Chapter 11 Unexpected Turns and Twists in Structure/Function of PR-Proteins that Connect Energy Metabolism and Immunity

Handle URI:
http://hdl.handle.net/10754/565959
Title:
Chapter 11 Unexpected Turns and Twists in Structure/Function of PR-Proteins that Connect Energy Metabolism and Immunity
Authors:
Narasimhan, Meena L.; Bressan, Ray Anthony; D'Urzo, Matilde Paino; Jenks, Matthew A.; Mengiste, Tesfaye
Abstract:
Innate immunity in plants is manifested by a complex array of antimicrobial processes that includes induction of sets of pathogenesis-related (PR) proteins. The availability of genomic data has made clear that each PR-protein family in a species is represented by several genes. Microarray data in public databases show that in most families, including the PR-5 family surveyed here, the expression of only few family members is defense associated. Genetic studies show that depending on their nutrient acquisition strategy, pathogens induce distinct but overlapping sets of PR genes, suggesting a connection to energy or resource allocation. PR-5 proteins have a clearly recognizable structure that is referred to as the thaumatin (THN) domain, which can be overlapped with mammalian Complement 1q-tumor necrosis factor (C1q-TNF) domains such as that of the mammalian hormone adiponectin. The occurrence of THN domain proteins is widespread. Similarities between THN domain proteins and mammalian C1q-TNF family proteins include their ligands and their subcellular locations. Osmotin (tobacco PR-5c) regulates energy balance signaling in mammalian cells by interaction with adiponectin receptors by a pathway that shares components with plant energy and stress signaling pathways. These data suggest additional roles for PR-5 proteins, as scaffolds and/or in signaling, particularly in regulating energy balance. © 2009 Elsevier Ltd. All rights reserved.
KAUST Department:
Center for Desert Agriculture
Publisher:
Elsevier BV
Journal:
Advances in Botanical Research
Issue Date:
2009
DOI:
10.1016/S0065-2296(09)51011-7
Type:
Article
ISSN:
00652296
Appears in Collections:
Articles; Center for Desert Agriculture

Full metadata record

DC FieldValue Language
dc.contributor.authorNarasimhan, Meena L.en
dc.contributor.authorBressan, Ray Anthonyen
dc.contributor.authorD'Urzo, Matilde Painoen
dc.contributor.authorJenks, Matthew A.en
dc.contributor.authorMengiste, Tesfayeen
dc.date.accessioned2015-08-12T08:56:53Zen
dc.date.available2015-08-12T08:56:53Zen
dc.date.issued2009en
dc.identifier.issn00652296en
dc.identifier.doi10.1016/S0065-2296(09)51011-7en
dc.identifier.urihttp://hdl.handle.net/10754/565959en
dc.description.abstractInnate immunity in plants is manifested by a complex array of antimicrobial processes that includes induction of sets of pathogenesis-related (PR) proteins. The availability of genomic data has made clear that each PR-protein family in a species is represented by several genes. Microarray data in public databases show that in most families, including the PR-5 family surveyed here, the expression of only few family members is defense associated. Genetic studies show that depending on their nutrient acquisition strategy, pathogens induce distinct but overlapping sets of PR genes, suggesting a connection to energy or resource allocation. PR-5 proteins have a clearly recognizable structure that is referred to as the thaumatin (THN) domain, which can be overlapped with mammalian Complement 1q-tumor necrosis factor (C1q-TNF) domains such as that of the mammalian hormone adiponectin. The occurrence of THN domain proteins is widespread. Similarities between THN domain proteins and mammalian C1q-TNF family proteins include their ligands and their subcellular locations. Osmotin (tobacco PR-5c) regulates energy balance signaling in mammalian cells by interaction with adiponectin receptors by a pathway that shares components with plant energy and stress signaling pathways. These data suggest additional roles for PR-5 proteins, as scaffolds and/or in signaling, particularly in regulating energy balance. © 2009 Elsevier Ltd. All rights reserved.en
dc.publisherElsevier BVen
dc.titleChapter 11 Unexpected Turns and Twists in Structure/Function of PR-Proteins that Connect Energy Metabolism and Immunityen
dc.typeArticleen
dc.contributor.departmentCenter for Desert Agricultureen
dc.identifier.journalAdvances in Botanical Researchen
dc.contributor.institutionWorld Class University Program, Gyeonsang National University, South Koreaen
dc.contributor.institutionDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907, United Statesen
dc.contributor.institutionDepartment of Botany and Plant Pathology, Purdue University, West Lafayette, IN 47907, United Statesen
kaust.authorBressan, Ray Anthonyen
kaust.authorNarasimhan, Meena L.en
kaust.authorD'Urzo, Matilde Painoen
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