Transcription factor PIF4 controls the thermosensory activation of flowering

Handle URI:
http://hdl.handle.net/10754/600055
Title:
Transcription factor PIF4 controls the thermosensory activation of flowering
Authors:
Kumar, S. Vinod; Lucyshyn, Doris; Jaeger, Katja E.; Alós, Enriqueta; Alvey, Elizabeth; Harberd, Nicholas P.; Wigge, Philip A.
Abstract:
Plant growth and development are strongly affected by small differences in temperature. Current climate change has already altered global plant phenology and distribution, and projected increases in temperature pose a significant challenge to agriculture. Despite the important role of temperature on plant development, the underlying pathways are unknown. It has previously been shown that thermal acceleration of flowering is dependent on the florigen, FLOWERING LOCUS T (FT). How this occurs is, however, not understood, because the major pathway known to upregulate FT, the photoperiod pathway, is not required for thermal acceleration of flowering. Here we demonstrate a direct mechanism by which increasing temperature causes the bHLH transcription factor PHYTOCHROME INTERACTING FACTOR4 (PIF4) to activate FT. Our findings provide a new understanding of how plants control their timing of reproduction in response to temperature. Flowering time is an important trait in crops as well as affecting the life cycles of pollinator species. A molecular understanding of how temperature affects flowering will be important for mitigating the effects of climate change. © 2012 Macmillan Publishers Limited. All rights reserved.
Citation:
Kumar SV, Lucyshyn D, Jaeger KE, Alós E, Alvey E, et al. (2012) Transcription factor PIF4 controls the thermosensory activation of flowering. Nature 484: 242–245. Available: http://dx.doi.org/10.1038/nature10928.
Publisher:
Springer Nature
Journal:
Nature
KAUST Grant Number:
KUK-I1-002-03
Issue Date:
21-Mar-2012
DOI:
10.1038/nature10928
PubMed ID:
22437497
Type:
Article
ISSN:
0028-0836; 1476-4687
Sponsors:
We thank S. Prat, C. Fankhauser, K. Franklin, K. Goto, G. Coupland and D. Weigel for seeds. We are grateful to members of the Wigge laboratory for discussions. This work was supported in part by award No. KUK-I1-002-03 (to N.P.H.) made by King Abdullah University of Science and Technology and a Biotechnology and Biological Sciences Research Council (BBSRC) grant BB/I019022/1 (to S.V.K.). D.L. was supported by an Erwin Schroedinger Fellowship from the Austrian Science Fund FWF. P.A.W. was supported by start-up funds from the John Innes Centre and BBSRC, a BBSRC grant (BB/D0100470/1) and a European Research Council Starting Grant (ERC 243140).
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Full metadata record

DC FieldValue Language
dc.contributor.authorKumar, S. Vinoden
dc.contributor.authorLucyshyn, Dorisen
dc.contributor.authorJaeger, Katja E.en
dc.contributor.authorAlós, Enriquetaen
dc.contributor.authorAlvey, Elizabethen
dc.contributor.authorHarberd, Nicholas P.en
dc.contributor.authorWigge, Philip A.en
dc.date.accessioned2016-02-28T06:35:10Zen
dc.date.available2016-02-28T06:35:10Zen
dc.date.issued2012-03-21en
dc.identifier.citationKumar SV, Lucyshyn D, Jaeger KE, Alós E, Alvey E, et al. (2012) Transcription factor PIF4 controls the thermosensory activation of flowering. Nature 484: 242–245. Available: http://dx.doi.org/10.1038/nature10928.en
dc.identifier.issn0028-0836en
dc.identifier.issn1476-4687en
dc.identifier.pmid22437497en
dc.identifier.doi10.1038/nature10928en
dc.identifier.urihttp://hdl.handle.net/10754/600055en
dc.description.abstractPlant growth and development are strongly affected by small differences in temperature. Current climate change has already altered global plant phenology and distribution, and projected increases in temperature pose a significant challenge to agriculture. Despite the important role of temperature on plant development, the underlying pathways are unknown. It has previously been shown that thermal acceleration of flowering is dependent on the florigen, FLOWERING LOCUS T (FT). How this occurs is, however, not understood, because the major pathway known to upregulate FT, the photoperiod pathway, is not required for thermal acceleration of flowering. Here we demonstrate a direct mechanism by which increasing temperature causes the bHLH transcription factor PHYTOCHROME INTERACTING FACTOR4 (PIF4) to activate FT. Our findings provide a new understanding of how plants control their timing of reproduction in response to temperature. Flowering time is an important trait in crops as well as affecting the life cycles of pollinator species. A molecular understanding of how temperature affects flowering will be important for mitigating the effects of climate change. © 2012 Macmillan Publishers Limited. All rights reserved.en
dc.description.sponsorshipWe thank S. Prat, C. Fankhauser, K. Franklin, K. Goto, G. Coupland and D. Weigel for seeds. We are grateful to members of the Wigge laboratory for discussions. This work was supported in part by award No. KUK-I1-002-03 (to N.P.H.) made by King Abdullah University of Science and Technology and a Biotechnology and Biological Sciences Research Council (BBSRC) grant BB/I019022/1 (to S.V.K.). D.L. was supported by an Erwin Schroedinger Fellowship from the Austrian Science Fund FWF. P.A.W. was supported by start-up funds from the John Innes Centre and BBSRC, a BBSRC grant (BB/D0100470/1) and a European Research Council Starting Grant (ERC 243140).en
dc.publisherSpringer Natureen
dc.titleTranscription factor PIF4 controls the thermosensory activation of floweringen
dc.typeArticleen
dc.identifier.journalNatureen
dc.contributor.institutionJohn Innes Centre, Norwich, United Kingdomen
dc.contributor.institutionUniversity of Oxford, Oxford, United Kingdomen
dc.contributor.institutionBOKU - University of Natural Resources and Life Sciences, Vienna, Austriaen
dc.contributor.institutionUniversity of Cambridge, Cambridge, United Kingdomen
kaust.grant.numberKUK-I1-002-03en
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