Genome sequence of the tsetse fly (Glossina morsitans ): Vector of African trypanosomiasis

Handle URI:
http://hdl.handle.net/10754/563509
Title:
Genome sequence of the tsetse fly (Glossina morsitans ): Vector of African trypanosomiasis
Authors:
Watanabe, Junichi; Hattori, Masahira; Berriman, Matthew; Lehane, Michael J.; Hall, Neil; Solano, Philippe; Aksoy, Serap; Hide, Winston; Touré, Yéya Tiémoko; Attardo, Geoffrey M.; Darby, Alistair Charles; Toyoda, Atsushi; Hertz-Fowler, Christiane; Larkin, Denis M.; Cotton, James A.; Sanders, Mandy J.; Swain, Martin T.; Quail, Michael A.; Inoue, Noboru; Ravel, Sophie; Taylor, Todd Duane; Srivastava, Tulika P.; Sharma, Vineet Kumar; Warren, Wesley C.; Wilson, Richard K.; Suzuki, Yutaka; Lawson, Daniel; Hughes, Daniel Seth Toney; Megy, Karyn; Masiga, Daniel K.; Mireji, Paul Odhiambo; Hansen, Immo Alex; Van Den Abbeele, Jan; Benoit, Joshua B.; Bourtzis, Kostas; Obiero, George F O; Robertson, Hugh M.; Jones, Jeffery W.; Zhou, Jingjiang; Field, Linda M.; Friedrich, Markus; Nyanjom, Steven R G; Telleria, Erich Loza; Caljon, Guy; Ribeiro, José M. C.; Acosta-Serrano, Alvaro; Ooi, Cherpheng; Rose, Clair; Price, David P.; Haines, Lee Rafuse; Christoffels, Alan G.; Sim, Cheolho; Pham, Daphne Q D; Denlinger, David L.; Geiser, Dawn L.; Omedo, Irene A.; Winzerling, Joy J.; Peyton, Justin T.; Marucha, Kevin K.; Jonas, Mario; Meuti, Megan E.; Rawlings, Neil David; Zhang, Qirui; Macharia, Rosaline Wanjiru; Michalkova, Veronika; Dashti, Zahra Jalali Sefid; Baumann, Aaron A.; Gäde, Gerd; Marco, Heather G.; Caers, Jelle; Schoofs, Liliane; Riehle, Michael A.; Hu, Wanqi; Tu, Zhijian; Tarone, Aaron M.; Malacrida, Anna Rodolfa; Kibet, Caleb K.; Scolari, Francesca; Koekemoer, J. J. O.; Willis, Judith H.; Gomulski, Ludvik M.; Falchetto, Marco; Scott, Maxwell J.; Fu, Shuhua; Sze, Singhoi; Luiz, Thiago; Weiss, Brian L.; Walshe, Deirdre P.; Wang, Jingwen; Wamalwa, Mark; Mwangi, Sarah; Ramphul, Urvashi N.; Snyder, Anna K.; Brelsfoard, Corey L.; Thomas, Gavin H.; Tsiamis, George; Arensburger, Peter; Rio, Rita V M; Macdonald, Sandy J.; Panji, Sumir; Kruger, Adele F.; Benkahla, Alia; Balyeidhusa, Apollo Simon Peter; Msangi, Atway R.; Okoro, Chinyere K.; Stephens, Dawn; Stanley, Eleanor J.; Mpondo, Feziwe; Wamwiri, Florence N.; Mramba, Furaha; Siwo, Geoffrey H.; Githinji, George; Harkins, Gordon William; Murilla, Grace Adira; Lehväslaiho, Heikki; Malele, Imna I.; Auma, Joanna Eseri; Kinyua, Johnson K.; Ouma, Johnson O.; Okedi, Loyce M A; Manga, Lucien; Aslett, Martin A.; Koffi, Mathurin; Gaunt, Michael W.; Makgamathe, Mmule; Mulder, Nicola Jane; Manangwa, Oliver; Abila, Patrick P.; Wincker, Patrick; Gregory, Richard I.; Bateta, Rosemary; Sakate, Ryuichi; Ommeh, Sheila; Lehane, Stella M.; Imanishi, Tadashi; Osamor, Victor Chukwudi; Kawahara, Yoshihiro
Abstract:
Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous reproduction, and lactation. Here, we describe the sequence and annotation of the 366-megabase Glossina morsitans morsitans genome. Analysis of the genome and the 12,308 predicted protein-encoding genes led to multiple discoveries, including chromosomal integrations of bacterial (Wolbachia) genome sequences, a family of lactation-specific proteins, reduced complement of host pathogen recognition proteins, and reduced olfaction/chemosensory associated genes. These genome data provide a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division
Publisher:
American Association for the Advancement of Science (AAAS)
Journal:
Science
Issue Date:
24-Apr-2014
DOI:
