Interactions of a Photochromic Spiropyran with Liposome Model Membranes

Handle URI:
http://hdl.handle.net/10754/598643
Title:
Interactions of a Photochromic Spiropyran with Liposome Model Membranes
Authors:
Jonsson, Fabian; Beke-Somfai, Tamás; Andréasson, Joakim; Nordén, Bengt
Abstract:
The interactions between anionic or zwitterionic liposomes and a water-soluble, DNA-binding photochromic spiropyran are studied using UV/vis absorption and linear dichroism (LD) spectroscopy. The spectral characteristics as well as the kinetics of the thermal isomerization process in the absence and presence of the two different liposome types provide information about the environment and whether or not the spiropyran resides in the liposome membrane. By measuring LD on liposomes deformed and aligned by shear flow, further insight is obtained about interaction and binding geometry of the spiropyran at the lipid membranes. We show that the membrane interactions differ between the two types of liposomes used as well as the isomeric forms of the spiropyran photoswitch. © 2013 American Chemical Society.
Citation:
Jonsson F, Beke-Somfai T, Andréasson J, Nordén B (2013) Interactions of a Photochromic Spiropyran with Liposome Model Membranes. Langmuir 29: 2099–2103. Available: http://dx.doi.org/10.1021/la304867d.
Publisher:
American Chemical Society (ACS)
Journal:
Langmuir
Issue Date:
19-Feb-2013
DOI:
10.1021/la304867d
PubMed ID:
23379890
Type:
Article
ISSN:
0743-7463; 1520-5827
Sponsors:
The authors gratefully acknowledge the help with synthesis by Dr. Shiming Li. This work was funded by the King Abdullah University of Science and Technology (KAUST Kuk No1) and by the European Research Council (ERC).
Appears in Collections:
Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorJonsson, Fabianen
dc.contributor.authorBeke-Somfai, Tamásen
dc.contributor.authorAndréasson, Joakimen
dc.contributor.authorNordén, Bengten
dc.date.accessioned2016-02-25T13:33:41Zen
dc.date.available2016-02-25T13:33:41Zen
dc.date.issued2013-02-19en
dc.identifier.citationJonsson F, Beke-Somfai T, Andréasson J, Nordén B (2013) Interactions of a Photochromic Spiropyran with Liposome Model Membranes. Langmuir 29: 2099–2103. Available: http://dx.doi.org/10.1021/la304867d.en
dc.identifier.issn0743-7463en
dc.identifier.issn1520-5827en
dc.identifier.pmid23379890en
dc.identifier.doi10.1021/la304867den
dc.identifier.urihttp://hdl.handle.net/10754/598643en
dc.description.abstractThe interactions between anionic or zwitterionic liposomes and a water-soluble, DNA-binding photochromic spiropyran are studied using UV/vis absorption and linear dichroism (LD) spectroscopy. The spectral characteristics as well as the kinetics of the thermal isomerization process in the absence and presence of the two different liposome types provide information about the environment and whether or not the spiropyran resides in the liposome membrane. By measuring LD on liposomes deformed and aligned by shear flow, further insight is obtained about interaction and binding geometry of the spiropyran at the lipid membranes. We show that the membrane interactions differ between the two types of liposomes used as well as the isomeric forms of the spiropyran photoswitch. © 2013 American Chemical Society.en
dc.description.sponsorshipThe authors gratefully acknowledge the help with synthesis by Dr. Shiming Li. This work was funded by the King Abdullah University of Science and Technology (KAUST Kuk No1) and by the European Research Council (ERC).en
dc.publisherAmerican Chemical Society (ACS)en
dc.titleInteractions of a Photochromic Spiropyran with Liposome Model Membranesen
dc.typeArticleen
dc.identifier.journalLangmuiren
dc.contributor.institutionChalmers University of Technology, Göteborg, Swedenen

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