A route to hydroxylfluorenes: TsOH-mediated condensation reactions of 1,3-diketones with propargylic alcohols

Handle URI:
http://hdl.handle.net/10754/562014
Title:
A route to hydroxylfluorenes: TsOH-mediated condensation reactions of 1,3-diketones with propargylic alcohols
Authors:
Yao, Liangfeng; Tan, Davin; Miao, Xiaohe; Huang, Kuo-Wei ( 0000-0003-1900-2658 )
Abstract:
An efficient method of preparing hydroxylfluorenes by TsOH-mediated tandem alkylation/rearrangements of propargylic alcohols with 1,3-diketones is described. These reactions are accomplished in moderate to good yields under mild conditions to offer a straightforward and convenient one step synthetic route to hydroxylfluorene derivatives through a plausible mechanism involving a sequence of dehydration, addition, rearrangement and aromatization. This journal is © The Royal Society of Chemistry 2012.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division; KAUST Catalysis Center (KCC); Chemical Science Program; Physical Sciences and Engineering (PSE) Division; HCL
Publisher:
Royal Society of Chemistry
Journal:
RSC Advances
Issue Date:
2012
DOI:
10.1039/c2ra20852k
Type:
Article
ISSN:
20462069
Sponsors:
We would like to acknowledge the financial support from the King Abdullah University of Science and Technology and the assistance given by the Core Laboratories.
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; Chemical Science Program; KAUST Catalysis Center (KCC); Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorYao, Liangfengen
dc.contributor.authorTan, Davinen
dc.contributor.authorMiao, Xiaoheen
dc.contributor.authorHuang, Kuo-Weien
dc.date.accessioned2015-08-03T09:42:51Zen
dc.date.available2015-08-03T09:42:51Zen
dc.date.issued2012en
dc.identifier.issn20462069en
dc.identifier.doi10.1039/c2ra20852ken
dc.identifier.urihttp://hdl.handle.net/10754/562014en
dc.description.abstractAn efficient method of preparing hydroxylfluorenes by TsOH-mediated tandem alkylation/rearrangements of propargylic alcohols with 1,3-diketones is described. These reactions are accomplished in moderate to good yields under mild conditions to offer a straightforward and convenient one step synthetic route to hydroxylfluorene derivatives through a plausible mechanism involving a sequence of dehydration, addition, rearrangement and aromatization. This journal is © The Royal Society of Chemistry 2012.en
dc.description.sponsorshipWe would like to acknowledge the financial support from the King Abdullah University of Science and Technology and the assistance given by the Core Laboratories.en
dc.publisherRoyal Society of Chemistryen
dc.titleA route to hydroxylfluorenes: TsOH-mediated condensation reactions of 1,3-diketones with propargylic alcoholsen
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.contributor.departmentChemical Science Programen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentHCLen
dc.identifier.journalRSC Advancesen
kaust.authorYao, Liangfengen
kaust.authorTan, Davinen
kaust.authorMiao, Xiaoheen
kaust.authorHuang, Kuo-Weien
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