Mild copper-catalyzed trifluoromethylation of terminal alkynes using an electrophilic trifluoromethylating reagent

Handle URI:
http://hdl.handle.net/10754/562120
Title:
Mild copper-catalyzed trifluoromethylation of terminal alkynes using an electrophilic trifluoromethylating reagent
Authors:
Weng, Zhiqiang; Li, Huaifeng ( 0000-0001-9661-803X ) ; He, Weiming; Yao, Liangfeng; Tan, Jianwei; Chen, Jinfa; Yuan, Yaofeng; Huang, Kuo-Wei ( 0000-0003-1900-2658 )
Abstract:
A catalytic process for trifluoromethylation of terminal alkynes with Togni's reagent has been developed, affording trifluoromethylated acetylenes in good to excellent yields. The reaction is conducted at room temperature and exhibits tolerance to a range of functional groups. © 2012 Elsevier Ltd. All rights reserved.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division; KAUST Catalysis Center (KCC); Chemical Science Program; Physical Sciences and Engineering (PSE) Division; HCL
Publisher:
Elsevier
Journal:
Tetrahedron
Issue Date:
Mar-2012
DOI:
10.1016/j.tet.2011.12.085
Type:
Article
ISSN:
00404020
Sponsors:
We acknowledge the financial support from King Abdullah University of Science and Technology to K.-W.H. and from National Natural Science Foundation of China (21072030) and Fuzhou University (022318) to Z.W.
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; Chemical Science Program; KAUST Catalysis Center (KCC); Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorWeng, Zhiqiangen
dc.contributor.authorLi, Huaifengen
dc.contributor.authorHe, Weimingen
dc.contributor.authorYao, Liangfengen
dc.contributor.authorTan, Jianweien
dc.contributor.authorChen, Jinfaen
dc.contributor.authorYuan, Yaofengen
dc.contributor.authorHuang, Kuo-Weien
dc.date.accessioned2015-08-03T09:45:16Zen
dc.date.available2015-08-03T09:45:16Zen
dc.date.issued2012-03en
dc.identifier.issn00404020en
dc.identifier.doi10.1016/j.tet.2011.12.085en
dc.identifier.urihttp://hdl.handle.net/10754/562120en
dc.description.abstractA catalytic process for trifluoromethylation of terminal alkynes with Togni's reagent has been developed, affording trifluoromethylated acetylenes in good to excellent yields. The reaction is conducted at room temperature and exhibits tolerance to a range of functional groups. © 2012 Elsevier Ltd. All rights reserved.en
dc.description.sponsorshipWe acknowledge the financial support from King Abdullah University of Science and Technology to K.-W.H. and from National Natural Science Foundation of China (21072030) and Fuzhou University (022318) to Z.W.en
dc.publisherElsevieren
dc.subjectCopper catalysten
dc.subjectTerminal alkyneen
dc.subjectTrifluoromethylation reactionen
dc.titleMild copper-catalyzed trifluoromethylation of terminal alkynes using an electrophilic trifluoromethylating reagenten
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.contributor.departmentChemical Science Programen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentHCLen
dc.identifier.journalTetrahedronen
dc.contributor.institutionDepartment of Chemistry, Fuzhou University, Fujian 350108, Chinaen
kaust.authorLi, Huaifengen
kaust.authorYao, Liangfengen
kaust.authorHuang, Kuo-Weien
All Items in KAUST are protected by copyright, with all rights reserved, unless otherwise indicated.