10.1126/science.1249656
PubMed ID:
24763584
PubMed Central ID:
PMC4077534
Type:
Article
ISSN:
00368075
Sponsors:
The public release and future updates of the genome sequence and associated information are hosted at VectorBase (www.vectorbase.org). The genome sequence can also be found at GenBank under the accession no. CCAG010000000. The Glossina morsitans genome project was funded by the Wellcome Trust (grants 085775/Z/08/Z and 098051) and World Health Organization (WHO) Special Programme for Research and Training in Tropical Diseases (TDR) (project no. A90088) and the Ambrose Monell Foundation. Authors also acknowledge support by the Food and Agriculture Organization/International Atomic Energy Agency Coordinated Research Program "Improving SIT for Tsetse Flies through Research on their Symbionts," the European Union Cooperation in Science and Technology (COST) Action FA0701 "Arthropod Symbiosis: From Fundamental Studies to Pest and Disease Management," and a grant-in-aid for Scientific Research on Priority Areas "Comprehensive Genomics" from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (to M. H.). BAC libraries were generated through National Institute of Allergy and Infectious Diseases resources, and sequencing was supported by RIKEN Japan. We thank the staff in the library construction, sequence production, and informatics support groups at the Wellcome Trust Sanger Institute.
Additional Links:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077534
Appears in Collections:
Articles; Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorWatanabe, Junichien
dc.contributor.authorHattori, Masahiraen
dc.contributor.authorBerriman, Matthewen
dc.contributor.authorLehane, Michael J.en
dc.contributor.authorHall, Neilen
dc.contributor.authorSolano, Philippeen
dc.contributor.authorAksoy, Serapen
dc.contributor.authorHide, Winstonen
dc.contributor.authorTouré, Yéya Tiémokoen
dc.contributor.authorAttardo, Geoffrey M.en
dc.contributor.authorDarby, Alistair Charlesen
dc.contributor.authorToyoda, Atsushien
dc.contributor.authorHertz-Fowler, Christianeen
dc.contributor.authorLarkin, Denis M.en
dc.contributor.authorCotton, James A.en
dc.contributor.authorSanders, Mandy J.en
dc.contributor.authorSwain, Martin T.en
dc.contributor.authorQuail, Michael A.en
dc.contributor.authorInoue, Noboruen
dc.contributor.authorRavel, Sophieen
dc.contributor.authorTaylor, Todd Duaneen
dc.contributor.authorSrivastava, Tulika P.en
dc.contributor.authorSharma, Vineet Kumaren
dc.contributor.authorWarren, Wesley C.en
dc.contributor.authorWilson, Richard K.en
dc.contributor.authorSuzuki, Yutakaen
dc.contributor.authorLawson, Danielen
dc.contributor.authorHughes, Daniel Seth Toneyen
dc.contributor.authorMegy, Karynen
dc.contributor.authorMasiga, Daniel K.en
dc.contributor.authorMireji, Paul Odhiamboen
dc.contributor.authorHansen, Immo Alexen
dc.contributor.authorVan Den Abbeele, Janen
dc.contributor.authorBenoit, Joshua B.en
dc.contributor.authorBourtzis, Kostasen
dc.contributor.authorObiero, George F Oen
dc.contributor.authorRobertson, Hugh M.en
dc.contributor.authorJones, Jeffery W.en
dc.contributor.authorZhou, Jingjiangen
dc.contributor.authorField, Linda M.en
dc.contributor.authorFriedrich, Markusen
dc.contributor.authorNyanjom, Steven R Gen
dc.contributor.authorTelleria, Erich Lozaen
dc.contributor.authorCaljon, Guyen
dc.contributor.authorRibeiro, José M. C.en
dc.contributor.authorAcosta-Serrano, Alvaroen
dc.contributor.authorOoi, Cherphengen
dc.contributor.authorRose, Clairen
dc.contributor.authorPrice, David P.en
