The genome of Aiptasia, a sea anemone model for coral symbiosis

Handle URI:
http://hdl.handle.net/10754/576855
Title:
The genome of Aiptasia, a sea anemone model for coral symbiosis
Authors:
Baumgarten, Sebastian ( 0000-0003-2646-7699 ) ; Simakov, Oleg; Esherick, Lisl Y.; Liew, Yi Jin ( 0000-0003-2553-8870 ) ; Lehnert, Erik M.; Michell, Craig; Li, Yong ( 0000-0003-2609-2401 ) ; Hambleton, Elizabeth A.; Guse, Annika; Oates, Matt E.; Gough, Julian; Weis, Virginia M.; Aranda, Manuel ( 0000-0001-6673-016X ) ; Pringle, John R.; Voolstra, Christian R. ( 0000-0003-4555-3795 )
Abstract:
The most diverse marine ecosystems, coral reefs, depend upon a functional symbiosis between a cnidarian animal host (the coral) and intracellular photosynthetic dinoflagellate algae. The molecular and cellular mechanisms underlying this endosymbiosis are not well understood, in part because of the difficulties of experimental work with corals. The small sea anemone Aiptasia provides a tractable laboratory model for investigating these mechanisms. Here we report on the assembly and analysis of the Aiptasia genome, which will provide a foundation for future studies and has revealed several features that may be key to understanding the evolution and function of the endosymbiosis. These features include genomic rearrangements and taxonomically restricted genes that may be functionally related to the symbiosis, aspects of host dependence on alga-derived nutrients, a novel and expanded cnidarian-specific family of putative pattern-recognition receptors that might be involved in the animal–algal interactions, and extensive lineage-specific horizontal gene transfer. Extensive integration of genes of prokaryotic origin, including genes for antimicrobial peptides, presumably reflects an intimate association of the animal–algal pair also with its prokaryotic microbiome.
KAUST Department:
Red Sea Research Center (RSRC); Biological and Environmental Sciences and Engineering (BESE) Division
Citation:
The genome of Aiptasia, a sea anemone model for coral symbiosis 2015:201513318 Proceedings of the National Academy of Sciences
Publisher:
Proceedings of the National Academy of Sciences
Journal:
Proceedings of the National Academy of Sciences
Issue Date:
31-Aug-2015
DOI:
10.1073/pnas.1513318112
Type:
Article
ISSN:
0027-8424; 1091-6490
Additional Links:
http://www.pnas.org/lookup/doi/10.1073/pnas.1513318112
Appears in Collections:
Articles; Red Sea Research Center (RSRC); Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorBaumgarten, Sebastianen
dc.contributor.authorSimakov, Olegen
dc.contributor.authorEsherick, Lisl Y.en
dc.contributor.authorLiew, Yi Jinen
dc.contributor.authorLehnert, Erik M.en
dc.contributor.authorMichell, Craigen
dc.contributor.authorLi, Yongen
dc.contributor.authorHambleton, Elizabeth A.en
dc.contributor.authorGuse, Annikaen
dc.contributor.authorOates, Matt E.en
dc.contributor.authorGough, Julianen
dc.contributor.authorWeis, Virginia M.en
dc.contributor.authorAranda, Manuelen
dc.contributor.authorPringle, John R.en
dc.contributor.authorVoolstra, Christian R.en
dc.date.accessioned2015-09-06T13:50:34Zen
dc.date.available2015-09-06T13:50:34Zen
dc.date.issued2015-08-31en
dc.identifier.citationThe genome of Aiptasia, a sea anemone model for coral symbiosis 2015:201513318 Proceedings of the National Academy of Sciencesen
dc.identifier.issn0027-8424en
dc.identifier.issn1091-6490en
dc.identifier.doi10.1073/pnas.1513318112en
dc.identifier.urihttp://hdl.handle.net/10754/576855en
dc.description.abstractThe most diverse marine ecosystems, coral reefs, depend upon a functional symbiosis between a cnidarian animal host (the coral) and intracellular photosynthetic dinoflagellate algae. The molecular and cellular mechanisms underlying this endosymbiosis are not well understood, in part because of the difficulties of experimental work with corals. The small sea anemone Aiptasia provides a tractable laboratory model for investigating these mechanisms. Here we report on the assembly and analysis of the Aiptasia genome, which will provide a foundation for future studies and has revealed several features that may be key to understanding the evolution and function of the endosymbiosis. These features include genomic rearrangements and taxonomically restricted genes that may be functionally related to the symbiosis, aspects of host dependence on alga-derived nutrients, a novel and expanded cnidarian-specific family of putative pattern-recognition receptors that might be involved in the animal–algal interactions, and extensive lineage-specific horizontal gene transfer. Extensive integration of genes of prokaryotic origin, including genes for antimicrobial peptides, presumably reflects an intimate association of the animal–algal pair also with its prokaryotic microbiome.en
dc.language.isoenen
dc.publisherProceedings of the National Academy of Sciencesen
dc.relation.urlhttp://www.pnas.org/lookup/doi/10.1073/pnas.1513318112en
dc.rightsArchived with thanks to Proceedings of the National Academy of Sciences. Freely available online through the PNAS open access option.en
dc.subjectcoral reefsen
dc.subjectendosymbiosisen
dc.subjecthorizontal gene transferen
dc.subjectdinoflagellateen
dc.subjectpattern-recognition receptorsen
dc.titleThe genome of Aiptasia, a sea anemone model for coral symbiosisen
dc.typeArticleen
dc.contributor.departmentRed Sea Research Center (RSRC)en
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.identifier.journalProceedings of the National Academy of Sciencesen
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionCentre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germanyen
dc.contributor.institutionDepartment of Genetics, Stanford University School of Medicine, Stanford, CA 94305en
dc.contributor.institutionDepartment of Computer Science, University of Bristol, Bristol BS8 1UB, United Kingdomen
dc.contributor.institutionDepartment of Integrative Biology, Oregon State University, Corvallis, OR 97331en
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)en
kaust.authorBaumgarten, Sebastianen
kaust.authorLiew, Yi Jinen
kaust.authorMichell, Craigen
kaust.authorLi, Yongen
kaust.authorAranda, Manuelen
kaust.authorVoolstra, Christian R.en
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