Prodigious Effects of Concentration Intensification on Nanoparticle Synthesis: A High-Quality, Scalable Approach

Handle URI:
http://hdl.handle.net/10754/599409
Title:
Prodigious Effects of Concentration Intensification on Nanoparticle Synthesis: A High-Quality, Scalable Approach
Authors:
Williamson, Curtis B.; Nevers, Douglas R.; Hanrath, Tobias; Robinson, Richard D.
Abstract:
© 2015 American Chemical Society. Realizing the promise of nanoparticle-based technologies demands more efficient, robust synthesis methods (i.e., process intensification) that consistently produce large quantities of high-quality nanoparticles (NPs). We explored NP synthesis via the heat-up method in a regime of previously unexplored high concentrations near the solubility limit of the precursors. We discovered that in this highly concentrated and viscous regime the NP synthesis parameters are less sensitive to experimental variability and thereby provide a robust, scalable, and size-focusing NP synthesis. Specifically, we synthesize high-quality metal sulfide NPs (<7% relative standard deviation for Cu2-xS and CdS), and demonstrate a 10-1000-fold increase in Cu2-xS NP production (>200 g) relative to the current field of large-scale (0.1-5 g yields) and laboratory-scale (<0.1 g) efforts. Compared to conventional synthesis methods (hot injection with dilute precursor concentration) characterized by rapid growth and low yield, our highly concentrated NP system supplies remarkably controlled growth rates and a 10-fold increase in NP volumetric production capacity (86 g/L). The controlled growth, high yield, and robust nature of highly concentrated solutions can facilitate large-scale nanomanufacturing of NPs by relaxing the synthesis requirements to achieve monodisperse products. Mechanistically, our investigation of the thermal and rheological properties and growth rates reveals that this high concentration regime has reduced mass diffusion (a 5-fold increase in solution viscosity), is stable to thermal perturbations (64% increase in heat capacity), and is resistant to Ostwald ripening.
Citation:
Williamson CB, Nevers DR, Hanrath T, Robinson RD (2015) Prodigious Effects of Concentration Intensification on Nanoparticle Synthesis: A High-Quality, Scalable Approach. Journal of the American Chemical Society 137: 15843–15851. Available: http://dx.doi.org/10.1021/jacs.5b10006.
Publisher:
American Chemical Society (ACS)
Journal:
Journal of the American Chemical Society
KAUST Grant Number:
KUS-C1-018-02
Issue Date:
23-Dec-2015
DOI:
10.1021/jacs.5b10006
PubMed ID:
26592380
Type:
Article
ISSN:
0002-7863; 1520-5126
Sponsors:
This work was supported in part by the National Science Foundation under award number (CMMI – 1344562). This work also made use of the Cornell Center for Materials Research Shared Facilities, which are supported through the NSF MRSEC program (DMR-1120296), and KAUST-CU prototyping lab, supported by King Abdullah University of Science and Technology (KAUST) (Award No. KUS-C1-018-02).
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Full metadata record

DC FieldValue Language
dc.contributor.authorWilliamson, Curtis B.en
dc.contributor.authorNevers, Douglas R.en
dc.contributor.authorHanrath, Tobiasen
dc.contributor.authorRobinson, Richard D.en
dc.date.accessioned2016-02-28T05:50:36Zen
dc.date.available2016-02-28T05:50:36Zen
dc.date.issued2015-12-23en
dc.identifier.citationWilliamson CB, Nevers DR, Hanrath T, Robinson RD (2015) Prodigious Effects of Concentration Intensification on Nanoparticle Synthesis: A High-Quality, Scalable Approach. Journal of the American Chemical Society 137: 15843–15851. Available: http://dx.doi.org/10.1021/jacs.5b10006.en
dc.identifier.issn0002-7863en
dc.identifier.issn1520-5126en
dc.identifier.pmid26592380en
dc.identifier.doi10.1021/jacs.5b10006en
dc.identifier.urihttp://hdl.handle.net/10754/599409en
dc.description.abstract© 2015 American Chemical Society. Realizing the promise of nanoparticle-based technologies demands more efficient, robust synthesis methods (i.e., process intensification) that consistently produce large quantities of high-quality nanoparticles (NPs). We explored NP synthesis via the heat-up method in a regime of previously unexplored high concentrations near the solubility limit of the precursors. We discovered that in this highly concentrated and viscous regime the NP synthesis parameters are less sensitive to experimental variability and thereby provide a robust, scalable, and size-focusing NP synthesis. Specifically, we synthesize high-quality metal sulfide NPs (<7% relative standard deviation for Cu2-xS and CdS), and demonstrate a 10-1000-fold increase in Cu2-xS NP production (>200 g) relative to the current field of large-scale (0.1-5 g yields) and laboratory-scale (<0.1 g) efforts. Compared to conventional synthesis methods (hot injection with dilute precursor concentration) characterized by rapid growth and low yield, our highly concentrated NP system supplies remarkably controlled growth rates and a 10-fold increase in NP volumetric production capacity (86 g/L). The controlled growth, high yield, and robust nature of highly concentrated solutions can facilitate large-scale nanomanufacturing of NPs by relaxing the synthesis requirements to achieve monodisperse products. Mechanistically, our investigation of the thermal and rheological properties and growth rates reveals that this high concentration regime has reduced mass diffusion (a 5-fold increase in solution viscosity), is stable to thermal perturbations (64% increase in heat capacity), and is resistant to Ostwald ripening.en
dc.description.sponsorshipThis work was supported in part by the National Science Foundation under award number (CMMI – 1344562). This work also made use of the Cornell Center for Materials Research Shared Facilities, which are supported through the NSF MRSEC program (DMR-1120296), and KAUST-CU prototyping lab, supported by King Abdullah University of Science and Technology (KAUST) (Award No. KUS-C1-018-02).en
dc.publisherAmerican Chemical Society (ACS)en
dc.titleProdigious Effects of Concentration Intensification on Nanoparticle Synthesis: A High-Quality, Scalable Approachen
dc.typeArticleen
dc.identifier.journalJournal of the American Chemical Societyen
dc.contributor.institutionCornell University, Ithaca, United Statesen
kaust.grant.numberKUS-C1-018-02en
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