Tin-free visible light photoredox catalysed cyclisation of enamides as a mild procedure for the synthesis of γ-lactams

Handle URI:
http://hdl.handle.net/10754/617240
Title:
Tin-free visible light photoredox catalysed cyclisation of enamides as a mild procedure for the synthesis of γ-lactams
Authors:
Fava, Eleonora; Nakajima, Masaki; Tabak, Martin B.; Rueping, Magnus ( 0000-0003-4580-5227 )
Abstract:
The first visible light mediated tin-free cyclisation of α-chloroenamides leading to the synthesis of substituted γ-lactams with excellent stereoselectivity is reported. The protocol employs the single-electron reduction of activated C–Cl bonds, which are typically inert towards reduction.
KAUST Department:
KAUST Catalysis Center (KCC)
Citation:
Tin-free visible light photoredox catalysed cyclisation of enamides as a mild procedure for the synthesis of γ-lactams 2016 Green Chem.
Publisher:
Royal Society of Chemistry (RSC)
Journal:
Green Chem.
Issue Date:
13-Jul-2016
DOI:
10.1039/C6GC01099G
Type:
Article
ISSN:
1463-9262; 1463-9270
Sponsors:
The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013)/ERC Grant Agreement No. 617044 (SunCatChem). Financial support by KAUST is gratefully acknowledged.
Additional Links:
http://xlink.rsc.org/?DOI=C6GC01099G
Appears in Collections:
Articles

Full metadata record

DC FieldValue Language
dc.contributor.authorFava, Eleonoraen
dc.contributor.authorNakajima, Masakien
dc.contributor.authorTabak, Martin B.en
dc.contributor.authorRueping, Magnusen
dc.date.accessioned2016-07-19T10:02:11Z-
dc.date.available2016-07-19T10:02:11Z-
dc.date.issued2016-07-13-
dc.identifier.citationTin-free visible light photoredox catalysed cyclisation of enamides as a mild procedure for the synthesis of γ-lactams 2016 Green Chem.en
dc.identifier.issn1463-9262-
dc.identifier.issn1463-9270-
dc.identifier.doi10.1039/C6GC01099G-
dc.identifier.urihttp://hdl.handle.net/10754/617240-
dc.description.abstractThe first visible light mediated tin-free cyclisation of α-chloroenamides leading to the synthesis of substituted γ-lactams with excellent stereoselectivity is reported. The protocol employs the single-electron reduction of activated C–Cl bonds, which are typically inert towards reduction.en
dc.description.sponsorshipThe research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013)/ERC Grant Agreement No. 617044 (SunCatChem). Financial support by KAUST is gratefully acknowledged.en
dc.language.isoenen
dc.publisherRoyal Society of Chemistry (RSC)en
dc.relation.urlhttp://xlink.rsc.org/?DOI=C6GC01099Gen
dc.rightsThis article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. http://creativecommons.org/licenses/by-nc/3.0/en
dc.titleTin-free visible light photoredox catalysed cyclisation of enamides as a mild procedure for the synthesis of γ-lactamsen
dc.typeArticleen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.identifier.journalGreen Chem.en
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionInstitute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, Aachen, Germanyen
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)en
kaust.authorFava, Eleonoraen
kaust.authorRueping, Magnusen
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