Anthonyen
dc.contributor.authorLefebvre, Quentinen
dc.contributor.authorRueping, Magnusen
dc.date.accessioned2016-11-03T13:22:48Z-
dc.date.available2016-11-03T13:22:48Z-
dc.date.issued2016-06-20en
dc.identifier.citationMillet A, Lefebvre Q, Rueping M (2016) Visible-Light Photoredox-Catalyzed Giese Reaction: Decarboxylative Addition of Amino Acid Derived α-Amino Radicals to Electron-Deficient Olefins. Chemistry - A European Journal 22: 13464–13468. Available: http://dx.doi.org/10.1002/chem.201602257.en
dc.identifier.issn0947-6539en
dc.identifier.doi10.1002/chem.201602257en
dc.identifier.urihttp://hdl.handle.net/10754/621688-
dc.description.abstractA tin- and halide-free, visible-light photoredox-catalyzed Giese reaction was developed. Primary and secondary α-amino radicals were generated readily from amino acids in the presence of catalytic amounts of an iridium photocatalyst. The reactivity of the α-amino radicals has been evaluated for the functionalization of a variety of activated olefins. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheimen
dc.description.sponsorshipEuropean Research Councilen
dc.description.sponsorshipEuropean Union[617044]en
dc.publisherWiley-Blackwellen
dc.subjectamino aciden
dc.subjectdecarboxylationen
dc.subjectheterocyclesen
dc.subjectphotoredox catalysisen
dc.titleVisible-Light Photoredox-Catalyzed Giese Reaction: Decarboxylative Addition of Amino Acid Derived α-Amino Radicals to Electron-Deficient Olefinsen
dc.typeArticleen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.identifier.journalChemistry - A European Journalen
dc.contributor.institutionInstitute of Organic Chemistry; RWTH Aachen; Landoltweg 1 52074 Aachen Germanyen
kaust.authorRueping, Magnusen
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