dc.contributor.authorHaines, Lee Rafuseen
dc.contributor.authorChristoffels, Alan G.en
dc.contributor.authorSim, Cheolhoen
dc.contributor.authorPham, Daphne Q Den
dc.contributor.authorDenlinger, David L.en
dc.contributor.authorGeiser, Dawn L.en
dc.contributor.authorOmedo, Irene A.en
dc.contributor.authorWinzerling, Joy J.en
dc.contributor.authorPeyton, Justin T.en
dc.contributor.authorMarucha, Kevin K.en
dc.contributor.authorJonas, Marioen
dc.contributor.authorMeuti, Megan E.en
dc.contributor.authorRawlings, Neil Daviden
dc.contributor.authorZhang, Qiruien
dc.contributor.authorMacharia, Rosaline Wanjiruen
dc.contributor.authorMichalkova, Veronikaen
dc.contributor.authorDashti, Zahra Jalali Sefiden
dc.contributor.authorBaumann, Aaron A.en
dc.contributor.authorGäde, Gerden
dc.contributor.authorMarco, Heather G.en
dc.contributor.authorCaers, Jelleen
dc.contributor.authorSchoofs, Lilianeen
dc.contributor.authorRiehle, Michael A.en
dc.contributor.authorHu, Wanqien
dc.contributor.authorTu, Zhijianen
dc.contributor.authorTarone, Aaron M.en
dc.contributor.authorMalacrida, Anna Rodolfaen
dc.contributor.authorKibet, Caleb K.en
dc.contributor.authorScolari, Francescaen
dc.contributor.authorKoekemoer, J. J. O.en
dc.contributor.authorWillis, Judith H.en
dc.contributor.authorGomulski, Ludvik M.en
dc.contributor.authorFalchetto, Marcoen
dc.contributor.authorScott, Maxwell J.en
dc.contributor.authorFu, Shuhuaen
dc.contributor.authorSze, Singhoien
dc.contributor.authorLuiz, Thiagoen
dc.contributor.authorWeiss, Brian L.en
dc.contributor.authorWalshe, Deirdre P.en
dc.contributor.authorWang, Jingwenen
dc.contributor.authorWamalwa, Marken
dc.contributor.authorMwangi, Sarahen
dc.contributor.authorRamphul, Urvashi N.en
dc.contributor.authorSnyder, Anna K.en
dc.contributor.authorBrelsfoard, Corey L.en
dc.contributor.authorThomas, Gavin H.en
dc.contributor.authorTsiamis, Georgeen
dc.contributor.authorArensburger, Peteren
dc.contributor.authorRio, Rita V Men
dc.contributor.authorMacdonald, Sandy J.en
dc.contributor.authorPanji, Sumiren
dc.contributor.authorKruger, Adele F.en
dc.contributor.authorBenkahla, Aliaen
dc.contributor.authorBalyeidhusa, Apollo Simon Peteren
dc.contributor.authorMsangi, Atway R.en
dc.contributor.authorOkoro, Chinyere K.en
dc.contributor.authorStephens, Dawnen
dc.contributor.authorStanley, Eleanor J.en
dc.contributor.authorMpondo, Feziween
dc.contributor.authorWamwiri, Florence N.en
dc.contributor.authorMramba, Furahaen
dc.contributor.authorSiwo, Geoffrey H.en
dc.contributor.authorGithinji, Georgeen
dc.contributor.authorHarkins, Gordon Williamen
dc.contributor.authorMurilla, Grace Adiraen
dc.contributor.authorLehväslaiho, Heikkien
dc.contributor.authorMalele, Imna I.en
dc.contributor.authorAuma, Joanna Eserien
dc.contributor.authorKinyua, Johnson K.en
dc.contributor.authorOuma, Johnson O.en
dc.contributor.authorOkedi, Loyce M Aen
dc.contributor.authorManga, Lucienen
dc.contributor.authorAslett, Martin A.en
dc.contributor.authorKoffi, Mathurinen
dc.contributor.authorGaunt, Michael W.en
dc.contributor.authorMakgamathe, Mmuleen
dc.contributor.authorMulder, Nicola Janeen
dc.contributor.authorManangwa, Oliveren
dc.contributor.authorAbila, Patrick P.en
dc.contributor.authorWincker, Patricken
dc.contributor.authorGregory, Richard I.en
dc.contributor.authorBateta, Rosemaryen
dc.contributor.authorSakate, Ryuichien
dc.contributor.authorOmmeh, Sheilaen
dc.contributor.authorLehane, Stella M.en
dc.contributor.authorImanishi, Tadashien
dc.contributor.authorOsamor, Victor Chukwudien
