Integration of fractal biosensor in a digital microfluidic platform

Handle URI:
http://hdl.handle.net/10754/594971
Title:
Integration of fractal biosensor in a digital microfluidic platform
Authors:
Mashraei, Yousof; Sivashankar, Shilpa; Buttner, Ulrich; Salama, Khaled N. ( 0000-0001-7742-1282 )
Abstract:
Fractal capacitive electrodes have been successfully integrated into a digital microfluidic open-platform. These electrodes perform actuation and withstand voltages up to 300V without insulation-layer breakdown. They were used to quantify the concentration levels of C-reactive protein (CRP) to determine the risk of cardiovascular disease. The capacitance increased sevenfold and stabilized in less than 5 minutes. The sensor shows a decreasing trend of capacitance readouts with the increase of concentrations. The same immunoassay was tested with untreated electrodes and showed no significant response, which suggests that immobilization was necessary. This configuration allows the electrodes to be used as biosensors.
KAUST Department:
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Publisher:
Institute of Electrical and Electronics Engineers (IEEE)
Journal:
2015 IEEE SENSORS
Conference/Event name:
SENSORS, 2015 IEEE
Issue Date:
1-Nov-2015
DOI:
10.1109/ICSENS.2015.7370497
Type:
Conference Paper
Additional Links:
http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=7370497
Appears in Collections:
Conference Papers; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorMashraei, Yousofen
dc.contributor.authorSivashankar, Shilpaen
dc.contributor.authorButtner, Ulrichen
dc.contributor.authorSalama, Khaled N.en
dc.date.accessioned2016-01-27T13:05:44Zen
dc.date.available2016-01-27T13:05:44Zen
dc.date.issued2015-11-01en
dc.identifier.doi10.1109/ICSENS.2015.7370497en
dc.identifier.urihttp://hdl.handle.net/10754/594971en
dc.description.abstractFractal capacitive electrodes have been successfully integrated into a digital microfluidic open-platform. These electrodes perform actuation and withstand voltages up to 300V without insulation-layer breakdown. They were used to quantify the concentration levels of C-reactive protein (CRP) to determine the risk of cardiovascular disease. The capacitance increased sevenfold and stabilized in less than 5 minutes. The sensor shows a decreasing trend of capacitance readouts with the increase of concentrations. The same immunoassay was tested with untreated electrodes and showed no significant response, which suggests that immobilization was necessary. This configuration allows the electrodes to be used as biosensors.en
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)en
dc.relation.urlhttp://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=7370497en
dc.rights(c) 2015 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works.en
dc.subjectBiosensoren
dc.subjectC-Reactive Proteinen
dc.subjectCRPen
dc.subjectDigital Microfluidicen
dc.subjectEWODen
dc.subjectElectrowetting On Dielectricen
dc.subjectFractal Capacitoren
dc.titleIntegration of fractal biosensor in a digital microfluidic platformen
dc.typeConference Paperen
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Divisionen
dc.identifier.journal2015 IEEE SENSORSen
dc.conference.date1-4 Nov. 2015en
dc.conference.nameSENSORS, 2015 IEEEen
dc.conference.locationBusan, South Koreaen
dc.eprint.versionPost-printen
kaust.authorMashraei, Yousofen
kaust.authorSivashankar, Shilpaen
kaust.authorButtner, Ulrichen
kaust.authorSalama, Khaled N.en
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