Comparison of capacitive and radio frequency resonator sensors for monitoring parallelized droplet microfluidic production

Handle URI:
http://hdl.handle.net/10754/621514
Title:
Comparison of capacitive and radio frequency resonator sensors for monitoring parallelized droplet microfluidic production
Authors:
Conchouso Gonzalez, David ( 0000-0002-9788-0977 ) ; McKerricher, Garret ( 0000-0002-6920-842X ) ; Carreno, Armando Arpys Arevalo ( 0000-0001-9446-3310 ) ; Castro, David; Shamim, Atif ( 0000-0002-4207-4740 ) ; Foulds, Ian G.
Abstract:
Scaled-up production of microfluidic droplets, through the parallelization of hundreds of droplet generators, has received a lot of attention to bring novel multiphase microfluidics research to industrial applications. However, apart from droplet generation, other significant challenges relevant to this goal have never been discussed. Examples include monitoring systems, high-throughput processing of droplets and quality control procedures among others. In this paper, we present and compare capacitive and radio frequency (RF) resonator sensors as two candidates that can measure the dielectric properties of emulsions in microfluidic channels. By placing several of these sensors in a parallelization device, the stability of the droplet generation at different locations can be compared, and potential malfunctions can be detected. This strategy enables for the first time the monitoring of scaled-up microfluidic droplet production. Both sensors were prototyped and characterized using emulsions with droplets of 100-150 μm in diameter, which were generated in parallelization devices at water-in-oil volume fractions (φ) between 11.1% and 33.3%.Using these sensors, we were able to measure accurately increments as small as 2.4% in the water volume fraction of the emulsions. Although both methods rely on the dielectric properties of the emulsions, the main advantage of the RF resonator sensors is the fact that they can be designed to resonate at multiple frequencies of the broadband transmission line. Consequently with careful design, two or more sensors can be parallelized and read out by a single signal. Finally, a comparison between these sensors based on their sensitivity, readout cost and simplicity, and design flexibility is also discussed. © 2016 The Royal Society of Chemistry.
KAUST Department:
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division; Electromechanical Microsystems & Polymer Integration Research Lab (EMPIRe); Integrated Microwave Packaging Antennas and Circuits Technology (IMPACT) Lab
Citation:
Conchouso D, McKerricher G, Arevalo A, Castro D, Shamim A, et al. (2016) Comparison of capacitive and radio frequency resonator sensors for monitoring parallelized droplet microfluidic production. Lab Chip 16: 3210–3219. Available: http://dx.doi.org/10.1039/c6lc00693k.
Publisher:
Royal Society of Chemistry (RSC)
Journal:
Lab Chip
Issue Date:
28-Jun-2016
DOI:
10.1039/c6lc00693k
Type:
Article
ISSN:
1473-0197; 1473-0189
Appears in Collections:
Articles; Integrated Microwave Packaging Antennas and Circuits Technology (IMPACT) Lab; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorConchouso Gonzalez, Daviden
dc.contributor.authorMcKerricher, Garreten
dc.contributor.authorCarreno, Armando Arpys Arevaloen
dc.contributor.authorCastro, Daviden
dc.contributor.authorShamim, Atifen
dc.contributor.authorFoulds, Ian G.en
dc.date.accessioned2016-11-03T08:31:09Z-
dc.date.available2016-11-03T08:31:09Z-
dc.date.issued2016-06-28en
dc.identifier.citationConchouso D, McKerricher G, Arevalo A, Castro D, Shamim A, et al. (2016) Comparison of capacitive and radio frequency resonator sensors for monitoring parallelized droplet microfluidic production. Lab Chip 16: 3210–3219. Available: http://dx.doi.org/10.1039/c6lc00693k.en
dc.identifier.issn1473-0197en
dc.identifier.issn1473-0189en
dc.identifier.doi10.1039/c6lc00693ken
dc.identifier.urihttp://hdl.handle.net/10754/621514-
dc.description.abstractScaled-up production of microfluidic droplets, through the parallelization of hundreds of droplet generators, has received a lot of attention to bring novel multiphase microfluidics research to industrial applications. However, apart from droplet generation, other significant challenges relevant to this goal have never been discussed. Examples include monitoring systems, high-throughput processing of droplets and quality control procedures among others. In this paper, we present and compare capacitive and radio frequency (RF) resonator sensors as two candidates that can measure the dielectric properties of emulsions in microfluidic channels. By placing several of these sensors in a parallelization device, the stability of the droplet generation at different locations can be compared, and potential malfunctions can be detected. This strategy enables for the first time the monitoring of scaled-up microfluidic droplet production. Both sensors were prototyped and characterized using emulsions with droplets of 100-150 μm in diameter, which were generated in parallelization devices at water-in-oil volume fractions (φ) between 11.1% and 33.3%.Using these sensors, we were able to measure accurately increments as small as 2.4% in the water volume fraction of the emulsions. Although both methods rely on the dielectric properties of the emulsions, the main advantage of the RF resonator sensors is the fact that they can be designed to resonate at multiple frequencies of the broadband transmission line. Consequently with careful design, two or more sensors can be parallelized and read out by a single signal. Finally, a comparison between these sensors based on their sensitivity, readout cost and simplicity, and design flexibility is also discussed. © 2016 The Royal Society of Chemistry.en
dc.publisherRoyal Society of Chemistry (RSC)en
dc.titleComparison of capacitive and radio frequency resonator sensors for monitoring parallelized droplet microfluidic productionen
dc.typeArticleen
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Divisionen
dc.contributor.departmentElectromechanical Microsystems & Polymer Integration Research Lab (EMPIRe)en
dc.contributor.departmentIntegrated Microwave Packaging Antennas and Circuits Technology (IMPACT) Laben
dc.identifier.journalLab Chipen
dc.contributor.institutionUniversity of British Columbia, Okanagan, Canadaen
kaust.authorConchouso Gonzalez, Daviden
kaust.authorMcKerricher, Garreten
kaust.authorCarreno, Armando Arpys Arevaloen
kaust.authorCastro, Daviden
kaust.authorShamim, Atifen
kaust.authorFoulds, Ian G.en
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