Controllable Microdroplet Splitting via Additional Lateral Flow and its Application in Rapid Synthesis of Multi-scale Microspheres

Handle URI:
http://hdl.handle.net/10754/600246
Title:
Controllable Microdroplet Splitting via Additional Lateral Flow and its Application in Rapid Synthesis of Multi-scale Microspheres
Authors:
Zhou, Bingpu; Wang, Cong; Xiao, Xiao; Hui, Yu Sanna; Cao, Yulin; Wen, Weijia
Abstract:
In this paper, we demonstrate that controllable microdroplet splitting could be obtained via additional lateral flow with simplicity and high controllability. The volume ratio of the two splitting products can be flexibly regulated by adjusting the flow rate ratio between the main and additional lateral flows. The splitting phenomena under different main flow rates were investigated. A volume ratio up to 200 : 1 of the two daughter droplets under a relatively higher main flow rate was experimentally achieved based on our approach. In this case, we have successfully achieved uniform daughter droplets with a smallest diameter of ∼19.5 ± 1.6 μm. With such a design, we have synthesized uniform PEGDA hydrogel microspheres with diameters ranging from ∼30 μm to over hundred of micrometers simultaneously.
Citation:
Zhou B, Wang C, Xiao X, Hui YS, Cao Y, et al. (2015) Controllable Microdroplet Splitting via Additional Lateral Flow and its Application in Rapid Synthesis of Multi-scale Microspheres. RSC Adv. Available: http://dx.doi.org/10.1039/c4ra15552a.
Publisher:
Royal Society of Chemistry (RSC)
Journal:
RSC Adv.
Issue Date:
2015
DOI:
10.1039/c4ra15552a
Type:
Article
ISSN:
2046-2069
Sponsors:
The authors would like to acknowledge the support by Hong Kong RGC grant HKUST 605411 and NSFC/RGC joint grant N_HKUST601/11. The work was also partially supported by the Nanoscience and Nanotechnology Program at HKUST.
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Full metadata record

DC FieldValue Language
dc.contributor.authorZhou, Bingpuen
dc.contributor.authorWang, Congen
dc.contributor.authorXiao, Xiaoen
dc.contributor.authorHui, Yu Sannaen
dc.contributor.authorCao, Yulinen
dc.contributor.authorWen, Weijiaen
dc.date.accessioned2016-02-28T07:59:55Zen
dc.date.available2016-02-28T07:59:55Zen
dc.date.issued2015en
dc.identifier.citationZhou B, Wang C, Xiao X, Hui YS, Cao Y, et al. (2015) Controllable Microdroplet Splitting via Additional Lateral Flow and its Application in Rapid Synthesis of Multi-scale Microspheres. RSC Adv. Available: http://dx.doi.org/10.1039/c4ra15552a.en
dc.identifier.issn2046-2069en
dc.identifier.doi10.1039/c4ra15552aen
dc.identifier.urihttp://hdl.handle.net/10754/600246en
dc.description.abstractIn this paper, we demonstrate that controllable microdroplet splitting could be obtained via additional lateral flow with simplicity and high controllability. The volume ratio of the two splitting products can be flexibly regulated by adjusting the flow rate ratio between the main and additional lateral flows. The splitting phenomena under different main flow rates were investigated. A volume ratio up to 200 : 1 of the two daughter droplets under a relatively higher main flow rate was experimentally achieved based on our approach. In this case, we have successfully achieved uniform daughter droplets with a smallest diameter of ∼19.5 ± 1.6 μm. With such a design, we have synthesized uniform PEGDA hydrogel microspheres with diameters ranging from ∼30 μm to over hundred of micrometers simultaneously.en
dc.description.sponsorshipThe authors would like to acknowledge the support by Hong Kong RGC grant HKUST 605411 and NSFC/RGC joint grant N_HKUST601/11. The work was also partially supported by the Nanoscience and Nanotechnology Program at HKUST.en
dc.publisherRoyal Society of Chemistry (RSC)en
dc.titleControllable Microdroplet Splitting via Additional Lateral Flow and its Application in Rapid Synthesis of Multi-scale Microspheresen
dc.typeArticleen
dc.identifier.journalRSC Adv.en
dc.contributor.institutionNano Science and Technology Program, Hong Kong University of Science and Technology, Clear Water BayKowloon, Hong Kongen
kaust.authorXiao, Xiaoen
kaust.authorCao, Yulinen
kaust.authorWen, Weijiaen
kaust.grant.fundedcenterKAUST-HKUST Micro/Nanofluidic Joint Laboratoryen
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