dc.contributor.authorKawahara, Yoshihiroen
dc.date.accessioned2015-08-03T11:53:15Zen
dc.date.available2015-08-03T11:53:15Zen
dc.date.issued2014-04-24en
dc.identifier.issn00368075en
dc.identifier.pmid24763584en
dc.identifier.doi10.1126/science.1249656en
dc.identifier.urihttp://hdl.handle.net/10754/563509en
dc.description.abstractTsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous reproduction, and lactation. Here, we describe the sequence and annotation of the 366-megabase Glossina morsitans morsitans genome. Analysis of the genome and the 12,308 predicted protein-encoding genes led to multiple discoveries, including chromosomal integrations of bacterial (Wolbachia) genome sequences, a family of lactation-specific proteins, reduced complement of host pathogen recognition proteins, and reduced olfaction/chemosensory associated genes. These genome data provide a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology.en
dc.description.sponsorshipThe public release and future updates of the genome sequence and associated information are hosted at VectorBase (www.vectorbase.org). The genome sequence can also be found at GenBank under the accession no. CCAG010000000. The Glossina morsitans genome project was funded by the Wellcome Trust (grants 085775/Z/08/Z and 098051) and World Health Organization (WHO) Special Programme for Research and Training in Tropical Diseases (TDR) (project no. A90088) and the Ambrose Monell Foundation. Authors also acknowledge support by the Food and Agriculture Organization/International Atomic Energy Agency Coordinated Research Program "Improving SIT for Tsetse Flies through Research on their Symbionts," the European Union Cooperation in Science and Technology (COST) Action FA0701 "Arthropod Symbiosis: From Fundamental Studies to Pest and Disease Management," and a grant-in-aid for Scientific Research on Priority Areas "Comprehensive Genomics" from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (to M. H.). BAC libraries were generated through National Institute of Allergy and Infectious Diseases resources, and sequencing was supported by RIKEN Japan. We thank the staff in the library construction, sequence production, and informatics support groups at the Wellcome Trust Sanger Institute.en
dc.publisherAmerican Association for the Advancement of Science (AAAS)en
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077534en
dc.titleGenome sequence of the tsetse fly (Glossina morsitans ): Vector of African trypanosomiasisen
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.identifier.journalScienceen
dc.identifier.pmcidPMC4077534en
dc.contributor.institutionBiological Sciences Department, California State Polytechnic University Pomona, 3801 West Temple Avenue, Pomona, CA 91768, United Statesen
dc.contributor.institutionBiomedical Sciences Research Center, Alexander Fleming Biomedical Sciences Research Center, 34 Fleming Street, Vari, 16672, Greeceen
dc.contributor.institutionCEA, Genoscope, 2 Rue Gaston Crémieux, Evry Cedex, 91507, Franceen
dc.contributor.institutionCenter for Biotechnology and Bioinformatics, University of Nairobi, Post Office Box 30197-00100, Nairobi, Kenyaen
dc.contributor.institutionCenter for Omics and Bioinformatics, Department of Computational Biology, University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8561, Japanen
dc.contributor.institutionComparative Genomics Laboratory, National Institute of Genetics, 411-8540 Yata 1111, Mishima, Shizuoka, 411-8540, Japanen
