Synthesis of trifluoromethylated acetylenes via copper-catalyzed trifluoromethylation of alkynyltrifluoroborates

Handle URI:
http://hdl.handle.net/10754/562444
Title:
Synthesis of trifluoromethylated acetylenes via copper-catalyzed trifluoromethylation of alkynyltrifluoroborates
Authors:
Zheng, Huidong; Huang, Yuanyuan; Wang, Zhiwei; Li, Huaifeng ( 0000-0001-9661-803X ) ; Huang, Kuo-Wei ( 0000-0003-1900-2658 ) ; Yuan, Yaofeng; Weng, Zhiqiang
Abstract:
A new method for the synthesis of trifluoromethylated acetylenes is developed which involves the copper-catalyzed trifluoromethylation of alkynyltrifluoroborates with an electrophilic trifluoromethylating reagent. This method offers significant advantages such as efficiency and mild and base-free reaction conditions. A plausible mechanism is proposed. © 2012 Elsevier Ltd. All rights reserved.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division; KAUST Catalysis Center (KCC); Chemical Science Program; Physical Sciences and Engineering (PSE) Division; HCL
Publisher:
Elsevier BV
Journal:
Tetrahedron Letters
Issue Date:
Dec-2012
DOI:
10.1016/j.tetlet.2012.09.083
Type:
Article
ISSN:
00404039
Sponsors:
We acknowledge financial support from the National Natural Science Foundation of China (21072030) and the Fuzhou University (022318) to Z.W. and the King Abdullah University of Science and Technology to K.-W.H.
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; Chemical Science Program; KAUST Catalysis Center (KCC); Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorZheng, Huidongen
dc.contributor.authorHuang, Yuanyuanen
dc.contributor.authorWang, Zhiweien
dc.contributor.authorLi, Huaifengen
dc.contributor.authorHuang, Kuo-Weien
dc.contributor.authorYuan, Yaofengen
dc.contributor.authorWeng, Zhiqiangen
dc.date.accessioned2015-08-03T10:38:24Zen
dc.date.available2015-08-03T10:38:24Zen
dc.date.issued2012-12en
dc.identifier.issn00404039en
dc.identifier.doi10.1016/j.tetlet.2012.09.083en
dc.identifier.urihttp://hdl.handle.net/10754/562444en
dc.description.abstractA new method for the synthesis of trifluoromethylated acetylenes is developed which involves the copper-catalyzed trifluoromethylation of alkynyltrifluoroborates with an electrophilic trifluoromethylating reagent. This method offers significant advantages such as efficiency and mild and base-free reaction conditions. A plausible mechanism is proposed. © 2012 Elsevier Ltd. All rights reserved.en
dc.description.sponsorshipWe acknowledge financial support from the National Natural Science Foundation of China (21072030) and the Fuzhou University (022318) to Z.W. and the King Abdullah University of Science and Technology to K.-W.H.en
dc.publisherElsevier BVen
dc.subjectAlkynyltrifluoroboratesen
dc.subjectCopper catalysisen
dc.subjectTrifluoromethylated acetylenesen
dc.subjectTrifluoromethylationen
dc.titleSynthesis of trifluoromethylated acetylenes via copper-catalyzed trifluoromethylation of alkynyltrifluoroboratesen
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.contributor.departmentChemical Science Programen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentHCLen
dc.identifier.journalTetrahedron Lettersen
dc.contributor.institutionCollege of Chemistry and Chemical Engineering, Fuzhou University, Fujian 350108, Chinaen
kaust.authorLi, Huaifengen
kaust.authorHuang, Kuo-Weien
All Items in KAUST are protected by copyright, with all rights reserved, unless otherwise indicated.