Well-Defined Copper(I) Fluoroalkoxide Complexes for Trifluoroethoxylation of Aryl and Heteroaryl Bromides

Handle URI:
http://hdl.handle.net/10754/600190
Title:
Well-Defined Copper(I) Fluoroalkoxide Complexes for Trifluoroethoxylation of Aryl and Heteroaryl Bromides
Authors:
Huang, Ronglu; Huang, Yangjie; Lin, Xiaoxi; Rong, Mingguang; Weng, Zhiqiang
Abstract:
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Copper(I) fluoroalkoxide complexes bearing dinitrogen ligands were synthesized and the structure and reactivity of the complexes toward trifluoroethoxylation, pentafluoropropoxylation, and tetrafluoropropoxylation of aryl and heteroaryl bromides were investigated. Efficiency drive: A series of copper(I) fluoroalkoxide complexes bearing N,N ligands have been prepared and structurally characterized. These well-defined complexes serve as efficient reagents for the fluoroalkoxylation of aryl and heteroaryl bromides to produce a wide range of trifluoroethyl, pentafluoropropyl, and tetrafluoropropyl (hetero)aryl ethers in good to excellent yields.
Citation:
Huang R, Huang Y, Lin X, Rong M, Weng Z (2015) Well-Defined Copper(I) Fluoroalkoxide Complexes for Trifluoroethoxylation of Aryl and Heteroaryl Bromides. Angew Chem Int Ed 54: 5736–5739. Available: http://dx.doi.org/10.1002/anie.201501257.
Publisher:
Wiley-Blackwell
Journal:
Angewandte Chemie International Edition
Issue Date:
17-Mar-2015
DOI:
10.1002/anie.201501257
PubMed ID:
25783796
Type:
Article
ISSN:
1433-7851
Sponsors:
Financial support from the National Natural Science Foundation of China (NSFC) (grant number 21372044), the Research Fund for the Doctoral Program of Higher Education of China (grant number 20123514110003), and Fuzhou University (grant numbers 022318, 022494) is gratefully acknowledged. We thank Prof. Kuo-Wei Huang (KAUST) for insightful discussions.
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Full metadata record

DC FieldValue Language
dc.contributor.authorHuang, Rongluen
dc.contributor.authorHuang, Yangjieen
dc.contributor.authorLin, Xiaoxien
dc.contributor.authorRong, Mingguangen
dc.contributor.authorWeng, Zhiqiangen
dc.date.accessioned2016-02-28T06:44:48Zen
dc.date.available2016-02-28T06:44:48Zen
dc.date.issued2015-03-17en
dc.identifier.citationHuang R, Huang Y, Lin X, Rong M, Weng Z (2015) Well-Defined Copper(I) Fluoroalkoxide Complexes for Trifluoroethoxylation of Aryl and Heteroaryl Bromides. Angew Chem Int Ed 54: 5736–5739. Available: http://dx.doi.org/10.1002/anie.201501257.en
dc.identifier.issn1433-7851en
dc.identifier.pmid25783796en
dc.identifier.doi10.1002/anie.201501257en
dc.identifier.urihttp://hdl.handle.net/10754/600190en
dc.description.abstract© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Copper(I) fluoroalkoxide complexes bearing dinitrogen ligands were synthesized and the structure and reactivity of the complexes toward trifluoroethoxylation, pentafluoropropoxylation, and tetrafluoropropoxylation of aryl and heteroaryl bromides were investigated. Efficiency drive: A series of copper(I) fluoroalkoxide complexes bearing N,N ligands have been prepared and structurally characterized. These well-defined complexes serve as efficient reagents for the fluoroalkoxylation of aryl and heteroaryl bromides to produce a wide range of trifluoroethyl, pentafluoropropyl, and tetrafluoropropyl (hetero)aryl ethers in good to excellent yields.en
dc.description.sponsorshipFinancial support from the National Natural Science Foundation of China (NSFC) (grant number 21372044), the Research Fund for the Doctoral Program of Higher Education of China (grant number 20123514110003), and Fuzhou University (grant numbers 022318, 022494) is gratefully acknowledged. We thank Prof. Kuo-Wei Huang (KAUST) for insightful discussions.en
dc.publisherWiley-Blackwellen
dc.subjectC-O bondsen
dc.subjectcopperen
dc.subjectcross-couplingen
dc.subjecttrifluoroethoxylationen
dc.titleWell-Defined Copper(I) Fluoroalkoxide Complexes for Trifluoroethoxylation of Aryl and Heteroaryl Bromidesen
dc.typeArticleen
dc.identifier.journalAngewandte Chemie International Editionen
dc.contributor.institutionFuzhou University, Fuzhou, Chinaen
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