Metabolic pathway redundancy within the apicomplexan-dinoflagellate radiation argues against an ancient chromalveolate plastid

Handle URI:
http://hdl.handle.net/10754/605635
Title:
Metabolic pathway redundancy within the apicomplexan-dinoflagellate radiation argues against an ancient chromalveolate plastid
Authors:
Waller, Ross F.; Gornik, Sebastian G.; Koreny, Ludek; Pain, Arnab ( 0000-0002-1755-2819 )
Abstract:
The chromalveolate hypothesis presents an attractively simple explanation for the presence of red algal-derived secondary plastids in 5 major eukaryotic lineages: “chromista” phyla, cryptophytes, haptophytes and ochrophytes; and alveolate phyla, dinoflagellates and apicomplexans. It posits that a single secondary endosymbiotic event occurred in a common ancestor of these diverse groups, and that this ancient plastid has since been maintained by vertical inheritance only. Substantial testing of this hypothesis by molecular phylogenies has, however, consistently failed to provide support for the predicted monophyly of the host organisms that harbour these plastids—the “chromalveolates.” This lack of support does not disprove the chromalveolate hypothesis per se, but rather drives the proposed endosymbiosis deeper into the eukaryotic tree, and requires multiple plastid losses to have occurred within intervening aplastidic lineages. An alternative perspective on plastid evolution is offered by considering the metabolic partnership between the endosymbiont and its host cell. A recent analysis of metabolic pathways in a deep-branching dinoflagellate indicates a high level of pathway redundancy in the common ancestor of apicomplexans and dinoflagellates, and differential losses of these pathways soon after radiation of the major extant lineages. This suggests that vertical inheritance of an ancient plastid in alveolates is highly unlikely as it would necessitate maintenance of redundant pathways over very long evolutionary timescales.
KAUST Department:
Pathogen Genomics Laboratory; Biological and Environmental Sciences and Engineering (BESE) Division
Citation:
Metabolic pathway redundancy within the apicomplexan-dinoflagellate radiation argues against an ancient chromalveolate plastid 2015, 9 (1):e1116653 Communicative & Integrative Biology
Publisher:
Informa UK Limited
Journal:
Communicative & Integrative Biology
Issue Date:
8-Dec-2015
DOI:
10.1080/19420889.2015.1116653
Type:
Article
ISSN:
1942-0889
Sponsors:
This work was supported by the MRC (MR/M011690/1). SGG was supported by Science Foundation Ireland Grant 13/SIRG/ 2125.
Additional Links:
http://www.tandfonline.com/doi/full/10.1080/19420889.2015.1116653
Appears in Collections:
Articles; Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorWaller, Ross F.en
dc.contributor.authorGornik, Sebastian G.en
dc.contributor.authorKoreny, Ludeken
dc.contributor.authorPain, Arnaben
dc.date.accessioned2016-04-17T09:19:51Zen
dc.date.available2016-04-17T09:19:51Zen
dc.date.issued2015-12-08en
dc.identifier.citationMetabolic pathway redundancy within the apicomplexan-dinoflagellate radiation argues against an ancient chromalveolate plastid 2015, 9 (1):e1116653 Communicative & Integrative Biologyen
dc.identifier.issn1942-0889en
dc.identifier.doi10.1080/19420889.2015.1116653en
dc.identifier.urihttp://hdl.handle.net/10754/605635en
dc.description.abstractThe chromalveolate hypothesis presents an attractively simple explanation for the presence of red algal-derived secondary plastids in 5 major eukaryotic lineages: “chromista” phyla, cryptophytes, haptophytes and ochrophytes; and alveolate phyla, dinoflagellates and apicomplexans. It posits that a single secondary endosymbiotic event occurred in a common ancestor of these diverse groups, and that this ancient plastid has since been maintained by vertical inheritance only. Substantial testing of this hypothesis by molecular phylogenies has, however, consistently failed to provide support for the predicted monophyly of the host organisms that harbour these plastids—the “chromalveolates.” This lack of support does not disprove the chromalveolate hypothesis per se, but rather drives the proposed endosymbiosis deeper into the eukaryotic tree, and requires multiple plastid losses to have occurred within intervening aplastidic lineages. An alternative perspective on plastid evolution is offered by considering the metabolic partnership between the endosymbiont and its host cell. A recent analysis of metabolic pathways in a deep-branching dinoflagellate indicates a high level of pathway redundancy in the common ancestor of apicomplexans and dinoflagellates, and differential losses of these pathways soon after radiation of the major extant lineages. This suggests that vertical inheritance of an ancient plastid in alveolates is highly unlikely as it would necessitate maintenance of redundant pathways over very long evolutionary timescales.en
dc.description.sponsorshipThis work was supported by the MRC (MR/M011690/1). SGG was supported by Science Foundation Ireland Grant 13/SIRG/ 2125.en
dc.language.isoenen
dc.publisherInforma UK Limiteden
dc.relation.urlhttp://www.tandfonline.com/doi/full/10.1080/19420889.2015.1116653en
dc.rightsPublished with license by Taylor & Francis Group, LLC© Ross F. Waller, Sebastian G. Gornik, Ludek Koreny, and Arnab Pain. This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. Permission is granted subject to the terms of the License under which the work was published. Please check the License conditions for the work which you wish to reuse. Full and appropriate attribution must be given. This permission does not cover any third party copyrighted material which may appear in the work requested.en
dc.subjectapicomplexaen
dc.subjectchromalveolateen
dc.subjectdinoflagellatesen
dc.subjectendosymbiosisen
dc.subjectplastiden
dc.titleMetabolic pathway redundancy within the apicomplexan-dinoflagellate radiation argues against an ancient chromalveolate plastiden
dc.typeArticleen
dc.contributor.departmentPathogen Genomics Laboratoryen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.identifier.journalCommunicative & Integrative Biologyen
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionDepartment of Biochemistry, University of Cambridge, Cambridge, UKen
dc.contributor.institutionSchool of Natural Sciences, National University of Ireland Galway, Galway, Irelanden
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)en
kaust.authorPain, Arnaben
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