Optimized fabrication protocols of microfluidic devices for X-ray analysis

Handle URI:
http://hdl.handle.net/10754/563007
Title:
Optimized fabrication protocols of microfluidic devices for X-ray analysis
Authors:
Catalano, Rossella; Perozziello, Gerardo; Simone, Giuseppina; Candeloro, Patrizio; Gentile, Francesco T.; Coluccio, Maria Laura; Pardeo, Francesca; Burghammer, Manfred C.; Cuda, Giovanni; Riekel, Christian; Di Fabrizio, Enzo M. ( 0000-0001-5886-4678 )
Abstract:
Microfluidics combined with X-ray scattering techniques allows probing conformational changes or assembly processes of biological materials. Our aim was to develop a highly X-ray transparent microfluidic cell for detecting small variations of X-ray scattering involved in such processes. We describe the fabrication of a polyimide microfluidic device based on a simple, reliable and inexpensive lamination process. The implemented microstructured features result in windows with optimized X-ray transmission. The microfluidic device was characterized by X-ray microbeam scattering at the ID13 beamline of the European Synchrotron Radiation Facility. © 2014 Elsevier B.V. All rights reserved.
KAUST Department:
Physical Sciences and Engineering (PSE) Division; Materials Science and Engineering Program
Publisher:
Elsevier BV
Journal:
Microelectronic Engineering
Issue Date:
Jul-2014
DOI:
10.1016/j.mee.2014.04.016
Type:
Article
ISSN:
01679317
Sponsors:
This work was partially supported by the European project EUROMBR (grant agreement n. 608104), the project for Young Researchers financed from the Italian Ministry of Health (CUP J65C13001350001, project n. GR-2010-2311677) and the project FIRB "ReteNazionale di Ricerca sulle Nanoscienze ItalNanoNet" (cod. RBPR05JH2P_010, CUP B41J09000110005) granted to the nanotechnology laboratory of the Department of Experimental Medicine of the University of Catanzaro.
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; Materials Science and Engineering Program

Full metadata record

DC FieldValue Language
dc.contributor.authorCatalano, Rossellaen
dc.contributor.authorPerozziello, Gerardoen
dc.contributor.authorSimone, Giuseppinaen
dc.contributor.authorCandeloro, Patrizioen
dc.contributor.authorGentile, Francesco T.en
dc.contributor.authorColuccio, Maria Lauraen
dc.contributor.authorPardeo, Francescaen
dc.contributor.authorBurghammer, Manfred C.en
dc.contributor.authorCuda, Giovannien
dc.contributor.authorRiekel, Christianen
dc.contributor.authorDi Fabrizio, Enzo M.en
dc.date.accessioned2015-08-03T12:04:02Zen
dc.date.available2015-08-03T12:04:02Zen
dc.date.issued2014-07en
dc.identifier.issn01679317en
dc.identifier.doi10.1016/j.mee.2014.04.016en
dc.identifier.urihttp://hdl.handle.net/10754/563007en
dc.description.abstractMicrofluidics combined with X-ray scattering techniques allows probing conformational changes or assembly processes of biological materials. Our aim was to develop a highly X-ray transparent microfluidic cell for detecting small variations of X-ray scattering involved in such processes. We describe the fabrication of a polyimide microfluidic device based on a simple, reliable and inexpensive lamination process. The implemented microstructured features result in windows with optimized X-ray transmission. The microfluidic device was characterized by X-ray microbeam scattering at the ID13 beamline of the European Synchrotron Radiation Facility. © 2014 Elsevier B.V. All rights reserved.en
dc.description.sponsorshipThis work was partially supported by the European project EUROMBR (grant agreement n. 608104), the project for Young Researchers financed from the Italian Ministry of Health (CUP J65C13001350001, project n. GR-2010-2311677) and the project FIRB "ReteNazionale di Ricerca sulle Nanoscienze ItalNanoNet" (cod. RBPR05JH2P_010, CUP B41J09000110005) granted to the nanotechnology laboratory of the Department of Experimental Medicine of the University of Catanzaro.en
dc.publisherElsevier BVen
dc.subjectLamination processen
dc.subjectPolyimide microfluidic deviceen
dc.subjectX-ray scatteringen
dc.titleOptimized fabrication protocols of microfluidic devices for X-ray analysisen
dc.typeArticleen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentMaterials Science and Engineering Programen
dc.identifier.journalMicroelectronic Engineeringen
dc.contributor.institutionLab. BioNEM, University of Catanzaro, Catanzaro 88100, Italyen
dc.contributor.institutionCRIB, Univerity of Naples (Federico II), Napoli 80125, Italyen
dc.contributor.institutionEuropean Synchrotron Radiation Facility, Grenoble 38100, Franceen
kaust.authorDi Fabrizio, Enzo M.en
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