The genetics of an early Neolithic pastoralist from the Zagros, Iran

Handle URI:
http://hdl.handle.net/10754/620938
Title:
The genetics of an early Neolithic pastoralist from the Zagros, Iran
Authors:
Gallego-Llorente, M.; Connell, S.; Jones, E. R.; Merrett, D. C.; Jeon, Y.; Eriksson, Anders ( 0000-0003-3436-3726 ) ; Siska, V.; Gamba, C.; Meiklejohn, C.; Beyer, R.; Jeon, S.; Cho, Y. S.; Hofreiter, M.; Bhak, J.; Manica, A.; Pinhasi, R.
Abstract:
The agricultural transition profoundly changed human societies. We sequenced and analysed the first genome (1.39x) of an early Neolithic woman from Ganj Dareh, in the Zagros Mountains of Iran, a site with early evidence for an economy based on goat herding, ca. 10,000 BP. We show that Western Iran was inhabited by a population genetically most similar to hunter-gatherers from the Caucasus, but distinct from the Neolithic Anatolian people who later brought food production into Europe. The inhabitants of Ganj Dareh made little direct genetic contribution to modern European populations, suggesting those of the Central Zagros were somewhat isolated from other populations of the Fertile Crescent. Runs of homozygosity are of a similar length to those from Neolithic farmers, and shorter than those of Caucasus and Western Hunter-Gatherers, suggesting that the inhabitants of Ganj Dareh did not undergo the large population bottleneck suffered by their northern neighbours. While some degree of cultural diffusion between Anatolia, Western Iran and other neighbouring regions is possible, the genetic dissimilarity between early Anatolian farmers and the inhabitants of Ganj Dareh supports a model in which Neolithic societies in these areas were distinct.
KAUST Department:
Division of Biological and Environmental Sciences & Engineering
Citation:
Gallego-Llorente M, Connell S, Jones ER, Merrett DC, Jeon Y, et al. (2016) The genetics of an early Neolithic pastoralist from the Zagros, Iran. Scientific Reports 6: 31326. Available: http://dx.doi.org/10.1038/srep31326.
Publisher:
Springer Nature
Journal:
Scientific Reports
Issue Date:
9-Aug-2016
DOI:
10.1038/srep31326
Type:
Article
ISSN:
2045-2322
Sponsors:
A.M. was supported by ERC Consolidator Grant 647787 ‘LocalAdaptation’; R.P. by ERC Starting Grant: ERC- 2010-StG 26344 (“ADNABIOARC”); M.H. by ERC Consolidator Grant 310763 ‘GeneFlow’; C.G. was supported by the Irish Research Council for Humanities and Social Sciences (IRCHSS) ERC Support Programme and the Marie-Curie Intra-European Fellowships (FP7-IEF-328024); S.C. was supported by the Irish Research Council for Humanities and Social Sciences (IRCHSS) ERC Support Programme; J.B. was supported by the 2014 Research fund (1.140077.01) of Ulsan National Institute of Science & Technology (UNIST) and Geromics internal research funding; J.B. and Y.S.C. were supported by the Research Fund (14-BR-SS-03) of Civil-Military Technology Cooperation Program; R.B. was supported by ERC Consolidator Grant 617627 “ADaPt”; and M.G. by a BBSRC DTP studentship.
Additional Links:
http://www.nature.com/articles/srep31326
Appears in Collections:
Articles