dc.contributor.institutionComputational Biology Group, IIDMM, University of Cape Town Faculty of Health Sciences, Cape Town, 7925, South Africaen
dc.contributor.institutionDepartment of Biochemistry and Biophysics, Texas A and M University, 328B TAMU, College Station, TX 77843, United Statesen
dc.contributor.institutionDepartment of Biochemistry and Molecular Biology, Egerton University, Post Office Box 536, Njoro, Kenyaen
dc.contributor.institutionDepartment of Biochemistry, Jomo Kenyatta University of Agriculture and Technology (JKUAT), Post Office Box 62000-00200, Nairobi, Kenyaen
dc.contributor.institutionDepartment of Biochemistry, Virginia Polytechnic Institute and State University, 309 Fralin Hall, Blacksburg, VA 24061, United Statesen
dc.contributor.institutionDepartment of Biological Chemistry and Crop Protection, Rothamsted Research, West Common, Harpenden, Herts, AL5 2JQ, United Kingdomen
dc.contributor.institutionDepartment of Biological Sciences, McMicken College of Arts and Sciences, University of Cincinnati, Cincinnati, OH 45221, United Statesen
dc.contributor.institutionDepartment of Biological Sciences, University of Cape Town, Private Bag, Rondebosch, ZA-7700, South Africaen
dc.contributor.institutionDepartment of Biological Sciences, University of Wisconsin-Parkside, 900 Wood Road, Kenosha, WI 53144, United Statesen
dc.contributor.institutionDepartment of Biological Sciences, Wayne State University, 5047 Gullen Mall, Detroit, MI 48202, United Statesen
dc.contributor.institutionDepartment of Biology and Biotechnology, University of Pavia, Via Ferrata 9, Pavia, 27100, Italyen
dc.contributor.institutionDepartment of Biology, Baylor University, Waco, TX 76798, United Statesen
dc.contributor.institutionDepartment of Biology, KU Leuven, Naamsestraat 59, Leuven, B-3000, Belgiumen
dc.contributor.institutionDepartment of Biology, New Mexico State University, Foster Hall 263, Las Cruces, NM 88003, United Statesen
dc.contributor.institutionDepartment of Biology, University of York, Wentworth Way, York, Y010 5DD, United Kingdomen
dc.contributor.institutionDepartment of Biology, West Virginia University, 5106 LSB, 53 Campus Drive, Morgantown, WV, United Statesen
dc.contributor.institutionDepartment of Biomedical Sciences, Institute of Tropical Medicine Antwerp, Nationalestraat 155, Antwerp, B-2000, Belgiumen
dc.contributor.institutionDepartment of Cellular Biology, University of Georgia, 302 Biological Sciences Building, Athens, GA 30602, United Statesen
dc.contributor.institutionDepartment of Clinical Research, KEMRI-Wellcome Trust Programme, CGMRC, Post Office Box 230-80108, Kilifi, Kenyaen
dc.contributor.institutionDepartment of Computer and Information Sciences, College of Science and Technology, Covenant University, P.M.B. 1023, Ota, Ogun State, Nigeriaen
dc.contributor.institutionDepartment of Computer Science and Engineering, Texas A and M University, HRBB 328B TAMU, College Station, TX 77843, United Statesen
dc.contributor.institutionDepartment of Entomology, North Carolina State University, Campus Box 7613, Raleigh, NC 27695-7613, United Statesen
dc.contributor.institutionDepartment of Entomology, Texas A and M University, 2475 TAMU, College Station, TX 77843, United Statesen
dc.contributor.institutionDepartment of Entomology, Ohio State University, 400 Aronoff Laboratory, 318 West 12th Avenue, Columbus, OH 43210, United Statesen
dc.contributor.institutionDepartment of Entomology, University of Arizona, Forbes 410, 1140 East South Campus Drive, Tucson, AZ 85721, United Statesen
