A micro-pillar array to trap magnetic beads in microfluidic systems

Handle URI:
http://hdl.handle.net/10754/564433
Title:
A micro-pillar array to trap magnetic beads in microfluidic systems
Authors:
Gooneratne, Chinthaka Pasan; Kosel, Jürgen ( 0000-0002-8998-8275 )
Abstract:
A micro-pillar array (MPA) is proposed in this paper to trap and separate magnetic beads (MBs) in microfluidic systems. MBs are used in many biomedical applications due to being compatible in dimension to biomolecules, the large surface area available to attach biomolecules, and the fact that they can be controlled by a magnetic field. Trapping and separating these labeled biomolecules is an important step toward achieving reliable and accurate quantification for disease diagnostics. Nickel Iron (Ni50Fe 50) micro-pillars were fabricated on a Silicon (Si) substrate by standard microfabrication techniques. Experimental results showed that MBs could be trapped on the MPA at the single bead level and separated from other non-target particles. This principle can easily be extended to trap and separate target biomolecules in heterogeneous biological samples. © 2012 IEEE.
KAUST Department:
Physical Sciences and Engineering (PSE) Division; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division; Electrical Engineering Program; Sensing, Magnetism and Microsystems Lab
Publisher:
Institute of Electrical and Electronics Engineers (IEEE)
Journal:
2012 Sixth International Conference on Sensing Technology (ICST)
Conference/Event name:
2012 6th International Conference on Sensing Technology, ICST 2012
Issue Date:
Dec-2012
DOI:
10.1109/ICSensT.2012.6461798
Type:
Conference Paper
ISSN:
21568065
ISBN:
9781467322485
Appears in Collections:
Conference Papers; Physical Sciences and Engineering (PSE) Division; Electrical Engineering Program; Sensing, Magnetism and Microsystems Lab; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorGooneratne, Chinthaka Pasanen
dc.contributor.authorKosel, Jürgenen
dc.date.accessioned2015-08-04T07:10:17Zen
dc.date.available2015-08-04T07:10:17Zen
dc.date.issued2012-12en
dc.identifier.isbn9781467322485en
dc.identifier.issn21568065en
dc.identifier.doi10.1109/ICSensT.2012.6461798en
dc.identifier.urihttp://hdl.handle.net/10754/564433en
dc.description.abstractA micro-pillar array (MPA) is proposed in this paper to trap and separate magnetic beads (MBs) in microfluidic systems. MBs are used in many biomedical applications due to being compatible in dimension to biomolecules, the large surface area available to attach biomolecules, and the fact that they can be controlled by a magnetic field. Trapping and separating these labeled biomolecules is an important step toward achieving reliable and accurate quantification for disease diagnostics. Nickel Iron (Ni50Fe 50) micro-pillars were fabricated on a Silicon (Si) substrate by standard microfabrication techniques. Experimental results showed that MBs could be trapped on the MPA at the single bead level and separated from other non-target particles. This principle can easily be extended to trap and separate target biomolecules in heterogeneous biological samples. © 2012 IEEE.en
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)en
dc.subjectmagnetic beadsen
dc.subjectmagnetic forceen
dc.subjectmicro-pillaren
dc.subjectmicrofluidicsen
dc.titleA micro-pillar array to trap magnetic beads in microfluidic systemsen
dc.typeConference Paperen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Divisionen
dc.contributor.departmentElectrical Engineering Programen
dc.contributor.departmentSensing, Magnetism and Microsystems Laben
dc.identifier.journal2012 Sixth International Conference on Sensing Technology (ICST)en
dc.conference.date18 December 2012 through 21 December 2012en
dc.conference.name2012 6th International Conference on Sensing Technology, ICST 2012en
dc.conference.locationKolkataen
kaust.authorGooneratne, Chinthaka Pasanen
kaust.authorKosel, Jürgenen
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