Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics

Handle URI:
http://hdl.handle.net/10754/599121
Title:
Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics
Authors:
Barz, Matthias; Luxenhofer, Robert; Zentel, Rudolf; Vicent, María J.
Abstract:
Synthetic methods in polymer chemistry have evolved tremendously during the last decade. Nowadays more and more attention is devoted to the application of those tools in the development of the next generation of nanomedicines. Nevertheless, poly(ethylene glycol) (PEG) remains the most frequently used polymer for biomedical applications. In this review, we try to summarize recent efforts and developments in controlled polymerisation techniques that may allow alternatives to PEG based systems and can be used to improve the properties of future polymer therapeutics. © 2011 The Royal Society of Chemistry.
Citation:
Barz M, Luxenhofer R, Zentel R, Vicent MJ (2011) Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics. Polymer Chemistry 2: 1900. Available: http://dx.doi.org/10.1039/c0py00406e.
Publisher:
Royal Society of Chemistry (RSC)
Journal:
Polymer Chemistry
KAUST Grant Number:
KUK-F1-029-32
Issue Date:
2011
DOI:
10.1039/c0py00406e
Type:
Article
ISSN:
1759-9954; 1759-9962
Sponsors:
R.L. gratefully acknowledges support by the King Abdullah University of Science and Technology, KAUST (award no. KUK-F1-029-32) and ongoing support by Prof. R. Jordan. M.B. would like to thank the graduate school of excellence MAINZ, COMATT, IMPRS, the Spanish Ministry Grant (CTQ2007-606019), European Commission FP7-Health program (proposal n. 241919, LIVIMODE) and particularly the cluster of excellence SAMT of Rhineland-Palatina for support and funding.
Appears in Collections:
Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorBarz, Matthiasen
dc.contributor.authorLuxenhofer, Roberten
dc.contributor.authorZentel, Rudolfen
dc.contributor.authorVicent, María J.en
dc.date.accessioned2016-02-25T13:53:15Zen
dc.date.available2016-02-25T13:53:15Zen
dc.date.issued2011en
dc.identifier.citationBarz M, Luxenhofer R, Zentel R, Vicent MJ (2011) Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics. Polymer Chemistry 2: 1900. Available: http://dx.doi.org/10.1039/c0py00406e.en
dc.identifier.issn1759-9954en
dc.identifier.issn1759-9962en
dc.identifier.doi10.1039/c0py00406een
dc.identifier.urihttp://hdl.handle.net/10754/599121en
dc.description.abstractSynthetic methods in polymer chemistry have evolved tremendously during the last decade. Nowadays more and more attention is devoted to the application of those tools in the development of the next generation of nanomedicines. Nevertheless, poly(ethylene glycol) (PEG) remains the most frequently used polymer for biomedical applications. In this review, we try to summarize recent efforts and developments in controlled polymerisation techniques that may allow alternatives to PEG based systems and can be used to improve the properties of future polymer therapeutics. © 2011 The Royal Society of Chemistry.en
dc.description.sponsorshipR.L. gratefully acknowledges support by the King Abdullah University of Science and Technology, KAUST (award no. KUK-F1-029-32) and ongoing support by Prof. R. Jordan. M.B. would like to thank the graduate school of excellence MAINZ, COMATT, IMPRS, the Spanish Ministry Grant (CTQ2007-606019), European Commission FP7-Health program (proposal n. 241919, LIVIMODE) and particularly the cluster of excellence SAMT of Rhineland-Palatina for support and funding.en
dc.publisherRoyal Society of Chemistry (RSC)en
dc.titleOvercoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeuticsen
dc.typeArticleen
dc.identifier.journalPolymer Chemistryen
dc.contributor.institutionCentro de Investigacion Principe Felipe, Valencia, Spainen
dc.contributor.institutionJohannes Gutenberg Universitat Mainz, Mainz, Germanyen
dc.contributor.institutionTechnische Universitat Dresden, Dresden, Germanyen
kaust.grant.numberKUK-F1-029-32en
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