Improved detection limits of bacterial endotoxins using new type of planar interdigital sensors

Handle URI:
http://hdl.handle.net/10754/564615
Title:
Improved detection limits of bacterial endotoxins using new type of planar interdigital sensors
Authors:
Syaifudin, A. R Mohd; Zia, Asif I.; Mukhopadhyay, Subhas Chandra; Yu, Paklam; Gooneratne, Chinthaka Pasan; Kosel, Jürgen ( 0000-0002-8998-8275 )
Abstract:
New types of planar interdigital sensors were fabricated by photolithography and etching techniques on a Silicon/Silicon Dioxide (Si/SiO2) wafer (single side polished). The sensors were then coated with APTES (3-aminopropyltrietoxysilane) a cross linker used to bind Polymyxin B (PmB) molecules on electrodes surface. PmB is an antimicrobial peptide produced by the Gram-positive bacterium-Bacillus which has specific binding properties to Lipopolysaccharide (LPS). This paper will discuss the fabrication process, coating and immobilization procedures and analysis of sensors' performance based on Impedance Spectroscopy method. The sensor sensitivity was compared to standard ToxinSensor Chromogenic LAL Endotoxin Assay Kit for verification. © 2012 IEEE.
KAUST Department:
Sensing, Magnetism and Microsystems Lab; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division; Electrical Engineering Program
Publisher:
Institute of Electrical and Electronics Engineers (IEEE)
Journal:
2012 IEEE Sensors
Conference/Event name:
11th IEEE SENSORS 2012 Conference
Issue Date:
Oct-2012
DOI:
10.1109/ICSENS.2012.6411193
Type:
Conference Paper
ISBN:
9781457717659
Appears in Collections:
Conference Papers; Electrical Engineering Program; Sensing, Magnetism and Microsystems Lab; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorSyaifudin, A. R Mohden
dc.contributor.authorZia, Asif I.en
dc.contributor.authorMukhopadhyay, Subhas Chandraen
dc.contributor.authorYu, Paklamen
dc.contributor.authorGooneratne, Chinthaka Pasanen
dc.contributor.authorKosel, Jürgenen
dc.date.accessioned2015-08-04T07:05:11Zen
dc.date.available2015-08-04T07:05:11Zen
dc.date.issued2012-10en
dc.identifier.isbn9781457717659en
dc.identifier.doi10.1109/ICSENS.2012.6411193en
dc.identifier.urihttp://hdl.handle.net/10754/564615en
dc.description.abstractNew types of planar interdigital sensors were fabricated by photolithography and etching techniques on a Silicon/Silicon Dioxide (Si/SiO2) wafer (single side polished). The sensors were then coated with APTES (3-aminopropyltrietoxysilane) a cross linker used to bind Polymyxin B (PmB) molecules on electrodes surface. PmB is an antimicrobial peptide produced by the Gram-positive bacterium-Bacillus which has specific binding properties to Lipopolysaccharide (LPS). This paper will discuss the fabrication process, coating and immobilization procedures and analysis of sensors' performance based on Impedance Spectroscopy method. The sensor sensitivity was compared to standard ToxinSensor Chromogenic LAL Endotoxin Assay Kit for verification. © 2012 IEEE.en
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)en
dc.titleImproved detection limits of bacterial endotoxins using new type of planar interdigital sensorsen
dc.typeConference Paperen
dc.contributor.departmentSensing, Magnetism and Microsystems Laben
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Divisionen
dc.contributor.departmentElectrical Engineering Programen
dc.identifier.journal2012 IEEE Sensorsen
dc.conference.date28 October 2012 through 31 October 2012en
dc.conference.name11th IEEE SENSORS 2012 Conferenceen
dc.conference.locationTaipeien
dc.contributor.institutionSchool of Engineering and Advanced Technology, Massey University, Palmerston North, New Zealanden
kaust.authorGooneratne, Chinthaka Pasanen
kaust.authorKosel, Jürgenen
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