DNA Duplex Length and Salt Concentration Dependence of Enthalpy−Entropy Compensation Parameters for DNA Melting

Handle URI:
http://hdl.handle.net/10754/598002
Title:
DNA Duplex Length and Salt Concentration Dependence of Enthalpy−Entropy Compensation Parameters for DNA Melting
Authors:
Starikov, E. B.; Nordén, Bengt
Abstract:
Systematical differential calorimetry experiments on DNA oligomers with different lengths and placed in water solutions with various added salt concentrations may, in principle, unravel important information about the structure and dynamics of the DNA and their water-counterion surrounding. With this in mind, to reinterpret the most recent results of calorimetric experiments on DNA oligomers of such a kind, the recent enthalpy-entropy compensation theory has been used. It is demonstrated that the application of the latter could enable direct estimation of thermodynamic parameters of the microphase transitions connected to the changes in DNA dynamical regimes versus the length of the biopolymers and the ionic strengths of their water solutions, and this calls for much more systematical experimental and theoretical studies in this field. © 2009 American Chemical Society.
Citation:
Starikov EB, Nordén B (2009) DNA Duplex Length and Salt Concentration Dependence of Enthalpy−Entropy Compensation Parameters for DNA Melting. J Phys Chem B 113: 11375–11377. Available: http://dx.doi.org/10.1021/jp903924j.
Publisher:
American Chemical Society (ACS)
Journal:
The Journal of Physical Chemistry B
Issue Date:
20-Aug-2009
DOI:
10.1021/jp903924j
PubMed ID:
19719257
Type:
Article
ISSN:
1520-6106; 1520-5207
Sponsors:
B.N. gratefully acknowledges the Award of 2008 from King Abdullah University of Science and Technology.
Appears in Collections:
Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorStarikov, E. B.en
dc.contributor.authorNordén, Bengten
dc.date.accessioned2016-02-25T13:10:45Zen
dc.date.available2016-02-25T13:10:45Zen
dc.date.issued2009-08-20en
dc.identifier.citationStarikov EB, Nordén B (2009) DNA Duplex Length and Salt Concentration Dependence of Enthalpy−Entropy Compensation Parameters for DNA Melting. J Phys Chem B 113: 11375–11377. Available: http://dx.doi.org/10.1021/jp903924j.en
dc.identifier.issn1520-6106en
dc.identifier.issn1520-5207en
dc.identifier.pmid19719257en
dc.identifier.doi10.1021/jp903924jen
dc.identifier.urihttp://hdl.handle.net/10754/598002en
dc.description.abstractSystematical differential calorimetry experiments on DNA oligomers with different lengths and placed in water solutions with various added salt concentrations may, in principle, unravel important information about the structure and dynamics of the DNA and their water-counterion surrounding. With this in mind, to reinterpret the most recent results of calorimetric experiments on DNA oligomers of such a kind, the recent enthalpy-entropy compensation theory has been used. It is demonstrated that the application of the latter could enable direct estimation of thermodynamic parameters of the microphase transitions connected to the changes in DNA dynamical regimes versus the length of the biopolymers and the ionic strengths of their water solutions, and this calls for much more systematical experimental and theoretical studies in this field. © 2009 American Chemical Society.en
dc.description.sponsorshipB.N. gratefully acknowledges the Award of 2008 from King Abdullah University of Science and Technology.en
dc.publisherAmerican Chemical Society (ACS)en
dc.titleDNA Duplex Length and Salt Concentration Dependence of Enthalpy−Entropy Compensation Parameters for DNA Meltingen
dc.typeArticleen
dc.identifier.journalThe Journal of Physical Chemistry Ben
dc.contributor.institutionKarlsruhe Institute of Technology, Campus North, Eggenstein-Leopoldshafen, Germanyen
dc.contributor.institutionChalmers University of Technology, Göteborg, Swedenen

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