Hexafluorobenzene: A powerful solvent for a noncovalent stereoselective organocatalytic Michael addition reaction

Handle URI:
http://hdl.handle.net/10754/561973
Title:
Hexafluorobenzene: A powerful solvent for a noncovalent stereoselective organocatalytic Michael addition reaction
Authors:
Lattanzi, Alessandra; De Fusco, Claudia; Russo, Alessio; Poater, Albert; Cavallo, Luigi ( 0000-0002-1398-338X )
Abstract:
A dramatic enhancement of the diastereo- and enantioselectivity in the nitro-Michael addition reaction organocatalysed by a commercially available α,α-l-diaryl prolinol was disclosed when performing the reaction in unconventional hexafluorobenzene as a medium. DFT calculations were performed to clarify the origin of stereoselectivity and the role of C 6F 6. © The Royal Society of Chemistry 2012.
KAUST Department:
Physical Sciences and Engineering (PSE) Division; Chemical Science Program; KAUST Catalysis Center (KCC)
Publisher:
Royal Society of Chemistry (RSC)
Journal:
Chem. Commun.
Issue Date:
2012
DOI:
10.1039/c2cc17488j
Type:
Article
ISSN:
13597345
Sponsors:
We thank MIUR for financial support and the Spanish MICINN for a Ramon y Cajal contract (RYC-2009-04170).
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; Chemical Science Program; KAUST Catalysis Center (KCC)

Full metadata record

DC FieldValue Language
dc.contributor.authorLattanzi, Alessandraen
dc.contributor.authorDe Fusco, Claudiaen
dc.contributor.authorRusso, Alessioen
dc.contributor.authorPoater, Alberten
dc.contributor.authorCavallo, Luigien
dc.date.accessioned2015-08-03T09:35:22Zen
dc.date.available2015-08-03T09:35:22Zen
dc.date.issued2012en
dc.identifier.issn13597345en
dc.identifier.doi10.1039/c2cc17488jen
dc.identifier.urihttp://hdl.handle.net/10754/561973en
dc.description.abstractA dramatic enhancement of the diastereo- and enantioselectivity in the nitro-Michael addition reaction organocatalysed by a commercially available α,α-l-diaryl prolinol was disclosed when performing the reaction in unconventional hexafluorobenzene as a medium. DFT calculations were performed to clarify the origin of stereoselectivity and the role of C 6F 6. © The Royal Society of Chemistry 2012.en
dc.description.sponsorshipWe thank MIUR for financial support and the Spanish MICINN for a Ramon y Cajal contract (RYC-2009-04170).en
dc.publisherRoyal Society of Chemistry (RSC)en
dc.titleHexafluorobenzene: A powerful solvent for a noncovalent stereoselective organocatalytic Michael addition reactionen
dc.typeArticleen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentChemical Science Programen
dc.contributor.departmentKAUST Catalysis Center (KCC)en
dc.identifier.journalChem. Commun.en
dc.contributor.institutionDipartimento di Chimica e Biologia, Via Ponte don Melillo, 84084, Fisciano, Italyen
dc.contributor.institutionCatalan Institute for Water Research (ICRA), H2O Building, Scientific and Technological Park of the University of Girona, Spainen
kaust.authorCavallo, Luigien
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