Role of biodegradation in the removal of pharmaceutically active compounds with different bulk organic matter characteristics through managed aquifer recharge: Batch and column studies

Handle URI:
http://hdl.handle.net/10754/561888
Title:
Role of biodegradation in the removal of pharmaceutically active compounds with different bulk organic matter characteristics through managed aquifer recharge: Batch and column studies
Authors:
Maeng, Sungkyu; Sharma, Saroj K.; Abel, Chol D T; Magic-Knezev, Aleksandra; Amy, Gary L.
Abstract:
Natural water treatment systems such as bank filtration have been recognized as providing effective barriers in the multi-barrier approach for attenuation of organic micropollutants for safe drinking water supply. In this study, the role of biodegradation in the removal of selected pharmaceutically active compounds (PhACs) during soil passage was investigated. Batch studies were conducted to investigate the removal of 13 selected PhACs from different water sources with respect to different sources of biodegradable organic matter. Neutral PhACs (phenacetine, paracetamol, and caffeine) and acidic PhACs (ibuprofen, fenoprofen, bezafibrate, and naproxen) were removed with efficiencies greater than 88% from different organic matter water matrices during batch studies (hydraulic retention time (HRT): 60 days). Column experiments were then performed to differentiate between biodegradation and sorption with regard to the removal of selected PhACs. In column studies, removal efficiencies of acidic PhACs (e.g., analgesics) decreased under conditions of limited biodegradable carbon. The removal efficiencies of acidic PhACs were found to be less than 21% under abiotic conditions. These observations were attributed to sorption under abiotic conditions established by a biocide (20 mM sodium azide), which suppresses microbial activity/biodegradation. However, under biotic conditions, the removal efficiencies of these acidic PhACs were found to be greater than 59%. This is mainly attributed to biodegradation. Moreover, the average removal efficiencies of hydrophilic (polar) neutral PhACs (paracetamol, pentoxifylline, and caffeine) with low octanol/water partition coefficients (log K ow less than 1) were low (11%) under abiotic conditions. However, under biotic conditions, removal efficiencies of the neutral PhACs were greater than 98%. In contrast, carbamazepine persisted and was not easily removed under either biotic or abiotic conditions. This study indicates that biodegradation represents an important mechanism for the removal of PhACs during soil passage. © 2011 Elsevier Ltd.
KAUST Department:
Biological and Environmental Sciences and Engineering (BESE) Division
Publisher:
Elsevier BV
Journal:
Water Research
Issue Date:
Oct-2011
DOI:
10.1016/j.watres.2011.05.043
PubMed ID:
21802106
Type:
Article
ISSN:
00431354
Sponsors:
We would like to acknowledge the help of Theo van der Kaaij and Ineke van der Veer-Agterberg (HetWaterlaboratorium) for the support on LC-OCD/OND and ATP measurements. We would like to express our gratitude to Dr. Sacher from DVGW-Technologiezentrum Wasser, Germany for PhACs measurements. This work was financially supported by EU SWITCH Project No. 018530-2 under the Sixth Framework Programme.
Appears in Collections:
Articles; Biological and Environmental Sciences and Engineering (BESE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorMaeng, Sungkyuen
dc.contributor.authorSharma, Saroj K.en
dc.contributor.authorAbel, Chol D Ten
dc.contributor.authorMagic-Knezev, Aleksandraen
dc.contributor.authorAmy, Gary L.en
dc.date.accessioned2015-08-03T09:33:23Zen
dc.date.available2015-08-03T09:33:23Zen
dc.date.issued2011-10en
dc.identifier.issn00431354en
dc.identifier.pmid21802106en
dc.identifier.doi10.1016/j.watres.2011.05.043en
dc.identifier.urihttp://hdl.handle.net/10754/561888en
dc.description.abstractNatural water treatment systems such as bank filtration have been recognized as providing effective barriers in the multi-barrier approach for attenuation of organic micropollutants for safe drinking water supply. In this study, the role of biodegradation in the removal of selected pharmaceutically active compounds (PhACs) during soil passage was investigated. Batch studies were conducted to investigate the removal of 13 selected PhACs from different water sources with respect to different sources of biodegradable organic matter. Neutral PhACs (phenacetine, paracetamol, and caffeine) and acidic PhACs (ibuprofen, fenoprofen, bezafibrate, and naproxen) were removed with efficiencies greater than 88% from different organic matter water matrices during batch studies (hydraulic retention time (HRT): 60 days). Column experiments were then performed to differentiate between biodegradation and sorption with regard to the removal of selected PhACs. In column studies, removal efficiencies of acidic PhACs (e.g., analgesics) decreased under conditions of limited biodegradable carbon. The removal efficiencies of acidic PhACs were found to be less than 21% under abiotic conditions. These observations were attributed to sorption under abiotic conditions established by a biocide (20 mM sodium azide), which suppresses microbial activity/biodegradation. However, under biotic conditions, the removal efficiencies of these acidic PhACs were found to be greater than 59%. This is mainly attributed to biodegradation. Moreover, the average removal efficiencies of hydrophilic (polar) neutral PhACs (paracetamol, pentoxifylline, and caffeine) with low octanol/water partition coefficients (log K ow less than 1) were low (11%) under abiotic conditions. However, under biotic conditions, removal efficiencies of the neutral PhACs were greater than 98%. In contrast, carbamazepine persisted and was not easily removed under either biotic or abiotic conditions. This study indicates that biodegradation represents an important mechanism for the removal of PhACs during soil passage. © 2011 Elsevier Ltd.en
dc.description.sponsorshipWe would like to acknowledge the help of Theo van der Kaaij and Ineke van der Veer-Agterberg (HetWaterlaboratorium) for the support on LC-OCD/OND and ATP measurements. We would like to express our gratitude to Dr. Sacher from DVGW-Technologiezentrum Wasser, Germany for PhACs measurements. This work was financially supported by EU SWITCH Project No. 018530-2 under the Sixth Framework Programme.en
dc.publisherElsevier BVen
dc.subjectBank filtrationen
dc.subjectBulk organic matteren
dc.subjectManaged aquifer rechargeen
dc.subjectOrganic micropollutantsen
dc.subjectPharmaceutically active compoundsen
dc.titleRole of biodegradation in the removal of pharmaceutically active compounds with different bulk organic matter characteristics through managed aquifer recharge: Batch and column studiesen
dc.typeArticleen
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Divisionen
dc.identifier.journalWater Researchen
dc.contributor.institutionWater Research Center, Korea Institute of Science and Technology, P.O. Box. 131, Cheongryang, Seoul 130-650, South Koreaen
dc.contributor.institutionUNESCO-IHE Institute for Water Education, P.O. Box 3015, 2601 DA Delft, Netherlandsen
dc.contributor.institutionHet Waterlaboratorium, J.W. Lucasweg 2, 2031 BE Haarlem, Netherlandsen
kaust.authorAmy, Gary L.en
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