dc.contributor.institutionDepartment of Entomology, University of Illinois at Urbana-Champaign, 505 South Goodwin Avenue, Urbana, IL 61801, United Statesen
dc.contributor.institutionInsect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Vienna, 1220, Austriaen
dc.contributor.institutionDepartment of Environmental and Natural Resources Management, University of Patras, 2 Seferi Street, Agrinio, 30100, Greeceen
dc.contributor.institutionDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, 60 College Street, New Haven, CT 06520, United Statesen
dc.contributor.institutionDepartment of Evolution, Ecology, and Organismal Biology, Ohio State University, 300 Aronoff Laboratory, 318 West 12th Avenue, Columbus, OH 43210, United Statesen
dc.contributor.institutionDepartment of Natural Sciences, St. Catharine College, 2735 Bardstown Road, St. Catharine, KY 40061, United Statesen
dc.contributor.institutionDepartment of Nutritional Sciences, University of Arizona, College of Agriculture and Life Sciences, Post Office Box 210036, Tucson, AZ 85721-0036, United Statesen
dc.contributor.institutionDepartment of Nutritional Sciences, University of Arizona, Shantz 405, 1177 East 4th Street, Tucson, AZ 85721-0038, United Statesen
dc.contributor.institutionDepartment of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, United Kingdomen
dc.contributor.institutionDepartment of Parasitology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, United Kingdomen
dc.contributor.institutionDepartment of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, United Kingdomen
dc.contributor.institutionEntomology Section, Onderstepoort Veterinary Institute, Private Bag X5, Onderstepoort, 110, South Africaen
dc.contributor.institutionEck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, United Statesen
dc.contributor.institutionDepartment of Veterinary Tropical Diseases, University of Pretoria, Private Bag X04, Onderstepoort, 110, South Africaen
dc.contributor.institutionEuropean Molecular Biology Laboratories, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, Cambridgeshire, CB10 1SA, United Kingdomen
dc.contributor.institutionGroup of Bioinformatics and Modeling, Laboratory of Medical Parasitology, Biotechnology, and Biomolecules, Institut Pasteur de Tunis, 13, Place Pasteur, Belvédère, Tunis, 1002, Tunisiaen
dc.contributor.institutionInstitut de Recherche Pour le Développement (IRD), UMR 177 IRD-CIRAD INTERTRYP, CIRDES Bobo-Dioulasso, Burkina Fasoen
dc.contributor.institutionInstitut de Recherche Pour le Développement (IRD), UMR 177 IRD-CIRAD INTERTRYP, LRCT Campus International de Baillarguet, Montpellier, Franceen
dc.contributor.institutionInstitute of Biological, Environmental, and Rural Sciences, University of Aberystwyth, Old College, King Street, Aberystwyth, Ceredigion, SY23 3FG, United Kingdomen
dc.contributor.institutionInstitute of Biotechnology Research, Jomo Kenyatta University of Agriculture and Technology (JKUAT), Post Office Box 62000-00200, Nairobi, Kenyaen
dc.contributor.institutionInstitute of Integrative Biology, University of Liverpool, Crown Street, Liverpool, L69 7ZB, United Kingdomen
dc.contributor.institutionInstitute of Zoology, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava, 845 06, Slovakiaen
dc.contributor.institutionIntegrated Database Team, Biological Information Research Center, National Institute of Advanced Industrial Science and Technology, Aomi 2-4-7, Koto-ku, Tokyo, 135-0064, Japanen
dc.contributor.institutionKenya Agricultural Research Institute, Trypanosomiasis Research Centre, Post Office Box 362, Kikuyu, 902, Kenyaen
