Handle URI:
http://hdl.handle.net/10754/596811
Title:
PICMI: mapping point mutations on genomes.
Authors:
Le Pera, Loredana; Marcatili, Paolo; Tramontano, Anna
Abstract:
MOTIVATION: Several international collaborations and local projects are producing extensive catalogues of genomic variations that are supplementing existing collections such as the OMIM catalogue. The flood of this type of data will keep increasing and, especially, it will be relevant to a wider user base, including not only molecular biologists, geneticists and bioinformaticians, but also clinical researchers. Mapping the observed variations, sometimes only described at the amino acid level, on a genome, identifying whether they affect a gene and-if so-whether they also affect different isoforms of the same gene, is a time consuming and often frustrating task. RESULTS: The PICMI server is an easy to use tool for quickly mapping one or more amino acid or nucleotide variations on a genome and its products, including alternatively spliced isoforms. AVAILABILITY: The server is available at www.biocomputing.it/picmi.
Citation:
Le Pera L, Marcatili P, Tramontano A (2010) PICMI: mapping point mutations on genomes. Bioinformatics 26: 2904–2905. Available: http://dx.doi.org/10.1093/bioinformatics/btq547.
Publisher:
Oxford University Press (OUP)
Journal:
Bioinformatics
KAUST Grant Number:
KUK-I1-012-43
Issue Date:
12-Oct-2010
DOI:
10.1093/bioinformatics/btq547
PubMed ID:
20940168
PubMed Central ID:
PMC2971578
Type:
Article
ISSN:
1367-4803; 1460-2059
Sponsors:
KAUST (Award N. KUK-I1-012-43) and FIRB (Italbionet and Proteomica).
Appears in Collections:
Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorLe Pera, Loredanaen
dc.contributor.authorMarcatili, Paoloen
dc.contributor.authorTramontano, Annaen
dc.date.accessioned2016-02-21T08:51:08Zen
dc.date.available2016-02-21T08:51:08Zen
dc.date.issued2010-10-12en
dc.identifier.citationLe Pera L, Marcatili P, Tramontano A (2010) PICMI: mapping point mutations on genomes. Bioinformatics 26: 2904–2905. Available: http://dx.doi.org/10.1093/bioinformatics/btq547.en
dc.identifier.issn1367-4803en
dc.identifier.issn1460-2059en
dc.identifier.pmid20940168en
dc.identifier.doi10.1093/bioinformatics/btq547en
dc.identifier.urihttp://hdl.handle.net/10754/596811en
dc.description.abstractMOTIVATION: Several international collaborations and local projects are producing extensive catalogues of genomic variations that are supplementing existing collections such as the OMIM catalogue. The flood of this type of data will keep increasing and, especially, it will be relevant to a wider user base, including not only molecular biologists, geneticists and bioinformaticians, but also clinical researchers. Mapping the observed variations, sometimes only described at the amino acid level, on a genome, identifying whether they affect a gene and-if so-whether they also affect different isoforms of the same gene, is a time consuming and often frustrating task. RESULTS: The PICMI server is an easy to use tool for quickly mapping one or more amino acid or nucleotide variations on a genome and its products, including alternatively spliced isoforms. AVAILABILITY: The server is available at www.biocomputing.it/picmi.en
dc.description.sponsorshipKAUST (Award N. KUK-I1-012-43) and FIRB (Italbionet and Proteomica).en
dc.publisherOxford University Press (OUP)en
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttp://creativecommons.org/licenses/by-nc/2.0/uk/en
dc.subject.meshPoint Mutationen
dc.subject.meshGenomeen
dc.subject.meshSoftwareen
dc.titlePICMI: mapping point mutations on genomes.en
dc.typeArticleen
dc.identifier.journalBioinformaticsen
dc.identifier.pmcidPMC2971578en
dc.contributor.institutionUniversita degli Studi di Roma La Sapienza, Rome, Italyen
dc.contributor.institutionUniversita degli Studi di Roma La Sapienza, Rome, Italyen
kaust.grant.numberKUK-I1-012-43en

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