Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces

Handle URI:
http://hdl.handle.net/10754/563522
Title:
Raman spectroscopy for detection of stretched DNAs on superhydrophobic surfaces
Authors:
Marini, Monica ( 0000-0001-8182-5239 ) ; Das, Gobind ( 0000-0003-0942-681X ) ; La Rocca, Rosanna; Gentile, Francesco T.; Limongi, Tania; Santoriello, Stefania; Scarpellini, Alice; Di Fabrizio, Enzo M. ( 0000-0001-5886-4678 )
Abstract:
A novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field. © 2014 Elsevier B.V. All rights reserved.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division; Physical Sciences and Engineering (PSE) Division; Materials Science and Engineering Program
Publisher:
Elsevier BV
Journal:
Microelectronic Engineering
Issue Date:
May-2014
DOI:
10.1016/j.mee.2014.04.008
Type:
Article
ISSN:
01679317
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; Materials Science and Engineering Program; Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorMarini, Monicaen
dc.contributor.authorDas, Gobinden
dc.contributor.authorLa Rocca, Rosannaen
dc.contributor.authorGentile, Francesco T.en
dc.contributor.authorLimongi, Taniaen
dc.contributor.authorSantoriello, Stefaniaen
dc.contributor.authorScarpellini, Aliceen
dc.contributor.authorDi Fabrizio, Enzo M.en
dc.date.accessioned2015-08-03T11:53:34Zen
dc.date.available2015-08-03T11:53:34Zen
dc.date.issued2014-05en
dc.identifier.issn01679317en
dc.identifier.doi10.1016/j.mee.2014.04.008en
dc.identifier.urihttp://hdl.handle.net/10754/563522en
dc.description.abstractA novel approach for the study of low concentrated DNAs (60 pM) using microRaman spectroscopy is reported. A superhydrophobic substrate with array of microPillars is fabricated over which the sample was drop casted. The substrate concentrates the molecules in a very small area with higher molecular density, enabling to carry out the microRaman measurements. Two different DNAs (single strand and double strand) were used to investigate through Raman technique. A spectral Raman difference was found to distinguish the ssDNA and dsDNAs. The approach can be of interest for a wide variety of applications ranging from biological materials interactions characterization to the biomedical field. © 2014 Elsevier B.V. All rights reserved.en
dc.publisherElsevier BVen
dc.subjectmicroPillarsen
dc.subjectNucleic acidsen
dc.subjectRaman spectroscopyen
dc.subjectSuperhydrophobicityen
dc.subjectSuspendeden
dc.titleRaman spectroscopy for detection of stretched DNAs on superhydrophobic surfacesen
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentMaterials Science and Engineering Programen
dc.identifier.journalMicroelectronic Engineeringen
dc.contributor.institutionDepartment of Nanostructures, Istituto Italiano di Tecnologia, Via Morego, Genova 16163, Italyen
dc.contributor.institutionBIONEM Lab University of Magna Graecia, Viale Europa 88100, Germaneto-Catanzaro, Italyen
dc.contributor.institutionDepartment of Nanochemistry, Istituto Italiano di Tecnologia, Via Morego, Genova 16163, Italyen
kaust.authorMarini, Monicaen
kaust.authorDas, Gobinden
kaust.authorLimongi, Taniaen
kaust.authorDi Fabrizio, Enzo M.en
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