dc.contributor.institutionLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, 12735 Twinbrook Parkway, Rockville, MD 20852, United Statesen
dc.contributor.institutionTechnology Innovation Agency, National Genomics Platform, Post Office Box 30603, Mayville, Durban, 4058, South Africaen
dc.contributor.institutionDepartment of Biochemistry and Sports Science, Makerere University, Post Office Box 7062, Kampala, Ugandaen
dc.contributor.institutionBateman Group, EMBL European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, Cambridgeshire, CB10 1SA, United Kingdomen
dc.contributor.institutionMolecular Biology and Bioinformatics Unit, International Center of Insect Physiology and Ecology, Duduville Campus, Kasarani, Post Office Box 30772-00100, Nairobi, Kenyaen
dc.contributor.institutionNational Livestock Resources Research Institute (NaLIRRI), Post Office Box 96, Tororo, Ugandaen
dc.contributor.institutionNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido, 080-8555, Japanen
dc.contributor.institutionParasite Genomics Group, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, Cambridgeshire, CB10 1SA, United Kingdomen
dc.contributor.institutionRiddiford Laboratory, Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, United Statesen
dc.contributor.institutionRIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumiku, Yokohama, Kanagawa, 230-0045, Japanen
dc.contributor.institutionSouth African National Bioinformatics Institute, South African MRC Bioinformatics Unit, University of the Western Cape, Modderdam Road, Bellville 7530, South Africaen
dc.contributor.institutionSpecial Programme for Research and Training in Tropical Diseases (TDR), WHO, Avenue Appia 20, 1211 Geneva 27, Switzerlanden
dc.contributor.institutionGenome Institute, Washington University School of Medicine, St. Louis, MO 63110, United Statesen
dc.contributor.institutionTsetse and Trypanosomiasis Research Institute (TTRI), Majani Mapana, Off Korogwe Road, Tanga, Tanzaniaen
dc.contributor.institutionVector Health International, Post Office Box 15500, Arusha, Tanzaniaen
dc.contributor.institutionWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, Cambridgeshire, CB10 1SA, United Kingdomen
dc.contributor.institutionWHO Regional Office for Africa, WHO, Cité du Djoué, Post Office Box 06, Brazzaville, Congoen
dc.contributor.institutionSchool of Basic Sciences, Indian Institute of Technology, Mandi 175001, Himachal Pradesh, Indiaen
dc.contributor.institutionDepartment of Parasite, Vector, and Human Biology, KEMRI-Wellcome Trust Programme, CGMRC, Post Office Box 230-80108, Kilifi, Kenyaen
dc.contributor.institutionInstitute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japanen
dc.contributor.institutionDepartment of Biochemistry and Biotechnology, Kenyatta University, Post Office Box 43844-00100, Nairobi, Kenyaen
dc.contributor.institutionDepartment of Biological Sciences, Indian Institute of Science Education and Research, Indore Bypass Road, Bhauri District, Bhopal, Madhya Pradesh, 462066, Indiaen
dc.contributor.institutionFaculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabiaen
dc.contributor.institutionDepartment of Biostatistics, Harvard School of Public Health, 655 Huntington Ave., Boston, MA 02461, United Statesen
dc.contributor.institutionBioinformatics Research Unit, Agrogenomics Research Center, National Institute of Agrobiological Sciences, 2-1-2, Kannondai, Tsukuba, Ibaraki 305-8602, Japanen
kaust.authorLehväslaiho, Heikkien
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