Single-cell technologies in environmental omics

Handle URI:
http://hdl.handle.net/10754/581690
Title:
Single-cell technologies in environmental omics
Authors:
Kodzius, Rimantas ( 0000-0001-9417-8894 ) ; Gojobori, Takashi ( 0000-0001-7850-1743 )
Abstract:
Environmental studies are primarily done by culturing isolated microorganisms or by amplifying and sequencing conserved genes. Difficulties understanding the complexity of large numbers of various microorganisms in an environment led to the development of techniques to enrich specific microorganisms for upstream analysis, ultimately leading to single-cell isolation and analyses. We discuss the significance of single-cell technologies in omics studies with focus on metagenomics and metatranscriptomics. We propose that by reducing sample heterogeneity using single-cell genomics, metaomic studies can be simplified.
KAUST Department:
Computational Bioscience Research Center (CBRC); Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division; Biological and Environmental Sciences and Engineering (BESE) Division
Citation:
Single-cell technologies in environmental omics 2015 Gene
Publisher:
Elsevier BV
Journal:
Gene
Issue Date:
22-Oct-2015
DOI:
10.1016/j.gene.2015.10.031
Type:
Article
ISSN:
03781119
Additional Links:
http://linkinghub.elsevier.com/retrieve/pii/S0378111915012391
Appears in Collections:
Articles; Computational Bioscience Research Center (CBRC); Biological and Environmental Sciences and Engineering (BESE) Division; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorKodzius, Rimantasen
dc.contributor.authorGojobori, Takashien
dc.date.accessioned2015-11-04T06:40:17Zen
dc.date.available2015-11-04T06:40:17Zen
dc.date.issued2015-10-22en
dc.identifier.citationSingle-cell technologies in environmental omics 2015 Geneen
dc.identifier.issn03781119en
dc.identifier.doi10.1016/j.gene.2015.10.031en
dc.identifier.urihttp://hdl.handle.net/10754/581690en
dc.description.abstractEnvironmental studies are primarily done by culturing isolated microorganisms or by amplifying and sequencing conserved genes. Difficulties understanding the complexity of large numbers of various microorganisms in an environment led to the development of techniques to enrich specific microorganisms for upstream analysis, ultimately leading to single-cell isolation and analyses. We discuss the significance of single-cell technologies in omics studies with focus on metagenomics and metatranscriptomics. We propose that by reducing sample heterogeneity using single-cell genomics, metaomic studies can be simplified.en
dc.language.isoenen
dc.publisherElsevier BVen
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0378111915012391en
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in Gene. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Gene, 22 October 2015. DOI: 10.1016/j.gene.2015.10.031en
dc.subjectMetagenomicsen
dc.subjectHeterogeneityen
dc.subjectSequencingen
dc.subjectMicrodropleten
dc.subjectFACSen
dc.titleSingle-cell technologies in environmental omicsen
dc.typeArticleen
dc.contributor.departmentComputational Bioscience Research Center (CBRC)en
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Divisionen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.identifier.journalGeneen
dc.eprint.versionPost-printen
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)en
kaust.authorKodzius, Rimantasen
kaust.authorGojobori, Takashien
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