Full metadata record

DC FieldValue Language
dc.contributor.authorGallego-Llorente, M.en
dc.contributor.authorConnell, S.en
dc.contributor.authorJones, E. R.en
dc.contributor.authorMerrett, D. C.en
dc.contributor.authorJeon, Y.en
dc.contributor.authorEriksson, Andersen
dc.contributor.authorSiska, V.en
dc.contributor.authorGamba, C.en
dc.contributor.authorMeiklejohn, C.en
dc.contributor.authorBeyer, R.en
dc.contributor.authorJeon, S.en
dc.contributor.authorCho, Y. S.en
dc.contributor.authorHofreiter, M.en
dc.contributor.authorBhak, J.en
dc.contributor.authorManica, A.en
dc.contributor.authorPinhasi, R.en
dc.date.accessioned2016-10-12T09:15:15Z-
dc.date.available2016-10-12T09:15:15Z-
dc.date.issued2016-08-09en
dc.identifier.citationGallego-Llorente M, Connell S, Jones ER, Merrett DC, Jeon Y, et al. (2016) The genetics of an early Neolithic pastoralist from the Zagros, Iran. Scientific Reports 6: 31326. Available: http://dx.doi.org/10.1038/srep31326.en
dc.identifier.issn2045-2322en
dc.identifier.doi10.1038/srep31326en
dc.identifier.urihttp://hdl.handle.net/10754/620938-
dc.description.abstractThe agricultural transition profoundly changed human societies. We sequenced and analysed the first genome (1.39x) of an early Neolithic woman from Ganj Dareh, in the Zagros Mountains of Iran, a site with early evidence for an economy based on goat herding, ca. 10,000 BP. We show that Western Iran was inhabited by a population genetically most similar to hunter-gatherers from the Caucasus, but distinct from the Neolithic Anatolian people who later brought food production into Europe. The inhabitants of Ganj Dareh made little direct genetic contribution to modern European populations, suggesting those of the Central Zagros were somewhat isolated from other populations of the Fertile Crescent. Runs of homozygosity are of a similar length to those from Neolithic farmers, and shorter than those of Caucasus and Western Hunter-Gatherers, suggesting that the inhabitants of Ganj Dareh did not undergo the large population bottleneck suffered by their northern neighbours. While some degree of cultural diffusion between Anatolia, Western Iran and other neighbouring regions is possible, the genetic dissimilarity between early Anatolian farmers and the inhabitants of Ganj Dareh supports a model in which Neolithic societies in these areas were distinct.en
dc.description.sponsorshipA.M. was supported by ERC Consolidator Grant 647787 ‘LocalAdaptation’; R.P. by ERC Starting Grant: ERC- 2010-StG 26344 (“ADNABIOARC”); M.H. by ERC Consolidator Grant 310763 ‘GeneFlow’; C.G. was supported by the Irish Research Council for Humanities and Social Sciences (IRCHSS) ERC Support Programme and the Marie-Curie Intra-European Fellowships (FP7-IEF-328024); S.C. was supported by the Irish Research Council for Humanities and Social Sciences (IRCHSS) ERC Support Programme; J.B. was supported by the 2014 Research fund (1.140077.01) of Ulsan National Institute of Science & Technology (UNIST) and Geromics internal research funding; J.B. and Y.S.C. were supported by the Research Fund (14-BR-SS-03) of Civil-Military Technology Cooperation Program; R.B. was supported by ERC Consolidator Grant 617627 “ADaPt”; and M.G. by a BBSRC DTP studentship.en
dc.publisherSpringer Natureen
dc.relation.urlhttp://www.nature.com/articles/srep31326en
dc.rights© The Author(s) 2016. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/en
dc.titleThe genetics of an early Neolithic pastoralist from the Zagros, Iranen
dc.typeArticleen
dc.contributor.departmentDivision of Biological and Environmental Sciences & Engineeringen
dc.identifier.journalScientific Reportsen
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionDepartment of Zoology, University of Cambridge, Cambridge, CB2 3EJ, UKen
dc.contributor.institutionSchool of Archaeology and Earth Institute, University College Dublin, Belfield, Dublin 4, Irelanden
dc.contributor.institutionDepartment of Archaeology, Simon Fraser University, Burnaby, BC V5A 1S6, Canadaen
dc.contributor.institutionThe Genomics Institute, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Koreaen
dc.contributor.institutionDepartment of Biomedical Engineering, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Koreaen
dc.contributor.institutionCentre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5–7, Copenhagen 1350, Denmarken
dc.contributor.institutionDepartment of Anthropology, University of Winnipeg, Winnipeg, MB R3B 2E9, Canadaen
dc.contributor.institutionMcDonald Institute for Archaeological Research, University of Cambridge, Cambridge CB2 3ER, UKen
dc.contributor.institutionEvolutionary Adaptive Genomics, Institute for Biochemistry and Biology, Department of Mathematics and Natural Sciences, University of Potsdam, Karl-Liebknechtstraße 24-25, Potsdam, 14476, Germanyen
kaust.authorEriksson, Andersen
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