Handle URI:
http://hdl.handle.net/10754/600195
Title:
Wildlife disease elimination and density dependence
Authors:
Potapov, A.; Merrill, E.; Lewis, M. A.
Abstract:
Disease control by managers is a crucial response to emerging wildlife epidemics, yet the means of control may be limited by the method of disease transmission. In particular, it is widely held that population reduction, while effective for controlling diseases that are subject to density-dependent (DD) transmission, is ineffective for controlling diseases that are subject to frequency-dependent (FD) transmission. We investigate control for horizontally transmitted diseases with FD transmission where the control is via culling or harvest that is non-selective with respect to infection and the population can compensate through DD recruitment or survival. Using a mathematical model, we show that culling or harvesting can eradicate the disease, even when transmission dynamics are FD. Eradication can be achieved under FD transmission when DD birth or recruitment induces compensatory growth of new, healthy individuals, which has the net effect of reducing disease prevalence by dilution. We also show that if harvest is used simultaneously with vaccination, and there is high enough transmission coefficient, application of both controls may be less efficient than vaccination alone. We illustrate the effects of these control approaches on disease prevalence for chronic wasting disease in deer where the disease is transmitted directly among deer and through the environment.
Citation:
Potapov A, Merrill E, Lewis MA (2012) Wildlife disease elimination and density dependence. Proceedings of the Royal Society B: Biological Sciences 279: 3139–3145. Available: http://dx.doi.org/10.1098/rspb.2012.0520.
Publisher:
The Royal Society
Journal:
Proceedings of the Royal Society B: Biological Sciences
KAUST Grant Number:
KUK-CI013-04
Issue Date:
16-May-2012
DOI:
10.1098/rspb.2012.0520
PubMed ID:
22593103
PubMed Central ID:
PMC3385729
Type:
Article
ISSN:
0962-8452; 1471-2954
Sponsors:
This work has been supported by Alberta Prion Research Institute and Alberta Innovation through grants (E. Merrill: RES0004230), Natural Sciences and Engineering Research Council of Canada Discovery Grants (E. M., M. A. L.) Canada Research Chair (M. A. L.), NSERC Accelerator Grant (M. A. L.) and Research Fellowship from Oxford Centre for Collaborative and Applied Mathematics supported by Award no. KUK-CI013-04 made by King Abdullah University of Science and Technology (KAUST) (M. A. L.). We thank reviewers for helpful suggestions.
Appears in Collections:
Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorPotapov, A.en
dc.contributor.authorMerrill, E.en
dc.contributor.authorLewis, M. A.en
dc.date.accessioned2016-02-28T06:44:57Zen
dc.date.available2016-02-28T06:44:57Zen
dc.date.issued2012-05-16en
dc.identifier.citationPotapov A, Merrill E, Lewis MA (2012) Wildlife disease elimination and density dependence. Proceedings of the Royal Society B: Biological Sciences 279: 3139–3145. Available: http://dx.doi.org/10.1098/rspb.2012.0520.en
dc.identifier.issn0962-8452en
dc.identifier.issn1471-2954en
dc.identifier.pmid22593103en
dc.identifier.doi10.1098/rspb.2012.0520en
dc.identifier.urihttp://hdl.handle.net/10754/600195en
dc.description.abstractDisease control by managers is a crucial response to emerging wildlife epidemics, yet the means of control may be limited by the method of disease transmission. In particular, it is widely held that population reduction, while effective for controlling diseases that are subject to density-dependent (DD) transmission, is ineffective for controlling diseases that are subject to frequency-dependent (FD) transmission. We investigate control for horizontally transmitted diseases with FD transmission where the control is via culling or harvest that is non-selective with respect to infection and the population can compensate through DD recruitment or survival. Using a mathematical model, we show that culling or harvesting can eradicate the disease, even when transmission dynamics are FD. Eradication can be achieved under FD transmission when DD birth or recruitment induces compensatory growth of new, healthy individuals, which has the net effect of reducing disease prevalence by dilution. We also show that if harvest is used simultaneously with vaccination, and there is high enough transmission coefficient, application of both controls may be less efficient than vaccination alone. We illustrate the effects of these control approaches on disease prevalence for chronic wasting disease in deer where the disease is transmitted directly among deer and through the environment.en
dc.description.sponsorshipThis work has been supported by Alberta Prion Research Institute and Alberta Innovation through grants (E. Merrill: RES0004230), Natural Sciences and Engineering Research Council of Canada Discovery Grants (E. M., M. A. L.) Canada Research Chair (M. A. L.), NSERC Accelerator Grant (M. A. L.) and Research Fellowship from Oxford Centre for Collaborative and Applied Mathematics supported by Award no. KUK-CI013-04 made by King Abdullah University of Science and Technology (KAUST) (M. A. L.). We thank reviewers for helpful suggestions.en
dc.publisherThe Royal Societyen
dc.subjectChronic wasting diseaseen
dc.subjectDisease managementen
dc.subjectDisease modellingen
dc.subjectFrequency-dependent transmissionen
dc.subject.meshAnimals, Wilden
dc.subject.meshDeeren
dc.titleWildlife disease elimination and density dependenceen
dc.typeArticleen
dc.identifier.journalProceedings of the Royal Society B: Biological Sciencesen
dc.identifier.pmcidPMC3385729en
dc.contributor.institutionUniversity of Alberta, Edmonton, Canadaen
kaust.grant.numberKUK-CI013-04en

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