ncRNA-class Web Tool: Non-coding RNA feature extraction and pre-miRNA classification web tool

Handle URI:
http://hdl.handle.net/10754/564502
Title:
ncRNA-class Web Tool: Non-coding RNA feature extraction and pre-miRNA classification web tool
Authors:
Kleftogiannis, Dimitrios A. ( 0000-0003-1086-821X ) ; Theofilatos, Konstantinos A.; Papadimitriou, Stergios; Tsakalidis, Athanasios K.; Likothanassis, Spiridon D.; Mavroudi, Seferina P.
Abstract:
Until recently, it was commonly accepted that most genetic information is transacted by proteins. Recent evidence suggests that the majority of the genomes of mammals and other complex organisms are in fact transcribed into non-coding RNAs (ncRNAs), many of which are alternatively spliced and/or processed into smaller products. Non coding RNA genes analysis requires the calculation of several sequential, thermodynamical and structural features. Many independent tools have already been developed for the efficient calculation of such features but to the best of our knowledge there does not exist any integrative approach for this task. The most significant amount of existing work is related to the miRNA class of non-coding RNAs. MicroRNAs (miRNAs) are small non-coding RNAs that play a significant role in gene regulation and their prediction is a challenging bioinformatics problem. Non-coding RNA feature extraction and pre-miRNA classification Web Tool (ncRNA-class Web Tool) is a publicly available web tool ( http://150.140.142.24:82/Default.aspx ) which provides a user friendly and efficient environment for the effective calculation of a set of 58 sequential, thermodynamical and structural features of non-coding RNAs, plus a tool for the accurate prediction of miRNAs. © 2012 IFIP International Federation for Information Processing.
KAUST Department:
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division; Computer Science Program
Publisher:
Springer Science + Business Media
Journal:
IFIP Advances in Information and Communication Technology
Conference/Event name:
8th International Workshop on Artificial Intelligence Applications and Innovations, AIAI 2012: AIAB, AIeIA, CISE, COPA, IIVC, ISQL, MHDW, and WADTMB
Issue Date:
2012
DOI:
10.1007/978-3-642-33412-2_65
Type:
Conference Paper
ISSN:
18684238
ISBN:
9783642334115
Appears in Collections:
Conference Papers; Computer Science Program; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorKleftogiannis, Dimitrios A.en
dc.contributor.authorTheofilatos, Konstantinos A.en
dc.contributor.authorPapadimitriou, Stergiosen
dc.contributor.authorTsakalidis, Athanasios K.en
dc.contributor.authorLikothanassis, Spiridon D.en
dc.contributor.authorMavroudi, Seferina P.en
dc.date.accessioned2015-08-04T07:02:38Zen
dc.date.available2015-08-04T07:02:38Zen
dc.date.issued2012en
dc.identifier.isbn9783642334115en
dc.identifier.issn18684238en
dc.identifier.doi10.1007/978-3-642-33412-2_65en
dc.identifier.urihttp://hdl.handle.net/10754/564502en
dc.description.abstractUntil recently, it was commonly accepted that most genetic information is transacted by proteins. Recent evidence suggests that the majority of the genomes of mammals and other complex organisms are in fact transcribed into non-coding RNAs (ncRNAs), many of which are alternatively spliced and/or processed into smaller products. Non coding RNA genes analysis requires the calculation of several sequential, thermodynamical and structural features. Many independent tools have already been developed for the efficient calculation of such features but to the best of our knowledge there does not exist any integrative approach for this task. The most significant amount of existing work is related to the miRNA class of non-coding RNAs. MicroRNAs (miRNAs) are small non-coding RNAs that play a significant role in gene regulation and their prediction is a challenging bioinformatics problem. Non-coding RNA feature extraction and pre-miRNA classification Web Tool (ncRNA-class Web Tool) is a publicly available web tool ( http://150.140.142.24:82/Default.aspx ) which provides a user friendly and efficient environment for the effective calculation of a set of 58 sequential, thermodynamical and structural features of non-coding RNAs, plus a tool for the accurate prediction of miRNAs. © 2012 IFIP International Federation for Information Processing.en
dc.publisherSpringer Science + Business Mediaen
dc.subjectfeature calculationen
dc.subjectmiRNAen
dc.subjectmiRNA predictionen
dc.subjectncRNAsen
dc.subjectweb toolen
dc.titlencRNA-class Web Tool: Non-coding RNA feature extraction and pre-miRNA classification web toolen
dc.typeConference Paperen
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Divisionen
dc.contributor.departmentComputer Science Programen
dc.identifier.journalIFIP Advances in Information and Communication Technologyen
dc.conference.date27 September 2012 through 30 September 2012en
dc.conference.name8th International Workshop on Artificial Intelligence Applications and Innovations, AIAI 2012: AIAB, AIeIA, CISE, COPA, IIVC, ISQL, MHDW, and WADTMBen
dc.conference.locationHalkidikien
dc.contributor.institutionDepartment of Computer Engineering and Informatics, University of Patras, Greeceen
dc.contributor.institutionDepartment of Social Work, School of Sciences of Health and Care, Technological Educational Institute of Patras, Greeceen
dc.contributor.institutionDepartment of Information Management, Technological Institute of Kavala, Greeceen
kaust.authorKleftogiannis, Dimitrios A.en
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