Handle URI:
http://hdl.handle.net/10754/597589
Title:
Antifouling Activity of Marine Natural Products
Authors:
Qian, Pei-Yuan; Xu, Sharon Ying
Abstract:
With the global ban of application of organotin-based marine coatings by International Maritime Organization in 2008, there is a practical and urgent need of identifying environmentally friendly low-toxic and nontoxic antifouling compounds for marine industries. Marine natural products have been considered as one of the most promising sources of antifouling compounds in recent years. In antifouling compound screening processes, bioassay systems often play most critical/vital roles in screening efforts. To meet various needs, a variety of bioassay systems have been developed and/or adopted in both research and commercial laboratories. In this chapter, we provide a brief outline of common bioassay procedures for both antimicrofouling and antimacrofouling assays, which can serve as a general guideline for setting up bioassay systems in laboratories engaged in antifouling compound screening. Some bioassay procedures currently practiced in various laboratories are not included in this book chapter for various reasons. Individual laboratories should modify bioassay protocols based on their research interests or needs. Nevertheless, we highly recommend the research laboratories to adapt high-throughput assays as much as possible for preliminary screening assays, followed by more complex bioassay processes using multiple target species. We argue strongly for studies in mode-of-action of antifouling compounds against settling propagules, which shall lead to discovery of molecular biomarkers (genes, proteins, receptors, or receptor system) and will allow us to design more targeted bioassay systems.
Citation:
Qian P-Y, Xu SY (2012) Antifouling Activity of Marine Natural Products. Handbook of Marine Natural Products: 749–821. Available: http://dx.doi.org/10.1007/978-90-481-3834-0_14.
Publisher:
Springer Science + Business Media
Journal:
Handbook of Marine Natural Products
Issue Date:
2012
DOI:
10.1007/978-90-481-3834-0_14
Type:
Book Chapter
Sponsors:
KAUST Global Collaborative Program
Appears in Collections:
Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorQian, Pei-Yuanen
dc.contributor.authorXu, Sharon Yingen
dc.date.accessioned2016-02-25T12:42:38Zen
dc.date.available2016-02-25T12:42:38Zen
dc.date.issued2012en
dc.identifier.citationQian P-Y, Xu SY (2012) Antifouling Activity of Marine Natural Products. Handbook of Marine Natural Products: 749–821. Available: http://dx.doi.org/10.1007/978-90-481-3834-0_14.en
dc.identifier.doi10.1007/978-90-481-3834-0_14en
dc.identifier.urihttp://hdl.handle.net/10754/597589en
dc.description.abstractWith the global ban of application of organotin-based marine coatings by International Maritime Organization in 2008, there is a practical and urgent need of identifying environmentally friendly low-toxic and nontoxic antifouling compounds for marine industries. Marine natural products have been considered as one of the most promising sources of antifouling compounds in recent years. In antifouling compound screening processes, bioassay systems often play most critical/vital roles in screening efforts. To meet various needs, a variety of bioassay systems have been developed and/or adopted in both research and commercial laboratories. In this chapter, we provide a brief outline of common bioassay procedures for both antimicrofouling and antimacrofouling assays, which can serve as a general guideline for setting up bioassay systems in laboratories engaged in antifouling compound screening. Some bioassay procedures currently practiced in various laboratories are not included in this book chapter for various reasons. Individual laboratories should modify bioassay protocols based on their research interests or needs. Nevertheless, we highly recommend the research laboratories to adapt high-throughput assays as much as possible for preliminary screening assays, followed by more complex bioassay processes using multiple target species. We argue strongly for studies in mode-of-action of antifouling compounds against settling propagules, which shall lead to discovery of molecular biomarkers (genes, proteins, receptors, or receptor system) and will allow us to design more targeted bioassay systems.en
dc.description.sponsorshipKAUST Global Collaborative Programen
dc.publisherSpringer Science + Business Mediaen
dc.titleAntifouling Activity of Marine Natural Productsen
dc.typeBook Chapteren
dc.identifier.journalHandbook of Marine Natural Productsen
dc.contributor.institutionKAUST Global Collaborative Program, Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, Chinaen
All Items in KAUST are protected by copyright, with all rights reserved, unless otherwise indicated.