Dysprosium-containing layered double hydroxides nanoparticles intercalated with biologically active species as an approach for theranostic systems

Handle URI:
http://hdl.handle.net/10754/583061
Title:
Dysprosium-containing layered double hydroxides nanoparticles intercalated with biologically active species as an approach for theranostic systems
Authors:
Arratia-Quijada, Jenny; Sánchez Jiménez, Cecilia; Gurinov, Andrei; Pérez Centeno, Armando; Ceja Andrade, Israel; Carbajal Arízaga, Gregorio Guadalupe ( 0000-0003-3120-0243 )
Abstract:
A layered double hydroxide structure including dysprosium cations was prepared by co-precipitation. The nanoparticles showed a linear relationship with the reciprocal relaxation spin-lattice (T1) time of water protons which is reflected as contrast in aqueous suspensions analyzed by magnetic resonance imaging. The interlayer space of dysprosium containing LDH was successfully intercalated with folate, ibuprofen and gallate ions, which are key molecules for recognition of some cancer cells and treatment of diseases. The paramagnetic property of the dysprosium-containing LDH detected in this work beside the ability to transport drugs open up the opportunity to design theranostic materials in a single crystal phase with nanometric dimensions.
KAUST Department:
Nuclear Magnetic Resonance Core Lab
Citation:
Dysprosium-containing layered double hydroxides nanoparticles intercalated with biologically active species as an approach for theranostic systems 2016, 203:7 Materials Science and Engineering: B
Publisher:
Elsevier BV
Journal:
Materials Science and Engineering: B
Issue Date:
23-Oct-2015
DOI:
10.1016/j.mseb.2015.10.004
Type:
Article
ISSN:
09215107
Additional Links:
http://linkinghub.elsevier.com/retrieve/pii/S0921510715002287
Appears in Collections:
Articles

Full metadata record

DC FieldValue Language
dc.contributor.authorArratia-Quijada, Jennyen
dc.contributor.authorSánchez Jiménez, Ceciliaen
dc.contributor.authorGurinov, Andreien
dc.contributor.authorPérez Centeno, Armandoen
dc.contributor.authorCeja Andrade, Israelen
dc.contributor.authorCarbajal Arízaga, Gregorio Guadalupeen
dc.date.accessioned2015-12-01T13:33:16Zen
dc.date.available2015-12-01T13:33:16Zen
dc.date.issued2015-10-23en
dc.identifier.citationDysprosium-containing layered double hydroxides nanoparticles intercalated with biologically active species as an approach for theranostic systems 2016, 203:7 Materials Science and Engineering: Ben
dc.identifier.issn09215107en
dc.identifier.doi10.1016/j.mseb.2015.10.004en
dc.identifier.urihttp://hdl.handle.net/10754/583061en
dc.description.abstractA layered double hydroxide structure including dysprosium cations was prepared by co-precipitation. The nanoparticles showed a linear relationship with the reciprocal relaxation spin-lattice (T1) time of water protons which is reflected as contrast in aqueous suspensions analyzed by magnetic resonance imaging. The interlayer space of dysprosium containing LDH was successfully intercalated with folate, ibuprofen and gallate ions, which are key molecules for recognition of some cancer cells and treatment of diseases. The paramagnetic property of the dysprosium-containing LDH detected in this work beside the ability to transport drugs open up the opportunity to design theranostic materials in a single crystal phase with nanometric dimensions.en
dc.language.isoenen
dc.publisherElsevier BVen
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0921510715002287en
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in Materials Science and Engineering: B. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Materials Science and Engineering: B, 23 October 2015. DOI: 10.1016/j.mseb.2015.10.004en
dc.subjectHydroxidesen
dc.subjectMRIen
dc.subjectContrast agenten
dc.subjectCarrieren
dc.subjectDrugen
dc.titleDysprosium-containing layered double hydroxides nanoparticles intercalated with biologically active species as an approach for theranostic systemsen
dc.typeArticleen
dc.contributor.departmentNuclear Magnetic Resonance Core Laben
dc.identifier.journalMaterials Science and Engineering: Ben
dc.eprint.versionPost-printen
dc.contributor.institutionDepartamento de Ciencias de la Salud, Centro Universitario Tonalá, Universidad de Guadalajara, Av. Nuevo Periférico No. 555, C.P. 48525, Tonalá, Jalisco, Mexicoen
dc.contributor.institutionDepartamento de Química, Universidad de Guadalajara, Boulevard Marcelino García Barragán 1421, C.P. 44430, Guadalajara, Jalisco, Mexicoen
dc.contributor.institutionResearch Resources Center for Magnetic Resonance, St. Petersburg State University, Universitetskiy pr. 26, 198504 St. Petersburg, Russiaen
dc.contributor.institutionDepartamento de Física, Universidad de Guadalajara, Boulevard Marcelino García Barragán 1421, C.P. 44430, Guadalajara, Jalisco, Mexicoen
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)en
kaust.authorGurinov, Andreien
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