Osmotic actuation for microfluidic components in point-of-care applications

Handle URI:
http://hdl.handle.net/10754/599120
Title:
Osmotic actuation for microfluidic components in point-of-care applications
Authors:
Chen, Yu-Chih; Ingram, Patrick; Lou, Xia; Yoon, Euisik
Abstract:
We present a novel design of micropumps and valves driven by osmotic force for point-of-care applications. Although there have been significant progresses in microfluidic components and control devices such as fluidic diodes, switches, resonators and digital-to-analog converters, the ultimate power source still depends on bulky off-chip components, which are expensive and cannot be easily miniaturized. For point-of-care applications, it is critical to integrate all the components in a compact size at low cost. In this work, we report two key active components actuated by osmotic mechanism for total integrated microfluidic system. For the proof of concept, we have demonstrated valve actuation, which can maintain stable ON/OFF switching operations under 125 kPa back pressure. We have also implemented an osmotic pump, which can pump a high flow rate over 30 μL/min for longer than 30 minutes. The experimental data demonstrates the possibility and potential of applying osmotic actuation in point-of-care disposable microfluidics. © 2013 IEEE.
Citation:
Chen Y-C, Ingram P, Lou X, Yoon E (2013) Osmotic actuation for microfluidic components in point-of-care applications. 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS). Available: http://dx.doi.org/10.1109/MEMSYS.2013.6474448.
Publisher:
Institute of Electrical and Electronics Engineers (IEEE)
Journal:
2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS)
Issue Date:
Jan-2013
DOI:
10.1109/MEMSYS.2013.6474448
Type:
Conference Paper
Sponsors:
This work was supported in part by the Thermo Fisher Scientific Screening Technology Grant under the Center for Chemical Genomics at the Life Sciences Institute at the University of Michigan, and in part by Academic Excellence Alliance Award from KAUST.
Appears in Collections:
Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorChen, Yu-Chihen
dc.contributor.authorIngram, Patricken
dc.contributor.authorLou, Xiaen
dc.contributor.authorYoon, Euisiken
dc.date.accessioned2016-02-25T13:53:14Zen
dc.date.available2016-02-25T13:53:14Zen
dc.date.issued2013-01en
dc.identifier.citationChen Y-C, Ingram P, Lou X, Yoon E (2013) Osmotic actuation for microfluidic components in point-of-care applications. 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS). Available: http://dx.doi.org/10.1109/MEMSYS.2013.6474448.en
dc.identifier.doi10.1109/MEMSYS.2013.6474448en
dc.identifier.urihttp://hdl.handle.net/10754/599120en
dc.description.abstractWe present a novel design of micropumps and valves driven by osmotic force for point-of-care applications. Although there have been significant progresses in microfluidic components and control devices such as fluidic diodes, switches, resonators and digital-to-analog converters, the ultimate power source still depends on bulky off-chip components, which are expensive and cannot be easily miniaturized. For point-of-care applications, it is critical to integrate all the components in a compact size at low cost. In this work, we report two key active components actuated by osmotic mechanism for total integrated microfluidic system. For the proof of concept, we have demonstrated valve actuation, which can maintain stable ON/OFF switching operations under 125 kPa back pressure. We have also implemented an osmotic pump, which can pump a high flow rate over 30 μL/min for longer than 30 minutes. The experimental data demonstrates the possibility and potential of applying osmotic actuation in point-of-care disposable microfluidics. © 2013 IEEE.en
dc.description.sponsorshipThis work was supported in part by the Thermo Fisher Scientific Screening Technology Grant under the Center for Chemical Genomics at the Life Sciences Institute at the University of Michigan, and in part by Academic Excellence Alliance Award from KAUST.en
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)en
dc.titleOsmotic actuation for microfluidic components in point-of-care applicationsen
dc.typeConference Paperen
dc.identifier.journal2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS)en
dc.contributor.institutionUniversity of Michigan, Ann Arbor, United Statesen
dc.contributor.institutionUniversity Michigan Ann Arbor, Ann Arbor, United Statesen
kaust.grant.programAcademic Excellence Alliance (AEA)en
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