An air-stable copper reagent for nucleophilic trifluoromethylthiolation of aryl halides

Handle URI:
http://hdl.handle.net/10754/562457
Title:
An air-stable copper reagent for nucleophilic trifluoromethylthiolation of aryl halides
Authors:
Weng, Zhiqiang; He, Weiming; Chen, Chaohuang; Lee, Richmond; Tan, Davin; Lai, Zhiping ( 0000-0001-9555-6009 ) ; Kong, Dedao; Yuan, Yaofeng; Huang, Kuo-Wei ( 0000-0003-1900-2658 )
Abstract:
A series of copper(I) trifluoromethyl thiolate complexes have been synthesized from the reaction of CuF2 with Me3SiCF 3 and S8 (see scheme; Cu red, F green, N blue, S yellow). These air-stable complexes serve as reagents for the efficient conversion of a wide range of aryl halides into the corresponding aryl trifluoromethyl thioethers in excellent yields. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
KAUST Department:
Physical Sciences and Engineering (PSE) Division; Chemical and Biological Engineering Program; Advanced Membranes and Porous Materials Research Center; Chemical Science Program; KAUST Catalysis Center (KCC); HCL
Publisher:
Wiley-Blackwell
Journal:
Angewandte Chemie International Edition
Issue Date:
12-Dec-2012
DOI:
10.1002/anie.201208432
PubMed ID:
23239429
Type:
Article
ISSN:
14337851
Sponsors:
We thank Prof. John Hartwig for useful discussions. The financial support from National Natural Science Foundation of China (21072030) and Fuzhou University (022318) to Z.W. and KAUST to K.-W.H. are acknowledged.
Is Supplemented By:
Weng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900614: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz752f; DOI:10.5517/ccz752f; HANDLE:http://hdl.handle.net/10754/624751; Weng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900613: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz751d; DOI:10.5517/ccz751d; HANDLE:http://hdl.handle.net/10754/624750; Weng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900612: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz750c; DOI:10.5517/ccz750c; HANDLE:http://hdl.handle.net/10754/624749; Weng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900611: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz74z9; DOI:10.5517/ccz74z9; HANDLE:http://hdl.handle.net/10754/624748
Appears in Collections:
Articles; Advanced Membranes and Porous Materials Research Center; Physical Sciences and Engineering (PSE) Division; Chemical Science Program; Chemical and Biological Engineering Program; KAUST Catalysis Center (KCC)

Full metadata record

DC FieldValue Language
dc.contributor.authorWeng, Zhiqiangen
dc.contributor.authorHe, Weimingen
dc.contributor.authorChen, Chaohuangen
dc.contributor.authorLee, Richmonden
dc.contributor.authorTan, Davinen
dc.contributor.authorLai, Zhipingen
dc.contributor.authorKong, Dedaoen
dc.contributor.authorYuan, Yaofengen
dc.contributor.authorHuang, Kuo-Weien
dc.date.accessioned2015-08-03T10:38:53Zen
dc.date.available2015-08-03T10:38:53Zen
dc.date.issued2012-12-12en
dc.identifier.issn14337851en
dc.identifier.pmid23239429en
dc.identifier.doi10.1002/anie.201208432en
dc.identifier.urihttp://hdl.handle.net/10754/562457en
dc.description.abstractA series of copper(I) trifluoromethyl thiolate complexes have been synthesized from the reaction of CuF2 with Me3SiCF 3 and S8 (see scheme; Cu red, F green, N blue, S yellow). These air-stable complexes serve as reagents for the efficient conversion of a wide range of aryl halides into the corresponding aryl trifluoromethyl thioethers in excellent yields. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.en
dc.description.sponsorshipWe thank Prof. John Hartwig for useful discussions. The financial support from National Natural Science Foundation of China (21072030) and Fuzhou University (022318) to Z.W. and KAUST to K.-W.H. are acknowledged.en
dc.publisherWiley-Blackwellen
dc.subjectC-S bondsen
dc.subjectcopperen
dc.subjectcross-couplingen
dc.subjecttrifluoromethylthiolationen
dc.titleAn air-stable copper reagent for nucleophilic trifluoromethylthiolation of aryl halidesen
dc.typeArticleen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentChemical and Biological Engineering Programen
dc.contributor.departmentAdvanced Membranes and Porous Materials Research Centeren
dc.contributor.departmentChemical Science Programen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.contributor.departmentHCLen
dc.identifier.journalAngewandte Chemie International Editionen
dc.contributor.institutionDepartment of Chemistry, Fujian Provincial Key Laboratory of Photocatalysis, Fuzhou University, Fuzhou 350002, Chinaen
kaust.authorLee, Richmonden
kaust.authorTan, Davinen
kaust.authorLai, Zhipingen
kaust.authorHuang, Kuo-Weien
dc.relation.isSupplementedByWeng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900614: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz752fen
dc.relation.isSupplementedByDOI:10.5517/ccz752fen
dc.relation.isSupplementedByHANDLE:http://hdl.handle.net/10754/624751en
dc.relation.isSupplementedByWeng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900613: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz751den
dc.relation.isSupplementedByDOI:10.5517/ccz751den
dc.relation.isSupplementedByHANDLE:http://hdl.handle.net/10754/624750en
dc.relation.isSupplementedByWeng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900612: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz750cen
dc.relation.isSupplementedByDOI:10.5517/ccz750cen
dc.relation.isSupplementedByHANDLE:http://hdl.handle.net/10754/624749en
dc.relation.isSupplementedByWeng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900611: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz74z9en
dc.relation.isSupplementedByDOI:10.5517/ccz74z9en
dc.relation.isSupplementedByHANDLE:http://hdl.handle.net/10754/624748en

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