Mapping three-dimensional temperature in microfluidic chip.

Handle URI:
http://hdl.handle.net/10754/596800
Title:
Mapping three-dimensional temperature in microfluidic chip.
Authors:
Wu, Jinbo; Kwok, Tsz Yan; Li, Xiaolin; Cao, Wenbin; Wang, Yu; Huang, Junying; Hong, Yaying; Zhang, Dongen; Wen, Weijia
Abstract:
Three-dimensional (3D) temperature mapping method with high spatial resolution and acquisition rate is of vital importance in evaluating thermal processes in micro-environment. We have synthesized a new temperature-sensitive functional material (Rhodamine B functionalized Polydimethylsiloxane). By performing optical sectioning of this material, we established an advanced method for visualizing the micro-scale 3D thermal distribution inside microfluidic chip with down to 10 ms temporal resolution and 2 ~ 6 °C temperature resolution depending the capture parameters. This method is successfully applied to monitor the local temperature variation throughout micro-droplet heat transfer process and further reveal exothermic nanoliter droplet reactions to be unique and milder than bench-top experiment.
Citation:
Wu J, Kwok TY, Li X, Cao W, Wang Y, et al. (2013) Mapping three-dimensional temperature in microfluidic chip. Scientific Reports 3. Available: http://dx.doi.org/10.1038/srep03321.
Publisher:
Nature Publishing Group
Journal:
Scientific Reports
KAUST Grant Number:
SA-C0040/UK-C0016
Issue Date:
25-Nov-2013
DOI:
10.1038/srep03321
PubMed ID:
24276475
PubMed Central ID:
PMC3839638
Type:
Article
ISSN:
2045-2322
Sponsors:
The authors acknowledge the financial support provided by the Hong Kong Research Grants Council Grant No. HKUST 604710 and HKUST 605411. This publication is based on work partially supported by Award No. SA-C0040/UK-C0016 made by King Abdullah University of Science and Technology (KAUST).
Appears in Collections:
Publications Acknowledging KAUST Support

Full metadata record

DC FieldValue Language
dc.contributor.authorWu, Jinboen
dc.contributor.authorKwok, Tsz Yanen
dc.contributor.authorLi, Xiaolinen
dc.contributor.authorCao, Wenbinen
dc.contributor.authorWang, Yuen
dc.contributor.authorHuang, Junyingen
dc.contributor.authorHong, Yayingen
dc.contributor.authorZhang, Dongenen
dc.contributor.authorWen, Weijiaen
dc.date.accessioned2016-02-21T08:50:56Zen
dc.date.available2016-02-21T08:50:56Zen
dc.date.issued2013-11-25en
dc.identifier.citationWu J, Kwok TY, Li X, Cao W, Wang Y, et al. (2013) Mapping three-dimensional temperature in microfluidic chip. Scientific Reports 3. Available: http://dx.doi.org/10.1038/srep03321.en
dc.identifier.issn2045-2322en
dc.identifier.pmid24276475en
dc.identifier.doi10.1038/srep03321en
dc.identifier.urihttp://hdl.handle.net/10754/596800en
dc.description.abstractThree-dimensional (3D) temperature mapping method with high spatial resolution and acquisition rate is of vital importance in evaluating thermal processes in micro-environment. We have synthesized a new temperature-sensitive functional material (Rhodamine B functionalized Polydimethylsiloxane). By performing optical sectioning of this material, we established an advanced method for visualizing the micro-scale 3D thermal distribution inside microfluidic chip with down to 10 ms temporal resolution and 2 ~ 6 °C temperature resolution depending the capture parameters. This method is successfully applied to monitor the local temperature variation throughout micro-droplet heat transfer process and further reveal exothermic nanoliter droplet reactions to be unique and milder than bench-top experiment.en
dc.description.sponsorshipThe authors acknowledge the financial support provided by the Hong Kong Research Grants Council Grant No. HKUST 604710 and HKUST 605411. This publication is based on work partially supported by Award No. SA-C0040/UK-C0016 made by King Abdullah University of Science and Technology (KAUST).en
dc.publisherNature Publishing Groupen
dc.rightsThis work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visiten
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/en
dc.titleMapping three-dimensional temperature in microfluidic chip.en
dc.typeArticleen
dc.identifier.journalScientific Reportsen
dc.identifier.pmcidPMC3839638en
dc.contributor.institutionDepartment of Physics, the Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.en
kaust.grant.numberSA-C0040/UK-C0016en
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