Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors

Handle URI:
http://hdl.handle.net/10754/597719
Title:
Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors
Authors:
Tornatore, Laura; Sandomenico, Annamaria; Raimondo, Domenico; Low, Caroline; Rocci, Alberto; Tralau-Stewart, Cathy; Capece, Daria; D’Andrea, Daniel; Bua, Marco; Boyle, Eileen; van Duin, Mark; Zoppoli, Pietro; Jaxa-Chamiec, Albert; Thotakura, Anil K.; Dyson, Julian; Walker, Brian A.; Leonardi, Antonio; Chambery, Angela; Driessen, Christoph; Sonneveld, Pieter; Morgan, Gareth; Palumbo, Antonio; Tramontano, Anna; Rahemtulla, Amin; Ruvo, Menotti; Franzoso, Guido
Citation:
Tornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, et al. (2014) Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors. Cancer Cell 26: 938. Available: http://dx.doi.org/10.1016/j.ccell.2014.11.021.
Publisher:
Elsevier BV
Journal:
Cancer Cell
KAUST Grant Number:
KUK-I1-012-43
Issue Date:
Dec-2014
DOI:
10.1016/j.ccell.2014.11.021
Type:
Article
ISSN:
1535-6108
Sponsors:
We thank G. Inghirami, F. Dazzi, R. Orlowski, I. Kuiatse, L. Bergsagel, H. Auner, K. Parzych, and A. Karadimitris for cell lines; L. De Colibus, A. De Simone, E. Bellone, and M. Gambella for analytical or technical assistance; G. Cruciani for access to FLAP; and P. Omedè for primary PC samples. We also thank A. Iavarone for critical experimental advice and U. Siebenlist, K. Kelly, M. Lenardo, M. Pagano, H. Walczak, G. Acton, L. Busino, A. De Simone, and E. Tate for critical reading of the manuscript. The work was supported in part by Medical Research Council grants G0901436 and MR/L005069/1, NIH grants CA084040 and CA098583, Cancer Research UK grants A8839 and A15115, and an Imperial Innovations grant to G.F.; Project MERIT FIRB No. RBNE08NKH7_003 to M.R.; King Abdullah University of Science and Technology award KUK-I1-012-43 and PRIN 20108XYHJS to A.T.; and a PRIN 2009 grant to A.P.
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Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorTornatore, Lauraen
dc.contributor.authorSandomenico, Annamariaen
dc.contributor.authorRaimondo, Domenicoen
dc.contributor.authorLow, Carolineen
dc.contributor.authorRocci, Albertoen
dc.contributor.authorTralau-Stewart, Cathyen
dc.contributor.authorCapece, Dariaen
dc.contributor.authorD’Andrea, Danielen
dc.contributor.authorBua, Marcoen
dc.contributor.authorBoyle, Eileenen
dc.contributor.authorvan Duin, Marken
dc.contributor.authorZoppoli, Pietroen
dc.contributor.authorJaxa-Chamiec, Alberten
dc.contributor.authorThotakura, Anil K.en
dc.contributor.authorDyson, Julianen
dc.contributor.authorWalker, Brian A.en
dc.contributor.authorLeonardi, Antonioen
dc.contributor.authorChambery, Angelaen
dc.contributor.authorDriessen, Christophen
dc.contributor.authorSonneveld, Pieteren
dc.contributor.authorMorgan, Garethen
dc.contributor.authorPalumbo, Antonioen
dc.contributor.authorTramontano, Annaen
dc.contributor.authorRahemtulla, Aminen
dc.contributor.authorRuvo, Menottien
dc.contributor.authorFranzoso, Guidoen
dc.date.accessioned2016-02-25T12:55:28Zen
dc.date.available2016-02-25T12:55:28Zen
dc.date.issued2014-12en
dc.identifier.citationTornatore L, Sandomenico A, Raimondo D, Low C, Rocci A, et al. (2014) Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors. Cancer Cell 26: 938. Available: http://dx.doi.org/10.1016/j.ccell.2014.11.021.en
dc.identifier.issn1535-6108en
dc.identifier.doi10.1016/j.ccell.2014.11.021en
dc.identifier.urihttp://hdl.handle.net/10754/597719en
dc.description.sponsorshipWe thank G. Inghirami, F. Dazzi, R. Orlowski, I. Kuiatse, L. Bergsagel, H. Auner, K. Parzych, and A. Karadimitris for cell lines; L. De Colibus, A. De Simone, E. Bellone, and M. Gambella for analytical or technical assistance; G. Cruciani for access to FLAP; and P. Omedè for primary PC samples. We also thank A. Iavarone for critical experimental advice and U. Siebenlist, K. Kelly, M. Lenardo, M. Pagano, H. Walczak, G. Acton, L. Busino, A. De Simone, and E. Tate for critical reading of the manuscript. The work was supported in part by Medical Research Council grants G0901436 and MR/L005069/1, NIH grants CA084040 and CA098583, Cancer Research UK grants A8839 and A15115, and an Imperial Innovations grant to G.F.; Project MERIT FIRB No. RBNE08NKH7_003 to M.R.; King Abdullah University of Science and Technology award KUK-I1-012-43 and PRIN 20108XYHJS to A.T.; and a PRIN 2009 grant to A.P.en
dc.publisherElsevier BVen
dc.titleCancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitorsen
dc.typeArticleen
dc.identifier.journalCancer Cellen
kaust.grant.numberKUK-I1-012-43en
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