Continuous particle focusing in a waved microchannel using negative dc dielectrophoresis

Handle URI:
http://hdl.handle.net/10754/600245
Title:
Continuous particle focusing in a waved microchannel using negative dc dielectrophoresis
Authors:
Li, Ming; Li, Shunbo; Cao, Wenbin; Li, Weihua; Wen, Weijia; Alici, Gursel
Abstract:
We present a waved microchannel for continuous focusing of microparticles and cells using negative direct current (dc) dielectrophoresis. The waved channel is composed of consecutive s-shaped curved channels in series to generate an electric field gradient required for the dielectrophoretic effect. When particles move electrokinetically through the channel, the experienced negative dielectrophoretic forces alternate directions within two adjacent semicircular microchannels, leading to a focused continuous-flow stream along the channel centerline. Both the experimentally observed and numerically simulated results of the focusing performance are reported, which coincide acceptably in proportion to the specified dimensions (i.e. inlet and outlet of the waved channel). How the applied electric field, particle size and medium concentration affect the performance was studied by focusing polystyrene microparticles of varying sizes. As an application in the field of biology, the focusing of yeast cells in the waved mcirochannel was tested. This waved microchannel shows a great potential for microflow cytometry applications and is expected to be widely used before different processing steps in lab-on-A-chip devices with integrated functions. © 2012 IOP Publishing Ltd.
Citation:
Li M, Li S, Cao W, Li W, Wen W, et al. (2012) Continuous particle focusing in a waved microchannel using negative dc dielectrophoresis. Journal of Micromechanics and Microengineering 22: 095001. Available: http://dx.doi.org/10.1088/0960-1317/22/9/095001.
Publisher:
IOP Publishing
Journal:
Journal of Micromechanics and Microengineering
Issue Date:
26-Jul-2012
DOI:
10.1088/0960-1317/22/9/095001
Type:
Article
ISSN:
0960-1317; 1361-6439
Sponsors:
The authors wish to thank the University of Wollongong funding support to promote the collaboration with The Hong Kong University of Science and Technology through an international linkage scheme.
Appears in Collections:
Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorLi, Mingen
dc.contributor.authorLi, Shunboen
dc.contributor.authorCao, Wenbinen
dc.contributor.authorLi, Weihuaen
dc.contributor.authorWen, Weijiaen
dc.contributor.authorAlici, Gurselen
dc.date.accessioned2016-02-28T07:59:54Zen
dc.date.available2016-02-28T07:59:54Zen
dc.date.issued2012-07-26en
dc.identifier.citationLi M, Li S, Cao W, Li W, Wen W, et al. (2012) Continuous particle focusing in a waved microchannel using negative dc dielectrophoresis. Journal of Micromechanics and Microengineering 22: 095001. Available: http://dx.doi.org/10.1088/0960-1317/22/9/095001.en
dc.identifier.issn0960-1317en
dc.identifier.issn1361-6439en
dc.identifier.doi10.1088/0960-1317/22/9/095001en
dc.identifier.urihttp://hdl.handle.net/10754/600245en
dc.description.abstractWe present a waved microchannel for continuous focusing of microparticles and cells using negative direct current (dc) dielectrophoresis. The waved channel is composed of consecutive s-shaped curved channels in series to generate an electric field gradient required for the dielectrophoretic effect. When particles move electrokinetically through the channel, the experienced negative dielectrophoretic forces alternate directions within two adjacent semicircular microchannels, leading to a focused continuous-flow stream along the channel centerline. Both the experimentally observed and numerically simulated results of the focusing performance are reported, which coincide acceptably in proportion to the specified dimensions (i.e. inlet and outlet of the waved channel). How the applied electric field, particle size and medium concentration affect the performance was studied by focusing polystyrene microparticles of varying sizes. As an application in the field of biology, the focusing of yeast cells in the waved mcirochannel was tested. This waved microchannel shows a great potential for microflow cytometry applications and is expected to be widely used before different processing steps in lab-on-A-chip devices with integrated functions. © 2012 IOP Publishing Ltd.en
dc.description.sponsorshipThe authors wish to thank the University of Wollongong funding support to promote the collaboration with The Hong Kong University of Science and Technology through an international linkage scheme.en
dc.publisherIOP Publishingen
dc.titleContinuous particle focusing in a waved microchannel using negative dc dielectrophoresisen
dc.typeArticleen
dc.identifier.journalJournal of Micromechanics and Microengineeringen
dc.contributor.institutionSchool of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, Wollongong, NSW 2522, Australiaen
dc.contributor.institutionDepartment of Physics, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kongen
kaust.authorCao, Wenbinen
kaust.authorWen, Weijiaen
kaust.grant.fundedcenterKAUST-HKUST Micro/Nanofluidic Joint Laboratoryen
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