Chiral PEPPSI Complexes: Synthesis, Characterization, and Application in Asymmetric Suzuki–Miyaura Coupling Reactions

Handle URI:
http://hdl.handle.net/10754/597774
Title:
Chiral PEPPSI Complexes: Synthesis, Characterization, and Application in Asymmetric Suzuki–Miyaura Coupling Reactions
Authors:
Benhamou, Laure; Besnard, Céline; Kündig, E. Peter
Abstract:
PEPPSI complexes incorporating chiral N-heterocyclic carbene (NHC) ligands based on 2,2-dimethyl-1-(o-substituted aryl)propan-1-amines were synthesized. Two complexes, with one saturated and one unsaturated NHC ligand, were structurally characterized. The chiral PEPPSI complexes were used in asymmetric Suzuki-Miyaura reactions, giving atropisomeric biaryl products in modest to good enantiomeric ratios. © 2013 American Chemical Society.
Citation:
Benhamou L, Besnard C, Kündig EP (2014) Chiral PEPPSI Complexes: Synthesis, Characterization, and Application in Asymmetric Suzuki–Miyaura Coupling Reactions. Organometallics 33: 260–266. Available: http://dx.doi.org/10.1021/om4009982.
Publisher:
American Chemical Society (ACS)
Journal:
Organometallics
Issue Date:
13-Jan-2014
DOI:
10.1021/om4009982
Type:
Article
ISSN:
0276-7333; 1520-6041
Sponsors:
We thank the Swiss National Science Foundation and the University of Geneva for financial support, Stephane Rosset and Prof. Alexandre Alexakis (Geneva) for the use of their supercritical fluid chromatography (SFC) equipment, and Prof. Luigi Cavallo (Salerno and KAUST) for advice on the calculation of %Vbur.
Appears in Collections:
Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorBenhamou, Laureen
dc.contributor.authorBesnard, Célineen
dc.contributor.authorKündig, E. Peteren
dc.date.accessioned2016-02-25T12:56:28Zen
dc.date.available2016-02-25T12:56:28Zen
dc.date.issued2014-01-13en
dc.identifier.citationBenhamou L, Besnard C, Kündig EP (2014) Chiral PEPPSI Complexes: Synthesis, Characterization, and Application in Asymmetric Suzuki–Miyaura Coupling Reactions. Organometallics 33: 260–266. Available: http://dx.doi.org/10.1021/om4009982.en
dc.identifier.issn0276-7333en
dc.identifier.issn1520-6041en
dc.identifier.doi10.1021/om4009982en
dc.identifier.urihttp://hdl.handle.net/10754/597774en
dc.description.abstractPEPPSI complexes incorporating chiral N-heterocyclic carbene (NHC) ligands based on 2,2-dimethyl-1-(o-substituted aryl)propan-1-amines were synthesized. Two complexes, with one saturated and one unsaturated NHC ligand, were structurally characterized. The chiral PEPPSI complexes were used in asymmetric Suzuki-Miyaura reactions, giving atropisomeric biaryl products in modest to good enantiomeric ratios. © 2013 American Chemical Society.en
dc.description.sponsorshipWe thank the Swiss National Science Foundation and the University of Geneva for financial support, Stephane Rosset and Prof. Alexandre Alexakis (Geneva) for the use of their supercritical fluid chromatography (SFC) equipment, and Prof. Luigi Cavallo (Salerno and KAUST) for advice on the calculation of %Vbur.en
dc.publisherAmerican Chemical Society (ACS)en
dc.titleChiral PEPPSI Complexes: Synthesis, Characterization, and Application in Asymmetric Suzuki–Miyaura Coupling Reactionsen
dc.typeArticleen
dc.identifier.journalOrganometallicsen
dc.contributor.institutionUniversite de Geneve, Geneve, Switzerlanden
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