Role of miRNAs and siRNAs in biotic and abiotic stress responses of plants

Handle URI:
http://hdl.handle.net/10754/562079
Title:
Role of miRNAs and siRNAs in biotic and abiotic stress responses of plants
Authors:
Khraiwesh, Basel; Zhu, Jian-Kang; Zhu, Jianhua
Abstract:
Small, non-coding RNAs are a distinct class of regulatory RNAs in plants and animals that control a variety of biological processes. In plants, several classes of small RNAs with specific sizes and dedicated functions have evolved through a series of pathways. The major classes of small RNAs include microRNAs (miRNAs) and small interfering RNAs (siRNAs), which differ in their biogenesis. miRNAs control the expression of cognate target genes by binding to reverse complementary sequences, resulting in cleavage or translational inhibition of the target RNAs. siRNAs have a similar structure, function, and biogenesis as miRNAs but are derived from long double-stranded RNAs and can often direct DNA methylation at target sequences. Besides their roles in growth and development and maintenance of genome integrity, small RNAs are also important components in plant stress responses. One way in which plants respond to environmental stress is by modifying their gene expression through the activity of small RNAs. Thus, understanding how small RNAs regulate gene expression will enable researchers to explore the role of small RNAs in biotic and abiotic stress responses. This review focuses on the regulatory roles of plant small RNAs in the adaptive response to stresses. This article is part of a Special Issue entitled: Plant gene regulation in response to abiotic stress. © 2011 Elsevier B.V.
KAUST Department:
Center for Desert Agriculture
Publisher:
Elsevier
Journal:
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms
Issue Date:
Feb-2012
DOI:
10.1016/j.bbagrm.2011.05.001
PubMed ID:
21605713
PubMed Central ID:
PMC3175014
Type:
Article
ISSN:
18749399
Sponsors:
This work was supported by USDA and NIH grants to J.-K. Zhu and by National Science Foundation grants IOS0919745 and MCB0950242 to J. Zhu.
Additional Links:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175014
Appears in Collections:
Articles; Center for Desert Agriculture

Full metadata record

DC FieldValue Language
dc.contributor.authorKhraiwesh, Baselen
dc.contributor.authorZhu, Jian-Kangen
dc.contributor.authorZhu, Jianhuaen
dc.date.accessioned2015-08-03T09:44:19Zen
dc.date.available2015-08-03T09:44:19Zen
dc.date.issued2012-02en
dc.identifier.issn18749399en
dc.identifier.pmid21605713en
dc.identifier.doi10.1016/j.bbagrm.2011.05.001en
dc.identifier.urihttp://hdl.handle.net/10754/562079en
dc.description.abstractSmall, non-coding RNAs are a distinct class of regulatory RNAs in plants and animals that control a variety of biological processes. In plants, several classes of small RNAs with specific sizes and dedicated functions have evolved through a series of pathways. The major classes of small RNAs include microRNAs (miRNAs) and small interfering RNAs (siRNAs), which differ in their biogenesis. miRNAs control the expression of cognate target genes by binding to reverse complementary sequences, resulting in cleavage or translational inhibition of the target RNAs. siRNAs have a similar structure, function, and biogenesis as miRNAs but are derived from long double-stranded RNAs and can often direct DNA methylation at target sequences. Besides their roles in growth and development and maintenance of genome integrity, small RNAs are also important components in plant stress responses. One way in which plants respond to environmental stress is by modifying their gene expression through the activity of small RNAs. Thus, understanding how small RNAs regulate gene expression will enable researchers to explore the role of small RNAs in biotic and abiotic stress responses. This review focuses on the regulatory roles of plant small RNAs in the adaptive response to stresses. This article is part of a Special Issue entitled: Plant gene regulation in response to abiotic stress. © 2011 Elsevier B.V.en
dc.description.sponsorshipThis work was supported by USDA and NIH grants to J.-K. Zhu and by National Science Foundation grants IOS0919745 and MCB0950242 to J. Zhu.en
dc.publisherElsevieren
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175014en
dc.subjectAbioticen
dc.subjectBioticen
dc.subjectMiRNAen
dc.subjectPlanten
dc.subjectSiRNAen
dc.subjectStress responsesen
dc.titleRole of miRNAs and siRNAs in biotic and abiotic stress responses of plantsen
dc.typeArticleen
dc.contributor.departmentCenter for Desert Agricultureen
dc.identifier.journalBiochimica et Biophysica Acta - Gene Regulatory Mechanismsen
dc.identifier.pmcidPMC3175014en
dc.contributor.institutionDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN47907-2010, United Statesen
dc.contributor.institutionDepartment of Plant Science and Landscape Architecture, University of Maryland, College Park, MD 20742, United Statesen
kaust.authorKhraiwesh, Baselen
kaust.authorZhu, Jian-Kangen

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